Review of patients who had nail reconstruction after melanoma surgery

Review of the Literature and Retrospective, Single-centre Study of a Series of Patients Who Underwent Reconstruction After Complete Nail Resection.

Observational Centre Hospitalier Universitaire de Nice · NCT06861023

This study looks at how well different nail reconstruction methods work for patients who had melanoma surgery instead of having their nails amputated.

Quick facts

Study typeObservational
Enrollment10 (estimated)
SexAll
SponsorCentre Hospitalier Universitaire de Nice Academic / other
Locations1 site (Nice, Alpes Maritimes)
Trial IDNCT06861023 on ClinicalTrials.gov

What this trial studies

This study reviews patients who underwent reconstruction of the nail apparatus following wide local excision due to melanoma. It focuses on cases where the standard treatment of amputation was replaced with enlarged excision of the nail plate, allowing for various reconstruction techniques. The investigators present a series of patients treated with INTEGRA (dermal matrix) and skin grafts to assess outcomes and effectiveness. The observational nature of the study allows for a comprehensive analysis of patient experiences and results.

Who should consider this trial

Good fit: Ideal candidates are patients who have undergone enlarged resection of the nail apparatus due to acral melanoma of the fingers or toes.

Not a fit: Patients who have undergone amputation or those who oppose participation in the study will not benefit.

Why it matters

Potential benefit: If successful, this study could provide insights into effective reconstruction techniques that preserve finger or toe function and appearance after melanoma treatment.

How similar studies have performed: While this approach is less common, similar studies have shown promising outcomes in reconstructive techniques for melanoma, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who have undergone enlarged resection of the nail apparatus with immediate or delayed reconstruction in the setting of acral melanoma of the fingers or toes.

Exclusion Criteria:

* Patients who have amputation, opposition of the pateint to the study.

Where this trial is running

Nice, Alpes Maritimes

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Melanoma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.