Assessing brain injury in cardiac arrest patients
Early and Objective Assessment of Neurological Prognosis in Cardiac Arrest Patients
Nantes University Hospital · NCT06387225
This study is trying to find a better way to check for brain injuries in patients who have had a cardiac arrest to help decide who needs special treatments to improve their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 608 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Nantes University Hospital (other) |
| Locations | 4 sites (La Roche-sur-Yon and 3 other locations) |
| Trial ID | NCT06387225 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the early and objective assessment of neurological prognosis in patients who have suffered out-of-hospital cardiac arrest and are admitted to intensive care. It aims to identify cerebral lesions that could indicate the need for neuroprotective interventions, which are crucial for improving patient outcomes. By utilizing various assessment tools, the study seeks to establish a precise and reproducible method for evaluating the severity of brain injuries upon admission. This approach could help prioritize treatment for patients with significant neurological damage while avoiding unnecessary interventions for those without such lesions.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are comatose upon admission to intensive care following an out-of-hospital cardiac arrest.
Not a fit: Patients who experience in-hospital cardiac arrest or are under 18 years of age may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more targeted and effective neuroprotective treatments for cardiac arrest patients, potentially improving survival and recovery rates.
How similar studies have performed: While there is limited research in this specific area, the study's focus on early neurological assessment in cardiac arrest patients is a novel approach that could fill an important gap in current medical knowledge.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Admitted to intensive care with out-of-hospital cardiac arrest * Comatose on admission (defined by a Glasgow score ≤ 8) * Informed relative who has consented to the patient's participation in the study or inclusion under emergency procedure if the relative is absent at the time of inclusion Exclusion Criteria: * In-hospital cardiac arrest * Age \< 18 years * Person under guardianship or legal protection * Prior inclusion in the study
Where this trial is running
La Roche-sur-Yon and 3 other locations
- CHD Vendée — La Roche-sur-Yon, France (RECRUITING)
- CHU Nantes — Nantes, France (RECRUITING)
- APHP - Hôpital Cochin — Paris, France (RECRUITING)
- CH Saint-Nazaire — Saint-Nazaire, France (RECRUITING)
Study contacts
- Study coordinator: Jean-Baptiste LASCARROU
- Email: jeanbaptiste.lascarrou@chu-nantes.fr
- Phone: 0240087386
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cardiac Arrest, Neurologic Symptoms, Intensive Care Neurological Disorder