Impact of air pollution on asthma exacerbations
Official title: Study of the Impact of Exposure to Outdoor and Indoor Pollutants in Patients With Asthma
Run by Nantes University Hospital · NCT05525169 · Data updated 2026-11-12
This study looks at how air pollution affects asthma patients by tracking their exposure to pollutants at home and outside to see if it leads to more asthma attacks.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 99 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Nantes University Hospital Academic / other |
| Locations | 1 site (Nantes) |
| Status | Recruiting |
| Started | November 15, 2022 |
| Main results expected | November 15, 2026 |
| Study ends | November 15, 2026 |
| Registry record updated | April 17, 2026 |
| Trial ID | NCT05525169 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 with a confirmed asthma diagnosis and a history of at least four exacerbations in the past year.
✕Probably not a fit
Patients who are active smokers or have other significant pulmonary conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to measure the exposure of asthma patients to both outdoor and indoor air pollutants to investigate the potential link between pollutant exposure and the frequency of asthma exacerbations. The study will involve continuous monitoring of air quality in patients' homes and outdoor environments. By analyzing the data collected, researchers hope to identify patterns that could inform better management strategies for asthma exacerbations related to air quality.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of asthma exacerbations related to air pollution.
How similar studies have gone: While there is limited research on continuous monitoring of indoor air quality in asthmatic patients, studies on outdoor air pollution and asthma exacerbations have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient over 18 years of age, * Patient with a confirmed diagnosis of asthma for at least 12 months as defined by the investigator, * Patient with at least 4 asthma exacerbations in the last year * Patient sleeping at least 6 nights per week in the same home Exclusion Criteria: * Patient who is an active smoker or living with an active smoker, * Patient with a diagnosis of COPD, ABPA or associated pulmonary fibrosis, * Patient with an asthma exacerbation within 15 days prior to the inclusion visit, * Patient with known occupational exposure, * Patient living in a dwelling that does not allow the installation of sensors (inability to connect the sensor to the power supply, no location for the outdoor sensor...) * Patient who plans to move in the next 6 months, * Patient with a life expectancy of less than 6 months, * Patient who has someone living in their household also included in EXAP, * Patient who lives in an apartment and does not have a balcony or space for the outdoor sensor, * Pregnant or breastfeeding women,
Where it's running
-
CHU de Nantes
Nantes, France Recruiting
Study contacts
- Principal investigator: François-Xavier Blanc, PU-PH — Nantes University Hospital
- Study coordinator: François-Xavier Blanc, PU-PH
- Email: xavier.blanc@chu-nantes.fr
- Phone: 02 40 16 53 33
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.