Understanding risk factors for chronic kidney disease linked to metabolic diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to build a cohort of patients suffering from chronic kidney disease (CKD) caused by metabolic diseases such as hypertension, diabetes, hyperuricemia, and obesity. It will investigate the common pathophysiological mechanisms leading to renal injury, including the activation of the Renin-Angiotensin-Aldosterone System and oxidative stress. By identifying risk factors and potential biomarkers, the study seeks to enhance understanding of CKD progression in the context of metabolic disorders.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The diagnosis of metabolic diseases were confirmed;
* Be able to understand the process of the research;
* Volunteer for participation and be able to sign the informed consent.

Exclusion Criteria:

* Age \<18 yrs or \>80yrs;
* Patients with primary and secondary glomerular diseases
* Patients with other comorbidities that could affect the volume or the components of the kidney, such as renal cysts, polycystic kidney disease, medullary sponge kidney, hydronephrosis, renal artery stenosis, renal vein thrombosis and/or renal tumors;
* Contraindications for MRI examination;
* Pregnant or lactation patients;
* Patients with unstable vital signs, failure of other organs or dysphoria.

Where it's running

• Peking Union Medical College Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Limeng Chen — Peking Union Medical College Hospital
• Study coordinator: Yan Liu
• Email: liuyanpumch@163.com
• Phone: +86-15811568692

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Research on health inequality and genetic disparity in cardiovascular diseases

  This study is trying to understand how health differences and genetics affect heart diseases in people from various ethnic backgrounds in the UK to help improve treatments for everyone.

  Recruiting Future Genetics Limited · Wolverhampton, West Midlands · NCT03987633

• Digital tool for doctors to prescribe exercise for people with cardiovascular risk factors

  This project will test whether a new digital tool helps doctors create personalized exercise plans for adults with cardiovascular risk factors.

  Recruiting at 2 sites University of Connecticut · Farmington, Connecticut and 2 other locations · NCT07238556

• Streamlined renal denervation with Spyral for uncontrolled high blood pressure

  This trial will test whether a shorter, simpler renal denervation procedure using the Symplicity Spyral system can lower blood pressure in adults with uncontrolled hypertension.

  Recruiting at 20 sites Medtronic Vascular · Melbourne and 20 other locations · NCT07115953

• Gemini multi-organ denervation for uncontrolled high blood pressure

  The Gemini System is being tested to see if multi-organ denervation is safe and can lower blood pressure in adults with uncontrolled hypertension, with or without high cardiovascular risk.

  Recruiting at 18 sites Medtronic Vascular · Stanford, California and 17 other locations · NCT06907147

• Investigating body fat distribution and its impact on metabolic diseases in Japanese adults

  This study looks at how the way body fat is distributed affects the risk of metabolic and heart diseases in Japanese adults.

  Recruiting Osaka Metropolitan University · Sakai, Osaka · NCT06694012

• Linking social care with healthcare to help manage chronic diseases

  This trial tests whether pairing patients with trained community health workers can help them get transportation, healthy food, information, and better access to care to improve health in conditions like hypertension, diabetes, and high cholesterol.

  Recruiting at 2 sites University of Arizona · Tucson, Arizona and 1 other locations · NCT07799961

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.