Predicting blockages in external ventricular drains for ICU patients
Official title: Identification of Patients at Risk of Undesired Obstruction in External Ventricular Drain: Development of a Score Based on the Extent of Intra-ventricular Hemorrhage. A Single-Center, Prospective Observational Study.
Run by Nantes University Hospital · NCT06466811 · Data updated 2026-11-12
This study is trying to find out which ICU patients with external ventricular drains are at higher risk for blockages after bleeding in the brain, to help improve their care.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 640 (estimated) |
| Sponsor | Nantes University Hospital Academic / other |
| Locations | 1 site (Nantes, Loire-Atlantique) |
| Status | Recruiting |
| Started | July 4, 2024 |
| Main results expected | December 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | July 12, 2024 |
| Trial ID | NCT06466811 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old who are admitted to the ICU and have had their first EVD inserted within the last 12 hours.
✕Probably not a fit
Patients who are moribund, have intentionally occluded EVDs, or are pregnant or breastfeeding may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to identify high-risk patients for obstruction in external ventricular drains (EVD) following intraventricular hemorrhage (IVH). It focuses on patients admitted to the intensive care unit who have had an EVD inserted within the last 12 hours. The study will analyze brain imaging data to determine the association between IVH and the risk of EVD obstruction, with the goal of improving monitoring and treatment strategies for affected patients.
Why it matters
Potential benefit: If successful, this study could lead to better management of patients with EVDs, reducing complications and improving outcomes in those with intraventricular hemorrhage.
How similar studies have gone: While the specific association between IVH and EVD obstruction remains unproven, similar studies in related fields have shown promise in improving patient outcomes through better monitoring.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria : Patient older than 18 years old, * admitted to the ICU, * with first EVD inserted for less than 12 hours, * and brain imaging (CT or MRI) available in the timespan "24 hours before to 24 hours after" the EVD insertion. Exclusion Criteria : * EVD intentionally occluded immediately after its insertion, * purulent cerebrospinal fluid * Pregnant or breast-feeding patient * Moribund patient or patient with decision of withholding or withdrawing life-sustaining treatment within the 12 hours * Patient with no health insurance * Patient under guardianship
Where it's running
-
Nantes University Hospital
Nantes, Loire-Atlantique, France Recruiting
Study contacts
- Study coordinator: Karim LAKHAL, PH
- Email: karim.lakhal@chu-nantes.fr
- Phone: 33 2 53 48 27 85
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.