COSCINUS cohort and biocollection for spinal cord injury
Official title: Cohorte COSCINUS - Biocollection COhort in Spinal Cord Injury - Nantes Follow-Up Standardization
Run by Nantes University Hospital · NCT06734000 · Data updated 2026-11-12
This project collects clinical information and blood, urine, and stool samples to see patterns and risk factors in people with spinal cord injury.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 16 Years and up |
| Sex | All |
| Enrollment | 105 (estimated) |
| Sponsor | Nantes University Hospital Academic / other |
| Locations | 1 site (Nantes, Loire-Atlantique) |
| Status | Recruiting |
| Started | December 13, 2024 |
| Main results expected | October 10, 2032 |
| Study ends | October 10, 2032 |
| Registry record updated | September 2, 2026 |
| Trial ID | NCT06734000 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
People with a new spinal cord injury admitted in the initial phase of paraplegia or tetraplegia to the Neurological PRM department at Nantes University Hospital who are covered by social security are eligible to participate.
✕Probably not a fit
Patients who are not covered by social security or who are not treated at Nantes University Hospital are not eligible and therefore would not directly benefit from participation in this cohort.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
COSCINUS is a standardized, longitudinal cohort and biocollection based at Nantes University Hospital that systematically records clinical, demographic, functional, and participation data for people with spinal cord injury. Biological samples (blood, urine, feces) are preserved to enable analyses of the microbiome and biomarkers related to metabolism, inflammation, immunity, and injury severity. Data and samples are collected prospectively at defined time points including the acute phase, admission to the PRM department, six months, discharge, and scheduled follow-up visits (1, 2, 3 years) with additional sampling during complications. The platform combines clinical, epidemiological, biostatistical, and IT expertise to support longitudinal analyses and future research collaborations.
Why it matters
Potential benefit: If successful, this cohort could improve understanding of complication risks and biological markers after spinal cord injury, supporting better prevention and personalized care.
How similar studies have gone: Other longitudinal cohorts and biobanks in spinal cord injury have yielded useful epidemiological and biomarker insights, and COSCINUS applies these established methods at a national-level scale.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All individuals with spinal cord injury admitted to the neurological PRM department of the Nantes University Hospital at the initial phase of development of the paraplegia or tetraplegia could participate, regardless the clinical neurological status. Exclusion Criteria: * Patients not covered by social security.
Where it's running
-
Nantes University Hospital
Nantes, Loire-Atlantique, France Recruiting
Study contacts
- Study coordinator: Brigitte Perrouin Verbe
- Email: bp-prom-regl@chu-nantes.fr
- Phone: +33 2 53 48 28 35
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.