Evaluating eye movement diagnostics for neurological conditions
Official title: Diagnostic Value of Digital Video Oculography in Patients With White Matter Lesions
Run by Centre Hospitalier Universitaire de Nice · NCT05776511 · Data updated 2026-11-12
This study is testing if a new eye movement test can help find hidden neurological problems in people with multiple sclerosis and related conditions.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Nice Academic / other |
| Locations | 1 site (Nice) |
| Status | Recruiting |
| Started | April 7, 2023 |
| Main results expected | April 1, 2025 |
| Study ends | April 1, 2027 |
| Registry record updated | June 16, 2026 |
| Trial ID | NCT05776511 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 years old referred for diagnostic evaluation of white matter hypersignals without oculomotor disorders.
✕Probably not a fit
Patients with existing neurological, ophthalmological, or general pathologies that could affect eye movement assessments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the diagnostic value of electronic video oculography (eVOG) in patients with multiple sclerosis, radiologically isolated syndrome, and white matter lesions. The study aims to assess eye movement patterns to identify potential neurological disorders that may not be evident through conventional clinical examinations. Patients over 18 years old, referred for diagnostic workups, will be included, while controls will be recruited from hospital staff and accompanying persons. The trial focuses on understanding how eye movement can reveal underlying neurological issues.
Why it matters
Potential benefit: If successful, this study could enhance diagnostic accuracy for neurological conditions, leading to earlier and more effective treatment.
How similar studies have gone: While the specific use of eVOG in this context may be novel, similar studies have shown promise in using eye movement analysis for diagnosing neurological conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Patients Inclusion Criteria: * Patients referred to our tertiary center for a diagnostic workup of white matter hypersignals * Absence of oculomotor disorders on conventional clinical examination * Age \> 18 years controls Inclusion criteria: * The controls can be recruited from the accompanying persons of the patients selected for the study, from the staff of the CHU of Nice or from the entourage of the investigating team; * Absence of known oculomotor disorders by the control * Age \> 18 years Exclusion Criteria: * Presence of a neurological, ophthalmological or general pathology that may interfere with the performance of digital video oculography
Where it's running
-
Nice University Hospital
Nice, France Recruiting
Study contacts
- Study coordinator: Mikael COHEN
- Email: cohen.m@chu-nice.fr
- Phone: 33492038252
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.