Evaluating eye movement diagnostics for neurological conditions
Diagnostic Value of Digital Video Oculography in Patients With White Matter Lesions
This study is testing if a new eye movement test can help find hidden neurological problems in people with multiple sclerosis and related conditions.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire de Nice Academic / other |
| Locations | 1 site (Nice) |
| Trial ID | NCT05776511 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the diagnostic value of electronic video oculography (eVOG) in patients with multiple sclerosis, radiologically isolated syndrome, and white matter lesions. The study aims to assess eye movement patterns to identify potential neurological disorders that may not be evident through conventional clinical examinations. Patients over 18 years old, referred for diagnostic workups, will be included, while controls will be recruited from hospital staff and accompanying persons. The trial focuses on understanding how eye movement can reveal underlying neurological issues.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years old referred for diagnostic evaluation of white matter hypersignals without oculomotor disorders.
Not a fit: Patients with existing neurological, ophthalmological, or general pathologies that could affect eye movement assessments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance diagnostic accuracy for neurological conditions, leading to earlier and more effective treatment.
How similar studies have performed: While the specific use of eVOG in this context may be novel, similar studies have shown promise in using eye movement analysis for diagnosing neurological conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Patients Inclusion Criteria: * Patients referred to our tertiary center for a diagnostic workup of white matter hypersignals * Absence of oculomotor disorders on conventional clinical examination * Age \> 18 years controls Inclusion criteria: * The controls can be recruited from the accompanying persons of the patients selected for the study, from the staff of the CHU of Nice or from the entourage of the investigating team; * Absence of known oculomotor disorders by the control * Age \> 18 years Exclusion Criteria: * Presence of a neurological, ophthalmological or general pathology that may interfere with the performance of digital video oculography
Where this trial is running
Nice
- Nice University Hospital — Nice, France (Recruiting)
Study contacts
- Study coordinator: Mikael COHEN
- Email: cohen.m@chu-nice.fr
- Phone: 33492038252
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.