Nerve ultrasound in people with Friedreich ataxia
Friedreich Ataxia Nerve Ultrasund and Clinical Correlations
This project uses routine peripheral nerve ultrasound to see if adults with genetically confirmed Friedreich ataxia have enlarged nerves.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 14 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire de Nice Academic / other |
| Locations | 1 site (Nice, Alpes Maritimes) |
| Trial ID | NCT07508631 on ClinicalTrials.gov |
What this trial studies
This is a single-center observational project at CHU de Nice using routine peripheral nerve ultrasound exams performed between December 2025 and April 2026. It includes adults aged 18–70 with a genetically confirmed diagnosis of Friedreich ataxia who are followed at the Neurogenetics Competence Centre. Sonographers record nerve size and appearance in the upper and lower limbs and compare findings to expected normal ranges. No experimental treatments are given; the aim is to better describe peripheral nerve involvement to inform clinical care and future research.
Who should consider this trial
Good fit: Adults aged 18–70 with genetically confirmed Friedreich ataxia who are followed at the Neurogenetics Competence Centre, CHU Nice, and who underwent peripheral nerve ultrasound between December 2025 and April 2026.
Not a fit: Patients under 18 or over 70, those without genetic confirmation, those not followed at CHU Nice, or those without available peripheral nerve ultrasound data would not be eligible and are unlikely to benefit from this project.
Why it matters
Potential benefit: If successful, the results could improve recognition and monitoring of peripheral nerve involvement in Friedreich ataxia and help guide clinical follow-up and future trials.
How similar studies have performed: Previous ultrasound work has reported nerve enlargement in some people with Friedreich ataxia, so this approach builds on emerging but still limited evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged between 18 and 70 years. * Genetically confirmed diagnosis of Friedreich's Ataxia. * Followed at the Neurogenetics Competence Centre, CHU Nice. * Have undergone peripheral nerve ultrasound between December 2025 and April 2026. Exclusion Criteria: * Patients for whom peripheral nerve ultrasound data is unavailable.
Where this trial is running
Nice, Alpes Maritimes
- CHU de Nice — Nice, Alpes Maritimes, France (Recruiting)
Study contacts
- Study coordinator: Andra Ezaru
- Email: ezaru.a@chu-nice.fr
- Phone: 07 80 65 10 81
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.