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Clinical trials and research at Nantes University Hospital

• 144Clinical trials
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All recruiting trials (144)

• Four-session focal shock wave therapy for vulvodynia in women

  This study looks at whether four weekly sessions of low-intensity focal shock wave therapy help women with vulvodynia in real-life clinical practice.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT07553715

• Reproducibility of Digital Bite Mark Overlays in Adults

  This study tests how consistently different people can create digital bite mark overlays from 3D dental scans in adults who need routine dental care.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT07552051

• Dental care for people living with HIV in Pays de la Loire

  This study looks at whether people living with HIV in Pays de la Loire need any special dental management based on their health data.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT07552038

• 68Ga-FAPI-46 PET imaging to stage ATTR-CM and spot progression

  This study tests whether a gallium-68 labeled FAPI PET scan can help stage transthyretin cardiac amyloidosis and identify patients whose disease is progressing.

  Recruiting Phase 2 Nantes University Hospital · Nantes · NCT07549841

• IL-1β blocker after pancreatic transplant to help prevent graft thrombosis

  This trial tests whether adding Anakinra right after pancreatic transplant is safe for patients to see if it helps protect the new pancreas.

  Recruiting Phase 1/2 Nantes University Hospital · Nantes and 1 other locations · NCT07503834

• Synovial tissue biomarker study to guide PVNS management

  Researchers will collect and analyze synovial tissue from adults with PVNS to see if tissue markers can help tailor treatment.

  Recruiting Nantes University Hospital · Lyon and 2 other locations · NCT07503821

• Home-based tDCS for depression: comparing treatment done at home vs in hospital

  This study tests whether delivering transcranial direct current stimulation at home is as effective as in-hospital treatment for adults with moderate to severe depression.

  Recruiting Nantes University Hospital · Anglet and 5 other locations · NCT07490379

• Synovial Tissue as a Biomarker to Guide Early Osteoarthritis Care

  This study tests whether examining synovial tissue early in osteoarthritis can reveal biomarker pathotypes that relate to how the disease presents and progresses.

  Recruiting at 2 sites Nantes University Hospital · Nantes and 1 other locations · NCT07473414

• Gait and Achilles Tendon Properties in Spastic Paresis

  This study tests how the Achilles tendon and calf muscle function during walking in people with spastic weakness after stroke or spinal cord injury, compared with healthy individuals.

  Recruiting Nantes University Hospital · Nantes · NCT07467382

• Switching to aflibercept 8 mg in exudative AMD

  This real-world study looks at whether switching to a higher-dose aflibercept can extend treatment intervals for adults with exudative AMD who previously needed frequent injections.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT07423429

• Pre-surgery strength program for adults with ACL tears

  This project will test whether a 9-week progressive resistance training program before ACL reconstruction can increase knee muscle strength and size in adults waiting for surgery.

  Recruiting Nantes University Hospital · Nantes · NCT07411625

• Ultrasound to measure muscle quality and fat in older adults during rehab

  We’re testing an ultrasound-based method to see if higher intramuscular fat at the start predicts poorer recovery in physical function for older adults 75+ undergoing rehab.

  Recruiting Nantes University Hospital · Nantes · NCT07411547

• Driving pressure adjustment for high-frequency jet ventilation during tumor ablation

  This study will test whether using a height-based driving pressure for high-frequency jet ventilation improves breathing stability during thermal ablation in adults with non-brain solid tumors.

  Recruiting at 5 sites Nantes University Hospital · Lyon and 6 other locations · NCT07408375

• Oral-health training for nursing home caregivers to improve residents' quality of life

  This trial will test whether training nursing home caregivers in oral care can improve oral-health-related quality of life for residents aged 65 and older who are mentally independent.

  Recruiting Nantes University Hospital · Nantes · NCT07399925

• Psilocybin-assisted psychotherapy for gambling disorder

  This pilot study tests whether psilocybin-assisted psychotherapy can help adults with gambling disorder see if they have fewer symptoms after treatment.

  Recruiting Phase 2 Nantes University Hospital · Nantes · NCT07391332

• Ultrafast ultrasound biomarkers to track Duchenne and Becker muscular dystrophy

  This study tests whether multiparametric ultrafast ultrasound can non-invasively monitor disease progression in people with Duchenne or Becker muscular dystrophy.

  Recruiting Nantes University Hospital · Nantes · NCT07378553

• Time-restricted eating for fatty liver disease in obesity

  This study tests whether an 8-hour daily eating window can reduce liver fat in adults with obesity and MASLD, using coaching and a phone app alongside standard care.

  Recruiting Nantes University Hospital · Angers and 8 other locations · NCT07378072

• Perforator flap vs full-th thickness skin graft after melanoma surgery

  This observational pilot compares perforator flap reconstruction to skin grafting after margin re-excision for stage II cutaneous melanoma to see which approach supports better healing and appearance.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT07354152

• Rifampin-free therapy vs rifampin-containing therapy for staphylococcal prosthetic valve endocarditis

  This study tests whether a rifampin-free antibiotic regimen can be as effective as a rifampin-containing regimen for adults with staphylococcal prosthetic valve endocarditis.

  Recruiting at 29 sites Phase 3 Nantes University Hospital · Aix-les-Bains and 30 other locations · NCT07345325

• Simulation care pathway to prepare young children for MRI

  This project will test an immersive simulation to help children aged 3 to 6 prepare for their first MRI.

  Recruiting Nantes University Hospital · Nantes · NCT07344753

• Adaptation and tolerance of Essilor Stellest lenses in children with progressive myopia

  This observational pilot tests how well children with progressive myopia adapt to and tolerate Essilor Stellest lenses in real life.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT07340931

• Early continuous hypertonic saline infusion to improve 6-month neurological outcome after traumatic brain injury

  This trial will test whether giving a continuous intravenous infusion of hypertonic saline early after traumatic brain injury helps people survive and regain independence in daily life at 6 months.

  Recruiting at 10 sites Phase 3 Nantes University Hospital · Angers and 22 other locations · NCT07319208

• Preoperative romiplostim to raise platelets before cardiac surgery

  This test tries whether a short course of romiplostim can raise platelet counts so adults with low platelets can safely have cardiac surgery with cardiopulmonary bypass.

  Recruiting Phase 2 Nantes University Hospital · Angers and 7 other locations · NCT07278661

• Lidocaine to Help Spare Opioids During Vaso-occlusive Crises in Sickle Cell Disease

  This study tests whether adding lidocaine to standard pain care during a vaso-occlusive crisis can reduce the total opioid use in adults with sickle cell disease.

  Recruiting at 12 sites Phase 3 Nantes University Hospital · Bordeaux and 11 other locations · NCT07274254

• Clindamycin instead of vancomycin for aortic heart surgery with cardiopulmonary bypass

  This trial will try clindamycin as the antibiotic given around the time of aortic heart surgery with extracorporeal circulation for adults, including those who may have problems with vancomycin.

  Recruiting Phase 2 Nantes University Hospital · Nantes, France · NCT07267013

• Outpatient induction of labour with a double‑balloon transcervical catheter for low‑risk pregnant women

  This trial will test whether starting cervical ripening at home with a double‑balloon catheter is as safe, acceptable, and time‑efficient as staying in hospital for low‑risk pregnant women due for induction of labour.

  Recruiting at 2 sites Nantes University Hospital · Nantes, Loire Atlantique and 1 other locations · NCT07265518

• Association Between Severe Periodontitis and Arterial Stiffness: The PAROCAR Study

  This study tests whether adults with generalized stage 3-4 periodontitis have greater arterial stiffness than healthy adults, to see if severe gum disease links to higher cardiovascular risk.

  Recruiting Nantes University Hospital · Nantes · NCT07263113

• Stratifying risk of dangerous heart rhythm problems and heart failure in inherited heart disease

  This project will try to use routine clinical data, extra blood or saliva samples, and AI to see if it can predict which people with hereditary heart disease and their relatives are more likely to develop life‑threatening arrhythmias or heart failure.

  Recruiting Nantes University Hospital · Bordeaux and 14 other locations · NCT07257289

• Left bundle branch area pacing versus conventional right‑ventricular pacing after TAVI for atrioventricular block

  This will test whether left bundle branch area pacing works better than standard right‑ventricular pacing for people who need a pacemaker after TAVI.

  Recruiting at 6 sites Nantes University Hospital · Brest, Finistère and 6 other locations · NCT07236489

• Wastewater monitoring for antibiotic-resistant bacteria in nursing homes

  This project will test whether the amount of resistant bacteria in nursing home wastewater can indicate how many residents carry those bacteria.

  Recruiting at 2 sites Nantes University Hospital · Angers and 1 other locations · NCT07234331

• Telemonitoring and coordination to support digestive surgery patients

  This study tests whether a telemonitoring and tele-coordination platform can help adults after colorectal or bariatric surgery be monitored at home or in hospital to reduce readmissions and complications.

  Recruiting Nantes University Hospital · Nantes, Nantes and 1 other locations · NCT07186738

• Multiplexed PET imaging for detecting and staging liver and gastro‑entero‑pancreatic tumors

  This study will try using multiple PET tracers to see if combined scans better detect and stage hepatocellular carcinoma and gastro‑entero‑pancreatic tumors in adults.

  Recruiting Nantes University Hospital · Brest and 2 other locations · NCT07178587

• See if 12-lead ECG can predict S-ICD eligibility for adults

  This study tests whether a standard 12-lead ECG can predict who is suitable for a subcutaneous defibrillator (S-ICD) before implantation.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT07157449

• Measuring how the right ventricle and pulmonary artery work together in valve disease

  This project will test whether non-invasive heart imaging can match invasive catheter measurements of right ventricular–pulmonary artery coupling in adults with significant valvular heart disease.

  Recruiting Nantes University Hospital · Nantes, Loire Atlantique · NCT07112391

• Clinical, genetic, and immune causes of life-threatening bacterial infections in children

  This project will use clinical reviews, immune tests, and whole-exome sequencing to see if genetic or immune problems explain why some children who were in pediatric intensive care developed very severe bacterial infections.

  Recruiting Nantes University Hospital · Nantes, Loire Atlantique and 6 other locations · NCT07111793

• Why some people with chronic lymphocytic leukemia respond to BTK degrader drugs

  This project collects blood, bone marrow, or leftover lymph node samples from adults with CLL who are candidates for or have received BTK degrader drugs to see why some people respond and others become resistant.

  Recruiting at 2 sites Nantes University Hospital · Angers and 13 other locations · NCT07099443

• Targeted Temperature Management at 33°C for in-hospital cardiac arrest

  This trial tests whether cooling patients who remain unconscious after a resuscitated in-hospital cardiac arrest to 33°C improves survival with good brain function compared to keeping a normal, controlled temperature.

  Recruiting at 31 sites Nantes University Hospital · Ghent, Belgium and 30 other locations · NCT07086703

• Early check of quadriceps strength in ICU patients on invasive ventilation

  This study tests whether early measurement of quadriceps strength using dynamometry and 3D ultrasound can help track recovery in adults in the ICU who are on invasive mechanical ventilation.

  Recruiting Nantes University Hospital · Nantes, Loire Atlantique · NCT07069959

• Dietary oleic acid to change cholesterol handling in fat tissue of people with obesity

  This project will test whether adding oleic-acid–rich oil to the diet of women with obesity before bariatric surgery increases cholesterol esterification in their fat tissue.

  Recruiting Nantes University Hospital · Nantes, France · NCT07027033

• Partial versus complete thymus removal during infant heart surgery

  This will test whether removing only part of the thymus instead of the whole gland during heart surgery helps preserve immune function in infants under 6 months.

  Recruiting Nantes University Hospital · Nantes and 1 other locations · NCT07019857

• Frailty and sarcopenia in fibrosing ILDs: what it means for prognosis and care

  This study tests how frailty and muscle loss together affect outcomes in people aged 65 and older with fibrosing interstitial lung diseases who are treated in outpatient settings.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT07004595

• Ethical considerations of using gene therapy for exudative AMD

  This study tests how patients with exudative AMD feel about gene therapy and how much they want to participate in decisions about this surgically delivered, irreversible treatment.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT07004361

• Multiparametric dynamic whole-body [68Ga]Ga-PSMA PET/CT for hepatocellular carcinoma

  This will test whether multiparametric dynamic whole-body [68Ga]Ga-PSMA PET/CT can better detect and characterize hepatocellular carcinoma in adults who are newly diagnosed or who have suspected recurrent, residual, or refractory disease.

  Recruiting Nantes University Hospital · Clichy and 1 other locations · NCT06999837

• Botulinum toxin injected into the uterine muscle to reduce severe menstrual pain

  This trial will test whether a single botulinum toxin injection into the uterine wall via hysteroscopy can reduce severe menstrual cramps in women who did not get relief from first-line hormonal and pain treatments, compared with a placebo injection.

  Recruiting at 7 sites Phase 3 Nantes University Hospital · Aix-en-Provence and 7 other locations · NCT06995287

• Early dexamethasone to lower complications and death after severe burns

  This test gives early dexamethasone or placebo to adults with severe burns who are on mechanical ventilation to see if it reduces major complications and death.

  Recruiting Phase 3 Nantes University Hospital · Chambray-lès-Tours and 9 other locations · NCT06968559

• Determinants of coronary atherosclerosis in familial hypercholesterolemia

  We will use coronary CT scans to see how common hidden coronary artery plaque is in adults with familial hypercholesterolemia who do not yet have clinical heart disease.

  Recruiting at 7 sites Nantes University Hospital · Dijon and 8 other locations · NCT06960902

• Adding cognitive training to methylphenidate for adults with ADHD and addiction

  This study tests whether adding a cognitive training program to methylphenidate helps adults with ADHD and addiction improve day-to-day functioning.

  Recruiting Nantes University Hospital · Brest, Brittany Region and 5 other locations · NCT06906328

• At-home continuous monitoring after colorectal surgery to reduce readmissions

  This trial tests whether 30 days of at-home continuous remote monitoring after colorectal surgery helps people at higher risk of readmission compared with usual discharge care.

  Recruiting at 13 sites Nantes University Hospital · Angers and 13 other locations · NCT06850688

• Long-term follow-up of infants with congenital nevus

  Track children under 2 with medium-to-giant congenital nevi to see if they develop neurological problems, melanoma risk, or psychosocial impacts as they grow.

  Recruiting at 16 sites Nantes University Hospital · Nice, Alpes-Maritimes and 15 other locations · NCT06828822

• Endometriosis Steroid Profile and Biomarker Discovery

  This study tests a new method to map how steroids are processed in people with and without endometriosis by collecting blood, urine, and vaginal samples to find biomarkers related to the disease.

  Recruiting Nantes University Hospital · Nantes · NCT06820450

• Understanding how general practitioners manage burnout in everyday practice

  This study tests how French general practitioners think and act when handling burnout to see why practices vary.

  Recruiting Nantes University Hospital · Nantes · NCT06811181

• Using Point of Care Ultrasound to Diagnose Small Bowel Obstruction in Emergency Departments

  This study tests whether using ultrasound in the emergency department can help doctors quickly and safely diagnose small bowel obstruction instead of relying on CT scans.

  Recruiting at 17 sites Nantes University Hospital · Clermont-Ferrand, France and 17 other locations · NCT06803628

• How oxygen levels relate to when circulation stops during controlled (Maastricht III) organ donation

  This research will test how oxygen levels change around the time the heart stops in adults who undergo controlled Maastricht III organ donation.

  Recruiting at 11 sites Nantes University Hospital · Angers and 11 other locations · NCT06780722

• Autologous expanded regulatory CD8+ T cell therapy for living-donor kidney transplant recipients

  This trial will test whether infusing a patient's own expanded regulatory CD8+ T cells (Eight Treg) around a living-donor kidney transplant can help the graft survive better and lower the need for standard immunosuppressive drugs.

  Recruiting Phase 1 Nantes University Hospital · Nantes · NCT06777719

• Impact of a Snoezelen Element on Anxiety During Dental Care

  This real-life study tests whether using the Tovertafel Pixie sensory projector in a Nantes dental department reduces anxiety for adults receiving dental care.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT06776653

• Vitamin D3 before dental implants to help bone healing

  This pilot looks at whether taking vitamin D3 for six months helps implant bone integration in adults with vitamin D deficiency who are getting dental implants.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT06776640

• Evaluating protein levels in children undergoing cardiac surgery

  This study is testing how certain protein levels in children having heart surgery might relate to their recovery and complications after the operation.

  Recruiting Nantes University Hospital · Nantes · NCT06754709

• Evaluating blood protein levels in children with sepsis

  This study is testing the levels of a specific protein change in the blood of children with sepsis to see if it can help improve their treatment and recovery.

  Recruiting Nantes University Hospital · Nantes · NCT06754696

• Survey of adults in decentralized clinical trials

  This study is trying to see if adults in regular clinical trials would be open to joining decentralized trials that let them participate from home using digital tools.

  Recruiting Nantes University Hospital · Nantes · NCT06751641

• Evaluating chyme reinfusion methods after small bowel surgery

  This study is testing if a method called chyme reinfusion can help patients with serious digestive issues after bowel surgery by improving their nutrition and reducing fluid loss.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT06751628

• Immediate versus confirmed-start antibiotics for suspected non-severe ventilator-associated pneumonia

  This study will try starting antibiotics right away versus waiting for lab confirmation in adults on a ventilator who have a first suspected non-severe VAP.

  Recruiting at 42 sites Nantes University Hospital · Angers, France and 41 other locations · NCT06743529

• Home monitoring for babies after heart surgery

  This project tests a home monitoring system with telemedicine to help babies up to 3 years old who had congenital heart surgery to catch problems early and keep them safe at home.

  Recruiting Nantes University Hospital · Nantes · NCT06741189

• PET/CT with zirconium‑labelled girentuximab to image CAIX in liver and gastro‑entero‑pancreatic neuroendocrine tumors

  This will test whether a PET/CT scan using zirconium‑labelled girentuximab can find CAIX‑expressing hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and gastro‑entero‑pancreatic neuroendocrine tumors in adults.

  Recruiting Nantes University Hospital · Nantes and 1 other locations · NCT06735560

• COSCINUS cohort and biocollection for spinal cord injury

  This project collects clinical information and blood, urine, and stool samples to see patterns and risk factors in people with spinal cord injury.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT06734000

• Choosing the best drug for quick anesthesia induction in surgery

  This study tests whether propofol, ketamine, or a mix of both can help people get safely and quickly ready for surgery while keeping their blood pressure stable.

  Recruiting at 11 sites Phase 3 Nantes University Hospital · Angers and 19 other locations · NCT06733129

• Optimized bedside brain monitoring for newborns and infants in intensive care

  This project will try adding extra EEG electrodes and automated analysis to bedside monitoring to better find seizures and other brain problems in babies and children under 2 in intensive care.

  Recruiting Nantes University Hospital · Nantes · NCT06726408

• Support program for patients with unruptured intracranial aneurysms

  This study is testing a new support program to see if it helps people with unruptured intracranial aneurysms feel better and manage their condition more effectively.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT06708078

• Support and characterization of neurodevelopmental disorders in newborns with congenital heart defects

  This project will try to see how often and why babies with prenatally diagnosed critical congenital heart defects develop early neurodevelopmental problems by following them from before birth through infancy.

  Recruiting at 6 sites Nantes University Hospital · Nantes, Loire Atlantique and 7 other locations · NCT06690151

• Collection of data and samples linked to the French Register of Intracranial Aneurysms

  This study is trying to gather information and samples to help understand different types of brain aneurysms and see if genetics can help predict their risk of bursting.

  Recruiting at 10 sites Nantes University Hospital · Nantes, Loire-Atlantique and 25 other locations · NCT06689410

• Biocollection of AML, ALL, or high-risk MDS patients at Nantes

  This project collects extra blood or bone marrow samples from adults with AML, ALL, or high-risk MDS to help INSERM researchers study the disease.

  Recruiting Nantes University Hospital · Nantes · NCT06681363

• Bariatric surgery and biological aging in Nantes patients

  This project will see if bariatric surgery changes biological age and related factors like fat‑cell function, gut bacteria, and daily biological rhythms in adults undergoing surgery at Nantes University Hospital.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT06625762

• Advanced Practice Nurses helping prevent falls in older adults

  This study is testing if a fall prevention program run by Advanced Practice Nurses can help older adults aged 80 and up avoid falls better than regular care.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT06617806

• Understanding how pneumonia affects heart and lung health over time

  This study looks at how hospital-acquired pneumonia affects heart and lung health over time to help understand the long-term risks for patients.

  Recruiting Nantes University Hospital · Angers and 4 other locations · NCT06602934

• Evaluating a mobile hybrid room for vascular surgery

  This study is testing whether using a new mobile imaging system during vascular surgery can improve patient outcomes and reduce costs compared to standard X-ray methods for people with specific blood vessel conditions.

  Recruiting Nantes University Hospital · Besançon, Besançon and 6 other locations · NCT06590532

• Rehabilitation program for ICU patients on mechanical ventilation

  This study is testing a special rehabilitation program that includes nutrition and exercise for ICU patients on ventilators to see if it helps them recover better after their hospital stay.

  Recruiting at 52 sites Nantes University Hospital · Albi and 51 other locations · NCT06581939

• Using Posaconazole to Prevent Fungal Infections in High-Risk Stem Cell Transplant Patients

  This study is testing if Posaconazole can help prevent serious fungal infections in patients who are at high risk after receiving a stem cell transplant.

  Recruiting Phase 2 Nantes University Hospital · Nantes, France · NCT06541067

• Tight management for shoulder pain from rotator cuff tendinopathy

  This study is testing if more regular check-ins and support for people with early shoulder pain from rotator cuff tendinopathy can help them feel better faster compared to just one visit after three months.

  Recruiting at 8 sites Nantes University Hospital · Angers and 7 other locations · NCT06517680

• Exploring the Skin's Role in Frontotemporal Lobar Degeneration

  This study is testing how changes in the skin might relate to frontotemporal lobar degeneration in people with the condition and comparing it to healthy volunteers.

  Recruiting Nantes University Hospital · Nantes · NCT06490822

• Ongoing collection of blood and tumor samples from people with lung cancer

  Collect and store blood and tumor samples over time from adults with newly diagnosed or metastatic lung cancer to build a real-world biobank for research.

  Recruiting Nantes University Hospital · Angers and 3 other locations · NCT06481813

• Pharmaco-mechanical thrombolysis plus anticoagulation vs anticoagulation alone for acute iliofemoral DVT

  This trial tests whether adding pharmaco-mechanical thrombolysis to standard anticoagulation helps people with acute iliofemoral DVT.

  Recruiting Phase 4 Nantes University Hospital · Nantes · NCT06472518

• Predicting blockages in external ventricular drains for ICU patients

  This study is trying to find out which ICU patients with external ventricular drains are at higher risk for blockages after bleeding in the brain, to help improve their care.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT06466811

• Validation of a French questionnaire for assessing quality of life in primary hyperparathyroidism

  This study is testing a French questionnaire to see how primary hyperparathyroidism affects the quality of life for patients, including those who have had surgery and those who haven't.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT06450431

• Using echocardiography to improve heart care in nursing homes

  This study tests if using echocardiograms in nursing homes can help improve heart care and reduce hospital visits for residents with heart disease.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT06445231

• Understanding neurodevelopmental disorders in children with congenital heart defects

  This study is trying to see how heart surgery in young children with serious heart defects affects their brain development and behavior as they grow up.

  Recruiting at 5 sites Nantes University Hospital · Brest, Brittany Region and 4 other locations · NCT06442592

• Evaluating plasma cytokines in patients with certain blood cancers treated with non-intensive chemotherapy

  This study is trying to see if measuring certain proteins in the blood can help predict how well patients with specific blood cancers do when they receive two different types of chemotherapy.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT06439199

• Assessing brain injury in cardiac arrest patients

  This study is trying to find a better way to check for brain injuries in patients who have had a cardiac arrest to help decide who needs special treatments to improve their recovery.

  Recruiting at 4 sites Nantes University Hospital · La Roche-sur-Yon and 3 other locations · NCT06387225

• Evaluating early pulmonary vein isolation for elderly patients with atrial fibrillation

  This study tests if an early procedure called pulmonary vein isolation can help older patients with atrial fibrillation feel better compared to standard treatment with medications.

  Recruiting Nantes University Hospital · Nantes, Loire Atlantique · NCT06322017

• Comparing bougie-assisted intubation to standard intubation in emergency settings

  This study tests if using a bougie with an endotracheal tube during emergency intubation helps patients have a safer and more successful experience compared to using the tube alone.

  Recruiting at 8 sites Nantes University Hospital · Nantes, Loire Atlantique and 9 other locations · NCT06307392

• Self-guided pelvic-floor device plus rehab vs standard pelvic rehab for stress incontinence

  A device-assisted program with 3 monthly short device sessions plus 2 rehab visits is being tested to see if it works as well as the standard pelvic-perineal rehabilitation for women with stress urinary incontinence.

  Recruiting Nantes University Hospital · Nantes · NCT06285292

• Examining blood vessel changes in advanced glaucoma patients

  This study is testing how changes in blood vessels around the optic nerve affect vision loss in people with advanced glaucoma over three years.

  Recruiting Nantes University Hospital · Nantes, Nantes and 1 other locations · NCT06274593

• Exploring kidney transplant tolerance using blood samples

  This study looks at blood samples from kidney transplant patients to see if certain immune cells can help prevent the body from rejecting the new kidney.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT06271343

• Switching patients with AMD from ranibizumab or aflibercept to faricimab

  This study is testing if switching people with age-related macular degeneration from their current eye injections to a new treatment called faricimab can improve their vision and reduce the number of injections they need.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT06271330

• Evaluating complications after Nissen sleeve gastrectomy for obesity

  This study is testing if a new type of weight loss surgery called Nissen sleeve gastrectomy causes fewer complications than the regular sleeve gastrectomy for people with obesity.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT06271317

• Using dexamethasone to treat severe hospital-acquired pneumonia in critically ill patients

  This study is testing if adding dexamethasone to standard treatment helps critically ill patients with severe hospital-acquired pneumonia feel better compared to those who only get standard treatment.

  Recruiting at 19 sites Phase 3 Nantes University Hospital · Amiens and 33 other locations · NCT06269900

• Comparing imaging techniques for oral health in patients with infective endocarditis

  This study is testing if a special type of dental scan called Cone Beam Computed Tomography can find oral infections better than a regular dental X-ray in patients with infective endocarditis to help improve their oral health.

  Recruiting at 10 sites Nantes University Hospital · Bordeaux and 9 other locations · NCT06269679

• Cohort study of patients with Inflammatory Bowel Disease in Nantes

  This study is trying to collect samples from patients with Inflammatory Bowel Disease to see if they can find new signs that help guide better treatments over the next year.

  Recruiting Nantes University Hospital · Nantes and 2 other locations · NCT06256393

• Testing a new approach to prevent graft-versus-host disease after stem cell transplantation

  This study is testing a new treatment to see if a combination of two drugs can help prevent graft-versus-host disease in patients receiving stem cell transplants, allowing them to stop taking immunosuppressive drugs sooner.

  Recruiting at 3 sites Phase 2 Nantes University Hospital · Angers and 2 other locations · NCT06252870

• Identifying genetic factors linked to unexpected infant deaths

  This study is trying to find new genetic links to sudden infant death syndrome (SIDS) by looking at the DNA of babies who have died unexpectedly and their parents.

  Recruiting at 14 sites Nantes University Hospital · Nantes, Loire-Atlantique and 17 other locations · NCT06244433

• Minimizing Tacrolimus in Low Immunological Risk Kidney Transplant Patients

  This study is testing if reducing the use of Tacrolimus, a medication for kidney transplant patients at low risk of rejection, is safe and helps keep their kidney function stable compared to the usual treatment.

  Recruiting Phase 3 Nantes University Hospital · Nantes and 2 other locations · NCT06235892

• Understanding ADHD and addiction in patients

  This study is trying to learn more about how ADHD and addiction happen together in people by collecting information from patients over a year to see how well treatments work.

  Recruiting at 3 sites Nantes University Hospital · Nantes, Loire-Atlantique and 2 other locations · NCT06232226

• Patient safety in coordinated primary care teams: testing a learning system to help MSPs

  This study tests a learning system that helps Maisons de Santé Pluriprofessionnelles improve patient safety by reporting incidents and using linked training and analysis tools.

  Recruiting Nantes University Hospital · Nantes, France · NCT06230341

• Comparing Amoxicillin and Amoxicillin/Clavulanate for Pneumonia in Older Adults

  This study is testing whether amoxicillin works just as well as a combination of amoxicillin and clavulanate for treating pneumonia in older adults who are hospitalized.

  Recruiting at 19 sites Phase 3 Nantes University Hospital · Saint-Nazaire, France and 18 other locations · NCT06229288

• Understanding Patient Views on Reducing Medications in Advanced Cancer Care

  This study is trying to understand how patients with advanced cancer feel about reducing their medications to see what factors influence their thoughts on this process.

  Recruiting Nantes University Hospital · La Roche-sur-Yon and 7 other locations · NCT06193083

• Impact of Plant-Based Diets During Pregnancy on Health Outcomes

  This study is looking at how eating a plant-based diet during pregnancy affects the health of mothers and their babies.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT06155344

• Creating a database to understand the effects of KCNH2 gene variants in Long QT Syndrome

  This study is trying to create a database to help understand how changes in the KCNH2 gene affect people with Long QT Syndrome and improve their diagnosis and treatment.

  Recruiting at 2 sites Nantes University Hospital · Nantes, Loire-atlantique and 1 other locations · NCT06087367

• Premorbid Personality Profile in bvFTD, phFTD, frontal AD, and bipolar disorder

  This study tests whether premorbid personality traits help explain social and behavioral changes in people with bvFTD, phFTD, frontal variant Alzheimer’s, or bipolar disorder.

  Recruiting Nantes University Hospital · Nantes · NCT06059313

• Investigating the Role of Gut Microbiota in Anorexia Nervosa

  This study is testing how the bacteria in the gut might affect weight gain fears and fat distribution in people with severe anorexia nervosa during their recovery.

  Recruiting Nantes University Hospital · Nantes · NCT06043154

• Evaluating the effectiveness of capsaicin patches for chronic coccyx pain

  This study is testing if an 8% capsaicin patch can help people with chronic tailbone pain feel better compared to a lower concentration patch.

  Recruiting at 6 sites Phase 3 Nantes University Hospital · Brest and 5 other locations · NCT06023706

• Indoor environment assessment to help manage fibrosing hypersensitivity pneumonitis

  Aiming to see if an indoor environmental assessment by a specialized advisor can help manage fibrosing hypersensitivity pneumonitis in adults through home visits, antigen testing, and follow-up checks.

  Recruiting at 5 sites Nantes University Hospital · Nantes, Loire-Atlantique and 6 other locations · NCT05988437

• Capsaicin 8% Patch for Coccygodynia: Real‑World Pain Relief Observations

  This study looks at whether a capsaicin 8% patch helps reduce pain in people with coccyx pain when used in real-world care.

  Recruiting Nantes University Hospital · Nantes · NCT05983263

• Treatment of anal fistulas using stem cells

  This study is testing if a new stem cell treatment can help people with complex anal fistulas caused by Crohn's disease feel better after surgery.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT05974280

• Exploring the Enteric Nervous System in Spinal Cord Injury Patients

  This study is trying to understand how spinal cord injuries affect the gut's nervous system and its ability to function properly, in hopes of finding better treatments for digestive issues in these patients.

  Recruiting Nantes University Hospital · Nantes and 1 other locations · NCT05954845

• Collection of blood samples to study inflammation in psychiatric disorders

  This study is trying to see if blood samples from people with psychiatric disorders like schizoaffective disorder and bipolar disorder can help us understand inflammation and improve diagnosis and treatment.

  Recruiting Nantes University Hospital · Nantes · NCT05934474

• Comparing two treatment regimens for adults with acute myeloid leukemia before stem cell transplant

  This study is testing if a treatment using Clofarabine helps adults with acute myeloid leukemia live longer after a stem cell transplant compared to another treatment with Fludarabine.

  Recruiting at 20 sites Phase 2 Nantes University Hospital · Nantes, Loire Atlantique and 22 other locations · NCT05917405

• Using AI to predict melanoma treatment response based on skin damage

  This study is testing if an AI can help predict how well people with advanced melanoma will respond to a specific treatment by looking at their skin damage from sun exposure.

  Recruiting at 4 sites Nantes University Hospital · Besançon, Bourgogne-Franche-Comté and 19 other locations · NCT05856565

• Collaborative GP-Pharmacist Approach to Tapering Benzodiazepines in Older Adults

  This study tests whether a GP-pharmacist collaboration and pharmacist-led motivational interviewing can help people aged 65 and older reduce or stop benzodiazepines prescribed for anxiety or sleep.

  Recruiting Nantes University Hospital · Nantes · NCT05765656

• Daratumumab with induction chemo in older adults with poor-risk AML

  This study tests whether giving daratumumab together with standard induction chemotherapy is safe and helps older adults with poor-prognosis AML reach an effective dose.

  Recruiting Phase 1 Nantes University Hospital · Nantes · NCT05749276

• Using a connected watch to monitor heart rhythm after cardiac surgery

  This study is testing if a connected watch can help monitor heart rhythm in patients who have had heart surgery and experienced irregular heartbeats afterward.

  Recruiting Nantes University Hospital · Nantes, Loire Atlantique · NCT05664308

• Using belatacept instead of CNIs for kidney transplant patients with early graft dysfunction

  This study is testing if belatacept can safely replace standard medications for kidney transplant patients who are having early problems with their new kidney.

  Recruiting Phase 3 Nantes University Hospital · Nantes, Loire Atlantique · NCT05562869

• Nalmefene treatment for craving in behavioral addictions

  This study is testing if nalmefene can help adults with behavioral addictions, like gambling or food issues, by reducing their cravings compared to a placebo.

  Recruiting at 10 sites Phase 3 Nantes University Hospital · Besançon and 12 other locations · NCT05540288

• Impact of air pollution on asthma exacerbations

  This study looks at how air pollution affects asthma patients by tracking their exposure to pollutants at home and outside to see if it leads to more asthma attacks.

  Recruiting Nantes University Hospital · Nantes · NCT05525169

• Linking a hip-worn smartphone gait sensor with spinal MRI in people with multiple sclerosis

  This project will try whether combining a hip-worn IMU smartphone app and routine spinal MRI can better describe walking changes in adults with multiple sclerosis.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT05482906

• Observational study on outcomes of parathyroidectomy in primary hyperparathyroidism

  This study looks at how surgery for primary hyperparathyroidism affects patients' heart, kidney, and bone health, as well as their quality of life, over several years.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT05469087

• Hybrid PET-MR imaging for characterizing arrhythmogenic cardiomyopathies

  This study is testing a new imaging tool to see if it can help doctors better understand the heart issues in patients with arrhythmogenic cardiomyopathies.

  Recruiting at 5 sites Nantes University Hospital · Angers and 4 other locations · NCT05450783

• Medullary stimulation for treating severe neck pain

  This study is testing a new spinal cord stimulation device to see if it can help people with severe neck pain that hasn't responded to other treatments.

  Recruiting Nantes University Hospital · Nantes · NCT05398003

• Follow-up of preterm children during their growth years

  This study is trying to see how being born prematurely affects the growth and health of children aged 8 to 14, especially looking at their body fat and risk for insulin resistance as they get older.

  Recruiting Nantes University Hospital · Nantes · NCT04945369

• Exploring the role of immune cells and gut bacteria in idiopathic nephrotic syndrome

  This study is trying to see how immune cells and gut bacteria affect people with idiopathic nephrotic syndrome during kidney problems.

  Recruiting at 2 sites Nantes University Hospital · Nantes, Loire-Atlantique and 1 other locations · NCT04924712

• Investigating genetic and molecular factors in multiple sclerosis outcomes

  This study is trying to find out how genetic and molecular differences in people with multiple sclerosis can explain why some have a more severe form of the disease than others.

  Recruiting Nantes University Hospital · Nantes, Loire-Atlantique · NCT04873492

• Predicting the growth of unruptured cerebral aneurysms

  This study is trying to see if certain imaging results can help predict how unruptured brain aneurysms grow over time in patients.

  Recruiting at 25 sites Nantes University Hospital · Marseille, Bouches-du-Rhône and 28 other locations · NCT04578808

• Predicting response to Benralizumab in severe asthma patients

  This study is testing if a specific blood test can help predict how well people with severe asthma will respond to the medication Benralizumab.

  Recruiting at 15 sites Phase 4 Nantes University Hospital · Aix-en-Provence and 19 other locations · NCT04565483

• Recovery after heart or chest surgery during the COVID-19 pandemic

  This study will see if adults having cardiac or thoracic surgery who recently had COVID-19 have more postoperative shock, breathing problems, or other organ failures than those without COVID.

  Recruiting Nantes University Hospital · Nantes · NCT04389463

• Cohort of patients with acute hidrosadenitis in the Great West

  This study follows people with acute hidrosadenitis to see how the condition shows up in different ways, which could help improve treatment options.

  Recruiting at 13 sites Nantes University Hospital · Angers and 12 other locations · NCT04352036

• Evaluating a diet low in polyamines to reduce postoperative pain after abdominal surgery

  This study is testing if a special diet low in polyamines can help people having major abdominal surgery feel less pain and need less morphine after their operation.

  Recruiting at 4 sites Nantes University Hospital · Brest and 3 other locations · NCT04219956

• Using Belatacept to Improve Kidney Function in Heart Transplant Patients

  This study is testing if a new medication called belatacept can help protect kidney function in heart transplant patients who are at risk of kidney problems.

  Recruiting at 4 sites Phase 2 Nantes University Hospital · Bordeaux and 3 other locations · NCT04180085

• Infusion of CTL Anti-DP after stem cell transplantation

  This study is testing whether giving special immune cells after a stem cell transplant can help prevent cancer from coming back while reducing side effects for patients with blood cancers.

  Recruiting Phase 1 Nantes University Hospital · Nantes · NCT04180059

• Reducing Cutibacterium Acnes in Shoulder Surgery

  This study is testing if using a benzoyl peroxide cream on the skin for five days before shoulder surgery can help reduce a bacteria that may cause infections in men having shoulder operations.

  Recruiting at 6 sites Phase 3 Nantes University Hospital · Angers and 5 other locations · NCT04028401

• Understanding resistance in multiple myeloma

  This study is trying to understand why some people with multiple myeloma don’t respond to treatment by collecting data and blood samples from patients at specialized cancer centers in Northwestern France.

  Recruiting at 2 sites Nantes University Hospital · La Roche-sur-Yon and 1 other locations · NCT03807128

• Cohort of patients treated for acne at Nantes University Hospital

  This study is looking at first-time acne patients at Nantes University Hospital to see how different factors affect their acne and their quality of life.

  Recruiting Nantes University Hospital · Nantes · NCT03465150

• Database for melanoma patients in France

  This study is creating a database of melanoma patients in France to help researchers and doctors better understand the disease and improve treatment options.

  Recruiting Nantes University Hospital · Nantes · NCT03315468

• Assessing safety and feasibility of cell therapy for early multiple sclerosis

  This study is testing a new cell therapy using immune cells from patients to see if it can help people aged 18 to 45 who are having their first signs of multiple sclerosis.

  Recruiting Phase 1 Nantes University Hospital · Nantes · NCT02912897

• Database for kidney transplantation research

  This study is creating a large database to collect information on kidney transplant patients to help researchers understand their long-term health and improve treatment options.

  Recruiting at 8 sites Nantes University Hospital · Lyon and 7 other locations · NCT02900040

• Observational study on complications of non-traumatic brain injuries

  This study looks at how non-traumatic brain injuries are managed and what complications can arise for people dealing with these conditions.

  Recruiting at 6 sites Nantes University Hospital · Angers and 5 other locations · NCT02714387

• Observational study on complications from severe trauma

  This study looks at how severe trauma affects patients in the ICU to see what complications arise and how to better manage these serious injuries.

  Recruiting at 5 sites Nantes University Hospital · Angers and 4 other locations · NCT02426255

• Understanding behavioral addictions in patients seeking treatment

  This study looks at what influences people with behavioral addictions who are seeking treatment to see how their backgrounds and thoughts affect their recovery.

  Recruiting Nantes University Hospital · Nantes · NCT01248767

Quick answers

How many clinical trials run by Nantes University Hospital are recruiting right now?

144, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in France (144 trials), Guadeloupe (3 trials), Spain (2 trials), Netherlands (1 trial), Switzerland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 13, Phase 2: 8, Phase 1: 4, Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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