Capsaicin 8% Patch for Coccygodynia: Real‑World Pain Relief Observations
Official title: Neuropathic Determining Factors and Analgesic Efficacy of Capsaicin 8% (QUTENZA®) Patches in Refractory Coccygodygnia
Run by Nantes University Hospital · NCT05983263 · Data updated 2026-11-12
This study looks at whether a capsaicin 8% patch helps reduce pain in people with coccyx pain when used in real-world care.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 106 (estimated) |
| Sponsor | Nantes University Hospital Academic / other |
| Locations | 1 site (Nantes) |
| Status | Recruiting |
| Started | November 8, 2023 |
| Main results expected | March 8, 2027 |
| Study ends | June 8, 2027 |
| Registry record updated | June 23, 2026 |
| Trial ID | NCT05983263 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with coccygodynia who received a topical Capsaicin 8% patch between August 2016 and August 2022 at the participating institution.
✕Probably not a fit
Patients whose coccygodynia is driven predominantly by non-neuropathic mechanisms or who do not respond to topical capsaicin may not experience meaningful benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a retrospective, non-interventional study using anonymized patient data collected over six years to evaluate the analgesic effect of the Capsaicin 8% patch (QUTENZA) on coccygodynia. It also explores neuropathic factors that might predict response to treatment. The analysis focuses on real-world use in a French hospital setting, where first-line therapies are often insufficient and alternatives are limited. Outcomes of interest include changes in pain levels and potential neuropathic determinants of response. The study is conducted at Nantes University Hospital with data from CHU de Nantes and does not involve a prospective intervention beyond usual care.
Why it matters
Potential benefit: If successful, the patch could offer a targeted option to reduce coccyx pain for patients who have not responded to conventional therapies.
How similar studies have gone: There is limited prior research on real-world analgesic efficacy of Capsaicin 8% patches for coccygodynia; this observational work addresses a gap and may build on related neuropathic pain findings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who received topical Capsaicin 8% patch therapy for the treatment of their coccygodygnia between August 2016 and August 2022 Exclusion Criteria: * Patients who have already received 8% Capsaicin patch topical treatment in coccyx area.
Where it's running
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CHU de Nantes
Nantes, France Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Evaluating the effectiveness of capsaicin patches for chronic coccyx pain
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.