Detecting Alzheimer's and mood disorders through voice analysis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The PLATA project aims to develop an algorithm that identifies vocal biomarkers associated with Alzheimer's disease and affective disorders. By analyzing speech patterns collected during routine care, the study will compare these patterns to established biomarkers like amyloid 1-42 and p-Tau found in cerebrospinal fluid. This innovative approach could potentially eliminate the need for invasive procedures such as lumbar punctures and PET scans for early detection of these conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 50 years
* Diagnosis relevant biomarker and neuropsychological data already available
* Cognitively healthy to very mild dementia (CDR score max. 0.5)
* Sufficient knowledge of the study language to understand study information, non opposition form,and questionnaires
* Expression of non opposition

Exclusion Criteria:

* Hearing problems
* Patient protected by law, under guardianship or curator ship, or not able to participate in a clinical study according to the article L.1121-16 of the French Public Health Code

Where it's running

• CHU de Nice
  Nice, France Recruiting

Study contacts

• Principal investigator: Eric ETTORE, MD — Centre Hospitalier Universitaire de Nice
• Study coordinator: Eric ETTORE, MD
• Email: ettore.e@chu-nice.fr
• Phone: 04.92.03.47.70

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.