Home-based personalized training and video consultations for mitochondrial myopathy patients
Official title: Video Consultation and Mitochondrial Myopathies: Study of Efficacy and Tolerance of a Personalized Training Program at Home
Run by Centre Hospitalier Universitaire de Nice · NCT05346627 · Data updated 2026-11-12
This study tests whether a personalized training program and video consultations can help people with mitochondrial myopathy improve their health and quality of life.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 15 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Nice Academic / other |
| Locations | 1 site (Nice, Alpes Maritimes) |
| Status | Recruiting |
| Started | December 20, 2022 |
| Main results expected | June 2027 |
| Study ends | June 2027 |
| Registry record updated | June 24, 2026 |
| Trial ID | NCT05346627 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 with genetically-confirmed mitochondrial myopathy who can walk with or without assistance.
✕Probably not a fit
Patients with comorbidities or physical conditions that prevent participation in the training program may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the efficacy and tolerance of a personalized training program combined with video consultations for patients suffering from mitochondrial myopathies. It addresses the unique challenges faced by these patients, who often experience exercise intolerance and functional limitations. By tailoring a training regimen to their specific physical conditions, the study seeks to improve their overall health and quality of life. Participants will engage in a mixed training program while receiving ongoing support through video consultations.
Why it matters
Potential benefit: If successful, this approach could enhance the physical capabilities and quality of life for patients with mitochondrial myopathies.
How similar studies have gone: While there is growing interest in personalized exercise programs for similar conditions, this specific approach is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * patient over 18 years-old, * with genetically-confirmed mitochondria myopathy, * with mitochondrial DNA mutation, * clinically dominant myopathic-like disorders according investigator, * able to walk with or without assistance, * likely to be followed for at least one year without interruption by video consultation (implying internet connexion with computer and camera or smartophone), * having given the written and informed consent and being social security member. * For patients in childbearing age, she must have used at least one month if reliable contraception. Exclusion criteria: * patient wih pathology or comorbidity incompatible with the conduct of the study according the investigator during inclusion visit, * patient with physical condition incompatible with training program according investigator during inclusion visit, * patient having a physical tiredness and/or myalgia during last week with an intensity of 6 on visual and analog scale, * pregnant or nursing patient, * patient expecting pregnancy during the course of the study, * patient protected by law or under guardianship or curatorship, or not able to participate in a clinical trial under L.1121-16 article of French Public Health Regulations.
Where it's running
-
CHU de Nice
Nice, Alpes Maritimes, France Recruiting
Study contacts
- Study coordinator: Sabrina SACCONI
- Email: sacconi.s@chu-nice.fr
- Phone: 04 92 03 57 57
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.