Condition

Chronic Kidney Diseases clinical trials and research

• 112Clinical trials
• 6NIH research projects
• 40Countries

Newest Chronic Kidney Diseases clinical trials

All recruiting trials (112)

• Clinical decision support to help consider SGLT2 inhibitors after AKI in type 2 diabetes

  This pilot test checks if a CDS message given to clinicians can help decide whether to consider SGLT2 inhibitors for adults with type 2 diabetes who recently had acute kidney injury.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT07868666

• Impact of TAVR on kidney function in people with aortic valve disease

  This registry tests how trans-catheter aortic valve implantation affects kidney function and the risk of kidney injury in adults with aortic stenosis.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma, RM · NCT07626710

• Calciphylaxis in people with chronic kidney disease: causes, risks, and early signs

  This project will compare adults with chronic kidney disease who develop calciphylaxis to matched CKD patients who do not, collecting clinical data and biological samples to try to find risk factors and early signs.

  Recruiting Odense University Hospital · Odense · NCT07511283

• Oral Semaglutide for CKD and MAFLD in adults with diabetes

  This study tests whether adding oral semaglutide to standard care can slow kidney and liver disease progression in adults with CKD and MAFLD who have type 2 diabetes.

  Recruiting Institute of Liver and Biliary Sciences, India · New Delhi, National Capital Territory of Delhi · NCT07391267

• Eye-brain-kidney connections in chronic kidney disease

  This study will see if changes in brain network connectivity and retinal blood vessels are linked to cognitive decline and kidney function in adults with chronic kidney disease.

  Recruiting Beijing Friendship Hospital · Beijing, Beijing Municipality · NCT07358572

• Screening for chronic kidney disease

  We will see how common chronic kidney disease is among adults followed at a tertiary care center and how many cases were previously undiagnosed.

  Recruiting Institute for Clinical and Experimental Medicine · Prague · NCT07153432

• Streamlined renal denervation with Spyral for uncontrolled high blood pressure

  This trial will test whether a shorter, simpler renal denervation procedure using the Symplicity Spyral system can lower blood pressure in adults with uncontrolled hypertension.

  Recruiting at 20 sites Medtronic Vascular · Melbourne and 20 other locations · NCT07115953

• Empagliflozin in very low eGFR with chronic kidney disease

  This study tests whether empagliflozin can help people with advanced kidney disease and type 2 diabetes who have very low kidney function by reducing kidney protein leakage and potentially protecting kidney function.

  Recruiting Phase 4 Centre Hospitalier Universitaire de Nice · Nice, Alpes-Maritimes · NCT07074418

• Remimazolam infusion for adults undergoing kidney transplant

  This will test whether a continuous remimazolam infusion gives consistent sedation and predictable blood levels in adults having kidney transplants.

  Recruiting Phase 1 Qianfoshan Hospital · Jinan, Shangdong · NCT07045467

• Skin sodium buildup and outcomes in people with chronic kidney disease

  This project will test whether skin sodium levels change with different diets, medicines, and water intake and whether those levels link to kidney and heart outcomes in adults with chronic kidney disease (eGFR 15–60).

  Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Amsterdam-Zuidoost, North Holland · NCT07020104

• Exploring the relationship between gut microbiome and cachexia in chronic kidney disease patients

  This study looks at how the gut bacteria might affect weight loss and muscle wasting in people with chronic kidney disease who are on dialysis.

  Recruiting Université Catholique de Louvain · Brussels and 1 other locations · NCT06986265

• Physical function and strength in children with chronic kidney failure

  Researchers will test whether children aged 8–18 with chronic kidney failure have weaker grip and cough strength, lower physical activity, poorer sleep, and reduced quality of life compared with healthy peers.

  Recruiting Izmir Democracy University · Izmir · NCT06981585

• Outcomes for people with chronic kidney disease and obstructive sleep apnea

  This project will see if obstructive sleep apnea is linked to worse kidney outcomes and identify risk factors in adults with stage 3–4 chronic kidney disease who are not on dialysis.

  Recruiting Nanfang Hospital, Southern Medical University · Guangzhou, Guangdong · NCT06971874

• Personalized approaches to prevent non-communicable diseases in Kazakhstan

  This study is trying to see if analyzing DNA can help create personalized health plans to prevent diseases like heart problems and diabetes for people in Kazakhstan.

  Recruiting Asfendiyarov Kazakh National Medical University · Almaty, Kazakhstan · NCT06953180

• Ear-based vagus nerve stimulation for people with stage 3–5 chronic kidney disease

  This trial will test whether noninvasive ear-based vagus nerve stimulation is safe, tolerable, and can improve autonomic nervous system function in adults with stage 3–5 chronic kidney disease.

  Recruiting NYU Langone Health · New York, New York · NCT06927024

• Gemini multi-organ denervation for uncontrolled high blood pressure

  The Gemini System is being tested to see if multi-organ denervation is safe and can lower blood pressure in adults with uncontrolled hypertension, with or without high cardiovascular risk.

  Recruiting at 18 sites Medtronic Vascular · Stanford, California and 17 other locations · NCT06907147

• Assessing kidney function using electrical impedance tomography

  This study is testing a new portable device that uses electrical signals to create images of the kidneys, helping doctors better understand and monitor chronic kidney disease.

  Recruiting The University of Hong Kong · Hong Kong · NCT06898294

• NAVIGATE Kidney program to reduce gaps in care for people with advanced CKD

  This project will test whether a community health worker–led NAVIGATE-Kidney program helps adults with advanced CKD (eGFR 15–29) start kidney replacement treatment more safely and avoid early catheter use or premature death.

  Recruiting University of Colorado, Denver · Denver, Colorado and 1 other locations · NCT06810622

• Using stem cells to treat chronic kidney disease

  This study is testing whether a single infusion of stem cells can be safely given to people with chronic kidney disease to see how well they tolerate it.

  Recruiting Mayo Clinic · Jacksonville, Florida · NCT06752577

• Examining the effects of furosemide on toxin levels in chronic kidney disease patients

  This study is testing whether the diuretic furosemide affects the levels of certain toxins in the blood and urine of people with chronic kidney disease.

  Recruiting UMC Utrecht · Utrecht, Utrecht · NCT06750575

• Improving physical function in older adults with advanced chronic kidney disease

  We will try a 12-week high-velocity resistance training program to see if it safely improves muscle power and physical function in mobility-limited older adults with advanced chronic kidney disease.

  Recruiting Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT06738394

• HAPA-based health behavior program for adults with metabolic syndrome and chronic kidney disease

  A two-arm study will test a theory-based behavior-change program to see if it improves waist size, kidney function, and related health behaviors in adults with metabolic syndrome and chronic kidney disease.

  Recruiting Chinese University of Hong Kong · Chengdu, Sichuan · NCT06715735

• Comparing two diabetes medications, empagliflozin and dapagliflozin

  This study is testing which diabetes medication, empagliflozin or dapagliflozin, works better for people with type 2 diabetes, chronic kidney disease, and heart failure.

  Recruiting at 12 sites Phase 4 Herlev and Gentofte Hospital · Copenhagen and 11 other locations · NCT06642272

• Increasing daily physical activity for teens with chronic kidney disease

  This 12-week program will test if an online physical-activity plan can add about 15 minutes of moderate-to-vigorous activity per day for adolescents (ages 13–18) with chronic kidney disease.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT06624358

• Evaluating the safety of difelikefalin for itchy skin in adolescents on dialysis

  This study is testing if a new medication called difelikefalin can safely help relieve itching in teenagers aged 12 to 17 who are on dialysis for kidney disease.

  Recruiting at 18 sites Phase 2 Vifor Fresenius Medical Care Renal Pharma · Chengdu and 17 other locations · NCT06593392

• Maintaining RAASi Treatment with Optimal Potassium Control

  This study is testing if adding a new medication can help people with chronic kidney disease safely continue their heart and blood pressure treatments without raising their potassium levels too high.

  Recruiting at 5 sites Phase 3 Fundación para la Investigación del Hospital Clínico de Valencia · Alicante and 4 other locations · NCT06578533

• Optimizing heart failure treatment in elderly patients with kidney issues

  This study is testing if a new medication can help older patients with heart failure and kidney problems safely take higher doses of their heart medications without raising potassium levels too much.

  Recruiting at 3 sites Phase 3 Fundación para la Investigación del Hospital Clínico de Valencia · Alcorcón, Madrid and 5 other locations · NCT06578078

• Specialized oral supplement for improving nutrition in chronic kidney disease

  This study is testing a special nutritional shake and counseling to see if it can help people with chronic kidney disease who aren't on dialysis feel better and improve their nutrition.

  Recruiting NIN Institute · Guadalajara, Jalisco · NCT06576479

• New methods to measure kidney function in patients with chronic kidney disease

  This study is testing new ways to measure kidney function in people with chronic kidney disease to see if they can better predict future problems and how a medication might help.

  Recruiting King's College Hospital NHS Trust · London · NCT06572215

• Using ultrasound to guide heart procedures in patients with kidney disease

  This study is testing if using ultrasound to guide heart procedures can help people with kidney disease have better results than the traditional method.

  Recruiting First Affiliated Hospital Xi'an Jiaotong University · Xi'an, Shaanxi · NCT06567938

• Effects of Dapagliflozin on Kidney Health After Transplant

  This study is testing if the medication dapagliflozin can help improve kidney health in people who have recently had a kidney transplant.

  Recruiting Phase 4 University of Erlangen-Nürnberg Medical School · Erlangen, Bavaria · NCT06560801

• Health behavior change plan for adults with metabolic syndrome and kidney disease

  A 40-person study will test a theory-based behavior-change program to see if it can reduce waist size and protect kidney function over three months in Chinese adults with metabolic syndrome and chronic kidney disease.

  Recruiting Chinese University of Hong Kong · Chengdu, Sichuan · NCT06527768

• Protecting kidney function using remote ischemic conditioning in chronic kidney disease patients

  This study is testing if a new method called remote ischemic conditioning can help protect kidney function in people with chronic kidney disease.

  Recruiting Chinese PLA General Hospital · Beijing, Beijing Municipality · NCT06501222

• Evaluating T-cell response in patients with chronic kidney disease

  This study is trying to understand how the immune system works in patients with end-stage kidney disease to see if improving T-cell function can help reduce their risk of infections.

  Recruiting Centre Hospitalier Régional d'Orléans · Orléans · NCT06474169

• Automated insulin delivery for adults with advanced kidney disease.

  This tries an automated insulin delivery system (Medtronic 780G) with continuous glucose monitoring in adults with type 1 or insulin-treated type 2 diabetes and advanced kidney disease to see if it improves glucose control and quality of life.

  Recruiting Imperial College London · London · NCT06463483

• Quality of life during the transition to home versus in-center dialysis

  This project will see if people with advanced CKD who start home dialysis have better quality of life and less frailty over the first year than those who start in-center hemodialysis.

  Recruiting Ciusss de L'Est de l'Île de Montréal · Montreal, Quebec · NCT06458322

• Testing a medication for children with chronic kidney disease

  This study is testing if a new kidney medication can help children with chronic kidney disease feel better and improve their health over three months.

  Recruiting Early Phase 1 Ann & Robert H Lurie Children's Hospital of Chicago · Chicago, Illinois · NCT06430684

• Helping older patients with kidney disease make treatment decisions

  This study is testing which type of support helps older patients with kidney disease make better treatment choices, either through a kidney educator or a decision-support specialist.

  Recruiting at 5 sites University of Rochester · Brockport, New York and 4 other locations · NCT06410144

• Comparing anticoagulants for patients with atrial fibrillation and severe kidney disease

  This study is testing whether different blood-thinning medications can help people with atrial fibrillation and severe kidney disease stay healthier and avoid complications.

  Recruiting at 2 sites Phase 4 Hospital Sirio-Libanes · Salvador, Estado de Bahia and 5 other locations · NCT06402851

• Assessing cardiovascular and kidney health using metabolomics in patients with heart disease

  This study is testing if certain fat-related substances in the blood can help predict health outcomes for adults with both heart disease and kidney problems.

  Recruiting China-Japan Friendship Hospital · Beijing, Beijing Municipality · NCT06383208

• Investigating biomarkers for kidney obstruction in young children

  This study is trying to find specific markers in urine and blood that can help doctors better diagnose kidney blockages in young children who need surgery.

  Recruiting at 4 sites University of Campania Luigi Vanvitelli · Naples, Campania and 4 other locations · NCT06382233

• Pharmacy-led intervention to improve medication adherence after hospital discharge

  This study tests a pharmacy-led program to help low-income patients with multiple chronic conditions take their medications correctly after leaving the hospital.

  Recruiting University of Tennessee · Knoxville, Tennessee and 1 other locations · NCT06374277

• Nurse-led care for patients with chronic kidney disease

  This study is testing whether a nurse-led care program can help people with chronic kidney disease manage their health better and improve their quality of life compared to regular doctor-led care.

  Recruiting Alexandra Hospital · Singapore · NCT06372743

• Reducing surgical bleeding in adults with advanced or acute kidney disease

  This trial will test whether giving tranexamic acid or desmopressin before noncardiac surgery reduces bleeding in adults with advanced chronic kidney disease or recent acute kidney injury, including those on dialysis.

  Recruiting at 2 sites Phase 3 Hamilton Health Sciences Corporation · London, Ontario and 2 other locations · NCT06337838

• Investigating kidney involvement in Fabry disease using MRI

  This study is testing a new MRI method to see how Fabry disease affects kidney function by looking at oxygen levels in the kidneys compared to healthy individuals.

  Recruiting Copenhagen University Hospital, Rigshospitalet · Copenhagen · NCT06325488

• Personalized diagnosis strategy for rare kidney diseases

  This study is testing a new personalized approach to diagnose rare kidney diseases in patients with certain symptoms to see if it can improve accuracy and help with better treatment options.

  Recruiting at 3 sites Meyer Children's Hospital IRCCS · Florence and 2 other locations · NCT06324136

• Program to reduce unnecessary medications for patients with chronic kidney disease

  This study is testing a program that helps people with chronic kidney disease in Qatar reduce unnecessary medications to see if it improves their health and quality of life.

  Recruiting Hamad Medical Corporation · Doha · NCT06324045

• Lowering blood pressure and cholesterol to improve kidney health in advanced chronic kidney disease

  This study is testing if better control of blood pressure and cholesterol can help adults with advanced kidney disease feel better and slow down the progression of their condition.

  Recruiting Yonsei University · Seoul · NCT06322056

• Examining a new wearable dialysis device for kidney disease patients

  This study is testing a new wearable dialysis device for people with end-stage kidney disease to see if it works better and is safe compared to regular dialysis methods.

  Recruiting UMC Utrecht · Modena, Modena and 2 other locations · NCT06314503

• Effects of green propolis extract and royal jelly on hypertension and chronic kidney disease

  This study is testing if a combination of green propolis extract and royal jelly can help people with high blood pressure and chronic kidney disease feel better.

  Recruiting at 2 sites Universidade Federal Fluminense · Rio de Janeiro, Rio de Janeiro and 1 other locations · NCT06288204

• Beetroot juice and exercise for patients with chronic kidney disease

  This study is testing if drinking beetroot juice along with exercise can help improve health for people with chronic kidney disease.

  Recruiting Universidade Federal Fluminense · Rio de Janeiro, Rio de Janeiro · NCT06286748

• Low protein diet combined with dapagliflozin for chronic kidney disease in type 2 diabetes patients

  This study is testing if a low protein diet combined with the medication dapagliflozin can help people with type 2 diabetes and chronic kidney disease slow down their kidney problems.

  Recruiting Phase 4 Anemia Working Group Romania · Bucharest · NCT06281899

• Digital counseling for chronic kidney disease self-care and education

  This study is testing a digital counseling program to see if it can help people with severe chronic kidney disease take better care of themselves and choose home dialysis options compared to regular care.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT06274710

• Using patiromer to improve blood pressure treatment in chronic kidney disease

  This study is testing if a medication called patiromer can help improve blood pressure treatment for people with chronic kidney disease by making another medication work better.

  Recruiting Phase 4 University Medical Center Groningen · Groningen · NCT06256991

• Low-intensity shock wave therapy for chronic kidney disease and hypertension

  This study is testing if low-intensity shock wave therapy can help people with high blood pressure and chronic kidney disease feel better and improve their kidney function.

  Recruiting Centre Hospitalier Universitaire Vaudois · Lausanne, Canton of Vaud · NCT06194591

• Using SGLT2 inhibitors to treat lupus nephritis in patients with chronic kidney disease

  This study is testing if the medication dapagliflozin can improve kidney function in people with lupus nephritis and chronic kidney disease who are already receiving standard treatment.

  Recruiting Phase 2 The University of Hong Kong · Hong Kong · NCT06155604

• Evaluating kidney and blood pressure outcomes in childhood cancer survivors

  This study is trying to see how common kidney problems and high blood pressure are in childhood cancer survivors a few years after their treatment.

  Recruiting The Hospital for Sick Children · Toronto, Ontario · NCT06153147

• Effects of equol on vascular function in women with and without chronic kidney disease

  This study is testing if taking equol can improve blood vessel health in postmenopausal women, both with and without chronic kidney disease.

  Recruiting Phase 2 University of Colorado, Denver · Aurora, Colorado · NCT06128278

• Impact of Empagliflozin on Kidney Health in African American Veterans

  This study is testing if empagliflozin can help protect kidney health in African American veterans with non-diabetic kidney disease by looking at certain proteins in their urine.

  Recruiting Phase 4 Washington D.C. Veterans Affairs Medical Center · Washington D.C., District of Columbia · NCT06110130

• Psychological treatment for patients with chronic kidney disease

  This study is testing whether Acceptance and Commitment Therapy can help improve the mental well-being of people with chronic kidney disease who are on hemodialysis.

  Recruiting Universidad Europea de Madrid · Madrid · NCT06109493

• Investigating treatments for chronic kidney disease

  This study is testing different treatments for chronic kidney disease to see which ones can help slow down the disease and prevent kidney failure.

  Recruiting at 49 sites Phase 3 The George Institute · Garran, Australian Capital Territory and 50 other locations · NCT06058585

• App to support post-hospital care for people with multiple chronic conditions

  This trial will test a smartphone/tablet app to help people aged 55+ with heart failure, diabetes, or chronic kidney disease manage their care after leaving the hospital.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT06051058

• SelfWrap-Assisted Arteriovenous Fistulas for Chronic Kidney Disease

  This study is testing if a new wrap called SelfWrap can make it safer and more effective for people with chronic kidney disease to have a new arteriovenous fistula created.

  Recruiting at 28 sites VenoStent · Bullhead City, Arizona and 27 other locations · NCT06001827

• Comparing home and in-center dialysis for patients with advanced kidney disease

  This study looks at how switching to dialysis at home or in a hospital affects the quality of life and health of adults with advanced kidney disease over a year.

  Recruiting Ciusss de L'Est de l'Île de Montréal · Montreal, Quebec · NCT05989659

• Evaluating Vitamin K2's Role in Chronic Kidney Disease

  This study is testing if adding Vitamin K2 to the blood pressure medication ramipril can help people with chronic kidney disease feel better and improve their health over six months.

  Recruiting Phase 4 Tanta University · Tanta, Capital of Gharbia Governorate. · NCT05942053

• Evaluating Coenzyme Q10 for Chronic Kidney Disease Management

  This study is testing if adding Coenzyme Q10 to the usual treatment can help people with chronic kidney disease feel better and improve their kidney health.

  Recruiting Phase 4 Tanta University · Tanta, Capital of Gharbia Governorate. · NCT05942027

• Long-term follow-up for patients who received REACT injections for kidney disease

  This study is looking at how safe and effective REACT injections are for people with chronic kidney disease over a five-year period.

  Recruiting Prokidney · Meridian, Idaho · NCT05918523

• Understanding chronic kidney disease in Sub-Saharan Africa

  This study is trying to understand how common chronic kidney disease is in Sub-Saharan Africa and what factors might be causing it by looking at the health and lifestyle of adults in the Bagamoyo district.

  Recruiting Swiss Tropical & Public Health Institute · Bagamoyo, Pwani Region · NCT05881447

• Using microRNA to improve treatment for renal osteodystrophy

  This study is testing if a new method using microRNA can help doctors better understand bone health in people with chronic kidney disease and improve their treatment for renal osteodystrophy.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT05880914

• Evaluating GORE® ACUSEAL Vascular Graft for Dialysis Access

  This study is testing a new type of vascular graft to see if it is safe and effective for people with kidney failure who need access for hemodialysis.

  Recruiting at 3 sites W.L.Gore & Associates · Bielefeld and 3 other locations · NCT05846581

• Using advanced imaging to analyze kidney biopsies for better diagnosis of kidney conditions

  This study is testing a new imaging technique to see if it can help doctors diagnose kidney problems more accurately and quickly in adults who need a biopsy.

  Recruiting Centre Hospitalier William Morey - Chalon sur Saône · Chalon-sur-Saône, Saône-et-Loire · NCT05728216

• Understanding challenges and support for African American adults with kidney disease and diabetes

  This study looks at the challenges and support African American adults with kidney disease and diabetes face to see how it affects their health and how to help them take better care of themselves.

  Recruiting Medical College of Wisconsin · Milwaukee, Wisconsin · NCT05692388

• Using apixaban to prevent strokes in patients with severe kidney disease and atrial fibrillation

  This study is testing if the blood thinner apixaban can help prevent strokes in people with severe kidney disease and atrial fibrillation.

  Recruiting at 29 sites Phase 3 Region Stockholm · Helsinki and 33 other locations · NCT05679024

• Genetic testing for kidney disease risk in African Americans

  This study is trying to see if knowing about certain genetic risks for kidney disease helps African Americans with high blood pressure take better care of their health.

  Recruiting St. Louis University · St Louis, Missouri · NCT05656261

• Impact of home-based walking on cognitive function in older adults with kidney disease

  This study is testing if a 6-month walking program at home can help older adults with kidney disease and memory problems improve their brain function and memory.

  Recruiting at 2 sites Columbia University · Washington D.C., District of Columbia and 1 other locations · NCT05655325

• Observational study on chronic kidney disease in Alsace

  This study is trying to learn more about adults with severe chronic kidney disease in Alsace to see what factors affect their health and how to better manage their condition before they need dialysis or a transplant.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT05527626

• Inducing immunological tolerance in kidney transplant patients using stem cell infusion

  This study is testing whether giving stem cells from the same donor to kidney transplant patients can help them stop taking their immunosuppressive medications safely.

  Recruiting Phase 1 University of California, Los Angeles · Los Angeles, California · NCT05525507

• Evaluating the safety of Desidustat for treating anemia in chronic kidney disease patients

  This study is testing the long-term safety of a medication called Desidustat for treating anemia in people with chronic kidney disease.

  Recruiting Phase 4 Zydus Lifesciences Limited · Sheikhpura, Bihar · NCT05515367

• Understanding risk factors for chronic kidney disease linked to metabolic diseases

  This study is trying to find out how conditions like high blood pressure, diabetes, and obesity can lead to kidney problems in people with chronic kidney disease.

  Recruiting Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT05476627

• Improving health for Black COVID-19 survivors and their caregivers

  This study is testing a telehealth program to help Black COVID-19 survivors and their caregivers improve their health and manage chronic conditions better.

  Recruiting University of South Carolina · Columbia, South Carolina · NCT05370014

• Investigating dapagliflozin's effects on heart function in chronic kidney disease patients

  This study is testing if the medication dapagliflozin can improve heart function in adults with chronic kidney disease who are already taking certain heart medications.

  Recruiting Phase 2 Herlev and Gentofte Hospital · Copenhagen · NCT05359263

• Understanding muscle loss in chronic kidney disease patients

  This study looks at how chronic kidney disease affects muscle loss in patients, especially those with low kidney function or on dialysis, to better understand this serious issue.

  Recruiting Nanfang Hospital, Southern Medical University · Guangzhou, Guangdong · NCT05353660

• Understanding the molecular causes and risks of kidney and related diseases

  This study is trying to understand the genetic and environmental factors that cause kidney diseases and their complications to help improve treatment and care for people at risk or already diagnosed.

  Recruiting University Hospital, Toulouse · Toulouse · NCT05318196

• Integrated diagnosis and treatment for chronic kidney disease outcomes

  This study is trying to see if a combined approach to diagnosing and treating chronic kidney disease can help patients manage their health better and improve their overall outcomes.

  Recruiting Capital Medical University · Beijing, Beijing Municipality · NCT05242055

• Reducing sedentary behavior in patients with chronic kidney disease and obesity

  This study is testing if a combination of guided exercise and a diabetes medication can help people with chronic kidney disease and obesity sit less and be more active.

  Recruiting at 2 sites Phase 2 University of Utah · Stanford, California and 1 other locations · NCT05173714

• Goal-directed blood pressure, fluid, and urine management to prevent kidney injury after kidney removal

  This will try a targeted plan of fluids, medicines, and forced urine output during surgery to see if it reduces acute kidney injury in adults having a radical nephrectomy or nephroureterectomy.

  Recruiting Peking University First Hospital · Beijing, Beijing Municipality · NCT05149196

• Using sodium bicarbonate to improve muscle health in chronic kidney disease

  This study is testing if sodium bicarbonate can help improve muscle health and endurance in people with chronic kidney disease.

  Recruiting Phase 2 University of California, Davis · Sacramento, California and 1 other locations · NCT04984226

• Understanding Diabetic Kidney Disease in Patients with Type 2 Diabetes

  This study is trying to understand how kidney disease affects people with Type 2 diabetes and macroalbuminuria by looking at their kidney samples and other health markers over 20 years to improve treatment options.

  Recruiting at 13 sites Herlev Hospital · Skejby, Aarhus and 12 other locations · NCT04916132

• High-resistance inspiratory muscle training for managing blood pressure in chronic kidney disease

  This study is testing if a special breathing exercise can help lower blood pressure in older adults with chronic kidney disease who struggle to control their hypertension.

  Recruiting University of Colorado, Denver · Aurora, Colorado · NCT04911491

• Investigating FGF19's role in muscle health for chronic kidney disease patients

  This study is testing if a growth factor called FGF19 can help improve muscle strength and mass in people with chronic kidney disease who are at risk of losing muscle.

  Recruiting Hospices Civils de Lyon · Pierre-Bénite · NCT04896047

• Assessing the impact of KidneyIntelX on managing chronic kidney disease in diabetes patients

  This study tests if the KidneyIntelX tool can help doctors better manage kidney health in people with Type 2 diabetes and chronic kidney disease.

  Recruiting Renalytix AI, Inc. · New York, New York · NCT04802395

• Mobile app to manage swelling in kidney patients

  This study tests a mobile app that helps kidney patients manage swelling by adjusting their diuretic medication and tracking their daily health data.

  Recruiting University of Texas Southwestern Medical Center · Dallas, Texas · NCT04759274

• Effects of Ferric Citrate on Kidney Health in Children

  This study is testing if ferric citrate can help improve kidney health in children aged 6-18 with chronic kidney disease.

  Recruiting at 18 sites Phase 2 University of California, Los Angeles · Los Angeles, California and 19 other locations · NCT04741646

• Comparing anti-platelet therapy durations in kidney disease patients after stent placement

  This study is testing whether taking anti-platelet medication for 6 months instead of 3 months helps people with advanced kidney disease feel better after getting heart stents.

  Recruiting Yonsei University · Seoul · NCT04708587

• Transplanting both a kidney and a bladder at the same time

  This study is testing if it's possible to safely transplant both a kidney and a bladder at the same time in patients who have kidney problems caused by bladder issues.

  Recruiting at 2 sites Early Phase 1 Mayo Clinic · Rochester, Minnesota and 1 other locations · NCT04626167

• Human amniotic-derived mesenchymal stem cell treatment for calciphylaxis

  This will try human amniotic-derived mesenchymal stem cells as a treatment for adults 18–75 who have calciphylaxis, including people with chronic kidney disease whether they are on dialysis or not.

  Recruiting Early Phase 1 The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT04592640

• Examining blood pressure patterns in people at risk for heart disease

  This study looks at daily blood pressure patterns in people at risk for heart disease, especially those with kidney issues, to see how these patterns might help identify who could benefit from specific treatments.

  Recruiting University of Edinburgh · Edinburgh · NCT04522765

• Using parathyroid hormone to treat bone disorder in kidney disease patients

  This study is testing whether a hormone treatment can help improve bone health and reduce fracture risk in patients with chronic kidney disease.

  Recruiting Phase 4 Herlev Hospital · Aalborg and 3 other locations · NCT04522622

• Using colchicine to treat heart issues in chronic kidney disease patients

  This study is testing if colchicine can help reduce heart inflammation in people aged 21 to 80 with chronic kidney disease.

  Recruiting Phase 2 Brigham and Women's Hospital · Boston, Massachusetts · NCT04500665

• Using shear wave elastography to differentiate between acute and chronic kidney disease

  This study is testing if a new imaging technique can help doctors tell the difference between acute kidney injury and chronic kidney disease in patients who come to the emergency room.

  Recruiting National Taiwan University Hospital · Taipei · NCT04404114

• Project to improve understanding and treatment of kidney diseases

  This study is trying to find better ways to understand and treat kidney diseases by looking closely at kidney samples and patient data to help create personalized care plans.

  Recruiting at 13 sites Icahn School of Medicine at Mount Sinai · Tucson, Arizona and 12 other locations · NCT04334707

• Study on chronic kidney disease in American Indian populations

  This study looks at chronic kidney disease and heart problems in American Indians to see what makes their health different and to gather important health information for future research.

  Recruiting at 2 sites University of New Mexico · Phoenix, Arizona and 2 other locations · NCT04185844

• Telemonitoring blood pressure in patients with chronic kidney disease

  This study is testing if using home blood pressure monitoring along with extra support can help people with high blood pressure and chronic kidney disease manage their condition better than standard care.

  Recruiting University of Alberta · Edmonton, Albert · NCT04098354

• Oral iron therapy for children with chronic kidney disease

  This study is testing if giving oral iron supplements to children with chronic kidney disease and mild anemia can help improve their strength, activity levels, and eating habits.

  Recruiting at 2 sites Phase 4 Weill Medical College of Cornell University · New York, New York and 1 other locations · NCT03991169

• Research on health inequality and genetic disparity in cardiovascular diseases

  This study is trying to understand how health differences and genetics affect heart diseases in people from various ethnic backgrounds in the UK to help improve treatments for everyone.

  Recruiting Future Genetics Limited · Wolverhampton, West Midlands · NCT03987633

• Protecting kidneys with a tailored low-protein diet approach for advanced CKD

  This study tests a stepwise, patient-tailored low-protein diet to slow kidney decline and delay dialysis in adults with advanced chronic kidney disease.

  Recruiting at 2 sites Centre Hospitalier le Mans · La Flèche and 1 other locations · NCT03979534

• Assessing the impact of comorbidities on postoperative complications.

  This study looks at how having other health issues affects the chances of complications after abdominal surgery to help doctors better understand and manage risks for their patients.

  Recruiting at 37 sites Russian Federation of Anesthesiologists and Reanimatologists · Arkhangelsk and 37 other locations · NCT03945968

• Korean cohort study for outcomes in chronic kidney disease

  This study is trying to follow a group of people with chronic kidney disease in South Korea for up to 10 years to see how their condition changes and what factors affect their health.

  Recruiting Seoul National University Hospital · Seoul, Jongno-gu · NCT03929900

• Investigating uremic toxins and their effects in chronic kidney disease

  This study looks at how certain harmful substances in the body affect health in people with chronic kidney disease to help improve their care and outcomes.

  Recruiting Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · Shanghai, Shanghai Municipality · NCT03711617

• Hospital-level care delivered at home for acutely ill adults

  This trial tries to deliver hospital-level care at home to adults with sudden illnesses like infections, heart failure, COPD, asthma, or gout flares to see if it's as safe, improves patient experience, and lowers costs.

  Recruiting at 2 sites Brigham and Women's Hospital · Boston, Massachusetts and 1 other locations · NCT03524222

• Biobank for calciphylaxis research

  This study is collecting patient samples to learn more about calciphylaxis, a rare condition that causes painful skin sores, in hopes of finding better treatments.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT03032835

• Detecting kidney disease early in preterm infants

  This study is trying to find early signs of kidney problems in preterm infants to help prevent serious health issues later on.

  Recruiting University of Miami · Miami, Florida · NCT02000895

NIH-funded research (6)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Chronic Kidney Disease of Unknown Cause in Agricultural Communities

  A wide study to find what causes a serious kidney disease that affects workers in farming areas, by looking at people in high-risk regions.

  NIH research Research Triangle Institute · Research Triangle Park, United States · NIH-11526674

• Ubiquitin D as a potential target to help NASH, kidney disease, and liver cancer

  A new approach targets a protein called UBD to help people with fatty liver disease, kidney disease, and liver cancer that can arise from liver disease.

  NIH research Sanford Burnham Prebys Medical Discovery Institute · La Jolla, United States · NIH-11365217

• Understanding Ubiquitin D for Liver and Kidney Diseases

  This project looks at a protein called Ubiquitin D to find new ways to help people with liver conditions like NASH and HCC, and also chronic kidney disease.

  NIH research Sanford Burnham Prebys Medical Discovery Institute · La Jolla, United States · NIH-11176365

• Understanding CKDu in agricultural communities

  This project brings researchers together to find the causes and clues behind chronic kidney disease of unknown cause in farming communities so people affected can get better prevention and care.

  NIH research Research Triangle Institute · Research Triangle Park, United States · NIH-11162338

• Investigating chronic kidney disease in agricultural communities

  This study is looking into chronic kidney disease that affects farming communities, and it aims to find out what causes it and how it develops, so if you're a patient, your health information and samples could really help us learn more about this condition.

  NIH research Research Triangle Institute · Research Triangle Park, United States · NIH-10890138

• Improving kidney health in patients with chronic kidney disease through a systems biology approach.

  This study is looking at how low oxygen levels affect kidney cells in people with chronic kidney disease, and it aims to create a helpful scoring system to better understand how these changes relate to patient outcomes, which could lead to improved treatments for those living with this condition.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10755642

Related topics

Quick answers

How many Chronic Kidney Diseases clinical trials are recruiting right now?

112, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 40 countries. The most sites are in United States (35 trials), China (15 trials), United Kingdom (7 trials), France (7 trials), Canada (7 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 12, Phase 2: 8, Phase 3: 5, Early Phase 1: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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