Polypharmacy and Healthy Aging in People Living with HIV Aged 75 and Older
Official title: Describe and Evaluate the Impact of Polypharmacy on Healthy Aging in People Living With HIV Over the Age of 75 Who Are Being Treated at Nice University Hospital.
Run by Centre Hospitalier Universitaire de Nice · NCT07388394 · Data updated 2026-11-12
We’re looking to see how polypharmacy affects older adults with HIV and whether a geriatric approach can help tailor care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 75 Years and up |
| Sex | All |
| Enrollment | 136 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Nice Academic / other |
| Locations | 1 site (Nice, CHU de Nice) |
| Status | Recruiting |
| Started | January 28, 2026 |
| Main results expected | August 31, 2027 |
| Study ends | August 31, 2027 |
| Registry record updated | October 29, 2026 |
| Trial ID | NCT07388394 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are HIV-positive individuals aged 75 or older who are affiliated with the French social security system and capable of consenting to an interview.
✕Probably not a fit
Patients unwilling or unable to participate or with severe cognitive impairment that prevents interview participation may not benefit from the study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on people living with HIV who are 75 years or older and receive care at Nice University Hospital. It will collect quantitative data and gather insights from interviews with advanced practice nurses to understand polypharmacy and potentially inappropriate prescriptions. The goal is to identify care pathways that address complex needs and support healthy aging as defined by WHO guidelines. No experimental drug interventions are involved; the study uses observational data to inform future care optimization. Results may inform adjustments to clinical pathways to improve safety and quality of life for this high-risk group.
Why it matters
Potential benefit: If successful, findings could lead to better-personalized medication management and care plans for very elderly PLHIV.
How similar studies have gone: Prior work in geriatric HIV care suggests care optimization can reduce polypharmacy-related risks, though this specific age group and setting is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * HIV-positive * Aged 75 or over * Affiliated with the social security system * Having expressed no objection to participating in the study Exclusion Criteria: * Refusal to participate * Known severe cognitive impairment preventing the interview from being conducted * Patient under guardianship or conservatorship
Where it's running
-
CHU de NICE
Nice, CHU de Nice, France Recruiting
Study contacts
- Study coordinator: Lysandre BLANCKEMAN
- Email: blanckerman.l@chu-nice.fr
- Phone: 04 92 03 54 67
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.