Recovery after heart or chest surgery during the COVID-19 pandemic
Official title: Patient Outcome of Cardiac Surgery During the COVID-19 Pandemic ; International Cohort Study
Run by Nantes University Hospital · NCT04389463 · Data updated 2026-11-12
This study will see if adults having cardiac or thoracic surgery who recently had COVID-19 have more postoperative shock, breathing problems, or other organ failures than those without COVID.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 350 (estimated) |
| Sponsor | Nantes University Hospital Academic / other |
| Locations | 1 site (Nantes) |
| Status | Recruiting |
| Started | May 11, 2020 |
| Main results expected | May 11, 2026 |
| Study ends | June 30, 2026 |
| Registry record updated | September 8, 2025 |
| Trial ID | NCT04389463 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (age ≥18) scheduled for cardiac or thoracic surgery who have perioperative SARS‑CoV‑2 PCR testing are the intended participants.
✕Probably not a fit
Minors and people not undergoing cardiac or thoracic surgery, or those without perioperative PCR testing, would not be eligible and are unlikely to benefit directly from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational, non-interventional study at Nantes University Hospital enrolling adults undergoing cardiac or thoracic surgery. It compares patients with a positive SARS‑CoV‑2 PCR in the perioperative period to patients who are PCR-negative before surgery and during the 15 days after surgery, focusing on postoperative hemodynamic failure, respiratory failure, and other organ dysfunction. Data are collected from medical records only and no patient-identifiable information is stored. The goal is to capture real-world perioperative outcomes during the COVID-19 pandemic to help inform clinical management.
Why it matters
Potential benefit: If successful, the results could help clinicians identify and better manage increased risk of postoperative shock, respiratory failure, and organ dysfunction in surgical patients with recent SARS‑CoV‑2 infection.
How similar studies have gone: Other observational reports have reported higher rates of postoperative pulmonary and thrombotic complications in patients with perioperative SARS‑CoV‑2, but findings are variable and high-quality prospective data remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (age ≥18 years) undergoing cardiac or thoracic surgery * With positive PCR in the 5 days before or after cardiac/thoracic surgery. Exclusion Criteria: * Minors
Where it's running
-
University Hospital
Nantes, France Recruiting
Study contacts
- Study coordinator: Mickael VOURC'H, MD
- Email: vourchm@gmail.com
- Phone: 0253482835
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Telemedicine-supported prehabilitation to prepare heart failure patients for cardiac surgery
This trial will see if a telemedicine-supported prehabilitation program helps people with heart failure and high NT-proBNP who are having elective cardiac surgery have fewer complications around the time of surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.