Cohort study of patients with Inflammatory Bowel Disease in Nantes
Cohorte Nantaise de Maladies Inflammatoires Chroniques Intestinales
This study is trying to collect samples from patients with Inflammatory Bowel Disease to see if they can find new signs that help guide better treatments over the next year.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 360 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Nantes University Hospital Academic / other |
| Locations | 3 sites (Nantes and 2 other locations) |
| Trial ID | NCT06256393 on ClinicalTrials.gov |
What this trial studies
The CELESTE cohort is a prospective observational study involving patients with Inflammatory Bowel Diseases (IBD) at three centers in Nantes. It aims to create a biobank of biological samples from patients with active disease, ranging from those new to treatment to those resistant to multiple therapies. The study will follow these patients over one year to identify new cellular and molecular signatures that could indicate successful therapeutic strategies.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 with an established diagnosis of active IBD requiring surgery or endoscopy.
Not a fit: Patients with quiescent IBD or those who refuse participation will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for patients with Inflammatory Bowel Diseases.
How similar studies have performed: Similar cohort studies have shown promise in identifying biomarkers for treatment success, suggesting potential for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 18 years of age; * Patients with an established diagnosis of IBD: CD, UC, unclassified IBD or refractory chronic pouchitis; * Patients with active disease requiring surgery or endoscopy, whether performed at diagnosis or prior to initiation of new therapy; * Patients who have given written consent to participate in the study and to keep biological samples for research purposes Exclusion Criteria: * Patients refusing to participate in the cohort; * Patients with chronic inflammatory bowel disease quiescent at inclusion; * Patients with a contraindication to general anaesthesia; * Vulnerable patients (under court protection, curators, guardians);
Where this trial is running
Nantes and 2 other locations
- CHU de Nantes — Nantes, France (Recruiting)
- Clinique Jules Verne — Nantes, France (Not_yet_recruiting)
- Hopital Privé du Confluent — Nantes, France (Not_yet_recruiting)
Study contacts
- Study coordinator: Catherine Le Berre, MD
- Email: catherine.leberre@chu-nantes.fr
- Phone: +33240083152
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.