Upper-arm superficial vein thrombosis with catheter-related bloodstream infection in PICC or midline catheters
Official title: Superficial Vein Thrombosis of the Upper Limb in Bacteremia Associated With PICCline and Midline Catheters: Frequency and Clinical Consequences
Run by Centre Hospitalier Universitaire de Nice · NCT07388381 · Data updated 2026-11-12
This study tests how often superficial vein thrombosis occurs during catheter-related bloodstream infections in people with PICC or midline catheters.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Nice Academic / other |
| Locations | 1 site (Nice, CHU de Nice) |
| Status | Recruiting |
| Started | February 9, 2026 |
| Main results expected | October 30, 2027 |
| Study ends | October 30, 2027 |
| Registry record updated | June 22, 2026 |
| Trial ID | NCT07388381 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18) hospitalized with PICC or midline catheter and diagnosed with catheter-related bacteremia, in Nice, France.
✕Probably not a fit
Patients without upper-limb SVT or those without catheter-related bacteremia may not see a direct benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial examines the frequency and clinical impact of superficial vein thrombosis in the upper limb among adults with catheter-related bacteremia from PICC lines or midlines. It follows patients during their hospital stay to observe occurrence of SVT and its relation to infection duration and management. The study uses routine Doppler ultrasound and clinical data to describe outcomes in this setting. No intervention beyond standard follow-up for catheter-related bacteremia is described. Results could inform whether SVT should influence treatment decisions in catheter-associated infections.
Why it matters
Potential benefit: If SVT is found to significantly affect outcomes, findings could guide more tailored management of catheter-related infections in upper limbs.
How similar studies have gone: Other research has explored catheter-related infections and thrombosis, but this specific focus on upper-limb SVT with bacteremia is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Hospitalization in a department of Nice University Hospital * Expected length of hospitalization ≥ 72 hours * Diagnosis of catheter-related bacteremia on PICCline or Midline. * Affiliation with a social security system * No objection to the study Exclusion Criteria: * Pregnant or breastfeeding women * Legal protection measures (patients under guardianship, trusteeship, or judicial protection) * Inability to remove the catheter * Doppler ultrasound showing DVT in the upper limb at selection. * Inability to perform the initial routine Doppler ultrasound * Withdrawal of the patient's consent
Where it's running
-
CHU de NICE
Nice, CHU de Nice, France Recruiting
Study contacts
- Study coordinator: Elisa DEMONCHY
- Email: demonchy.e@chu-nice.fr
- Phone: 0492035847
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
NowCath Foley: a new catheter to lower bladder infections and blockages for long-term users
A new silicone indwelling catheter with extra drainage eyelets and a flexible skirt is being tested to see if it reduces catheter-associated urinary tract infections and blockages in adults who need long-term Foley catheters.
-
Adhesive versus elastic leg devices to secure urinary catheters in critically ill adults
This trial will test whether adhesive or elastic leg securement devices better prevent meatal injuries, reduce discomfort, and lower catheter-associated urinary tract infections in critically ill adults with urinary catheters.
-
Impact of catheter replacement on urinary tract infections
This study is testing if changing bladder catheters during treatment for urinary tract infections helps people avoid getting infections again compared to keeping their current catheters.
-
Comparing T-Control and Foley Catheters for Long-Term Bladder Catheter Patients
This pilot randomized study tests whether the T-Control catheter provides more comfort and a better experience than a standard Foley catheter for people needing a long-term bladder tube.
-
Improving prevention of catheter-related bloodstream infections in ICUs
This study is testing a new approach to help hospitals in intensive care units prevent infections related to catheters by making sure doctors and nurses follow the best care practices.
-
How bladder microbes and immune signals affect lower urinary tract health
This project will test whether differences in bladder microbes and immune signals are linked to urinary tract health in adults with and without various urinary conditions.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.