Ultrasound to measure muscle quality and fat in older adults during rehab
Official title: Clinical Relevance of Matrix-based Ultrasound Assessment of Intramuscular Fat Infiltration in Hospitalized Older Adults (FATUS-OLD)
Run by Nantes University Hospital · NCT07411547 · Data updated 2026-11-12
We’re testing an ultrasound-based method to see if higher intramuscular fat at the start predicts poorer recovery in physical function for older adults 75+ undergoing rehab.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 75 Years and up |
| Sex | All |
| Enrollment | 115 (estimated) |
| Sponsor | Nantes University Hospital Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Nantes) |
| Status | Recruiting |
| Started | May 21, 2026 |
| Main results expected | November 21, 2028 |
| Study ends | November 21, 2028 |
| Registry record updated | June 25, 2026 |
| Trial ID | NCT07411547 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 75 and older hospitalized in a rehabilitation day-hospital program for gait or balance issues who can provide informed consent.
✕Probably not a fit
Results may not apply to younger patients, those with moderate to severe neurocognitive disorders, or individuals unable to comply with study procedures.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study uses a CE-marked ultrasound device to quantify muscle volume and intramuscular fat in hospitalized older adults during a rehabilitation day-hospital program. The goal is to determine if baseline fat infiltration in muscles helps predict physical performance at 6 months, beyond muscle size alone. Measurements are taken at baseline and during follow-up, with outcomes including SPPB scores and events like falls or rehospitalization. The study is prospective, monocentric, open-label, and non-randomized, conducted at Nantes University Hospital. It aims to validate ultrasound-derived biomarkers of muscle quality in a real-world geriatric population.
Why it matters
Potential benefit: If successful, clinicians could use ultrasound biomarkers to better predict recovery and tailor interventions for older adults at risk of poor physical recovery.
How similar studies have gone: Previous work in this area suggests muscle quality measures can relate to outcomes, but this study explores a novel ultrasound multiparametric approach in a real-world geriatric setting.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 75 years * Hospitalized in rehabilitation day-hospital program * Written informed consent Exclusion Criteria: * Moderate to severe neurocognitive disorders * Inability to comply with study procedures
Where it's running
-
CHU de Nantes
Nantes, France Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.