Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Upper-arm superficial vein thrombosis with catheter-related bloodstream infection in PICC or midline catheters

Official title: Superficial Vein Thrombosis of the Upper Limb in Bacteremia Associated With PICCline and Midline Catheters: Frequency and Clinical Consequences

Run by Centre Hospitalier Universitaire de Nice · NCT07388381 · Data updated 2026-11-12

This study tests how often superficial vein thrombosis occurs during catheter-related bloodstream infections in people with PICC or midline catheters.

More Catheter-Associated Urinary Tract Infection trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment150 (estimated)
SponsorCentre Hospitalier Universitaire de Nice
Academic / other
Locations1 site (Nice, CHU de Nice)
StatusRecruiting
StartedFebruary 9, 2026
Main results expectedOctober 30, 2027
Study endsOctober 30, 2027
Registry record updatedJune 22, 2026
Trial IDNCT07388381 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (≥18) hospitalized with PICC or midline catheter and diagnosed with catheter-related bacteremia, in Nice, France.

Probably not a fit

Patients without upper-limb SVT or those without catheter-related bacteremia may not see a direct benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial examines the frequency and clinical impact of superficial vein thrombosis in the upper limb among adults with catheter-related bacteremia from PICC lines or midlines. It follows patients during their hospital stay to observe occurrence of SVT and its relation to infection duration and management. The study uses routine Doppler ultrasound and clinical data to describe outcomes in this setting. No intervention beyond standard follow-up for catheter-related bacteremia is described. Results could inform whether SVT should influence treatment decisions in catheter-associated infections.

Why it matters

Potential benefit: If SVT is found to significantly affect outcomes, findings could guide more tailored management of catheter-related infections in upper limbs.

How similar studies have gone: Other research has explored catheter-related infections and thrombosis, but this specific focus on upper-limb SVT with bacteremia is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Hospitalization in a department of Nice University Hospital
* Expected length of hospitalization ≥ 72 hours
* Diagnosis of catheter-related bacteremia on PICCline or Midline.
* Affiliation with a social security system
* No objection to the study

Exclusion Criteria:

* Pregnant or breastfeeding women
* Legal protection measures (patients under guardianship, trusteeship, or judicial protection)
* Inability to remove the catheter
* Doppler ultrasound showing DVT in the upper limb at selection.
* Inability to perform the initial routine Doppler ultrasound
* Withdrawal of the patient's consent

Where it's running

  • CHU de NICE
    Nice, CHU de Nice, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.