Analyzing Inflammatory Biomarkers for Diagnosing CNS Autoimmune Diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to improve the diagnostic process for central nervous system diseases, particularly multiple sclerosis (MS), by analyzing inflammatory biomarkers in serum and cerebrospinal fluid (CSF). The study focuses on identifying specific cytokines and free light chains that could differentiate MS from other similar conditions. Patients referred for diagnostic work-ups of white matter lesions will have their blood and CSF analyzed to establish potential biomarkers for more accurate diagnoses. The goal is to enhance diagnostic accuracy and reduce the complexity of the diagnostic process for suspected MS cases.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients referred to our center for the diagnostic work-up of White Matter Lesions
* Patients that need a routine blood analysis
* Patients that need a routine CSF analysis
* Non opposition to research consent

Exclusion Criteria:

* Patients with a contraindication to perform spinal tap (increase bleeding risk medicine or disease)
* Patients with a contraindication to MRI (metal prosthesis…)

Where it's running

• Centre Hospitalier Universitaire de Nice
  Nice, France Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.