Nurse-led care for patients with chronic kidney disease
A Dual-centre, Two-arm, Open-label Randomized Controlled Trial Comparing an Integrated Collaborative Nurse-led Physician-supported Multimorbid Chronic Kidney Disease Care Model Versus Physician-led Care (INTEGREAT-CKD)
NA · Alexandra Hospital · NCT06372743
This study is testing whether a nurse-led care program can help people with chronic kidney disease manage their health better and improve their quality of life compared to regular doctor-led care.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 220 (estimated) |
| Ages | 21 Years and up |
| Sex | All |
| Sponsor | Alexandra Hospital (other) |
| Locations | 1 site (Singapore) |
| Trial ID | NCT06372743 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates a nurse-led, physician-supported care model for patients with chronic kidney disease (CKD) and multimorbidity. A total of 220 participants will be randomized into either the intervention group, which receives the INTEGREAT-CKD program involving outpatient consultations and community-based monitoring by advanced practice nurses, or the control group receiving standard physician-led care. The study aims to improve self-management skills, quality of life, and health literacy while assessing the cost-effectiveness of this approach over a six-month period.
Who should consider this trial
Good fit: Ideal candidates are adults aged 21 and above with CKD stages 3B and above who have sub-optimally managed health parameters.
Not a fit: Patients who are pregnant, have end-stage kidney disease, or have cognitive impairments will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance the quality of life and self-management skills for patients with chronic kidney disease.
How similar studies have performed: Other studies have shown promise in nurse-led care models for chronic diseases, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria : * Adults aged 21 years and above AND diagnosed with * CKD Stages 3B and above (defined as estimated GFR less than or equal to 44 mL/min/1.73m2 with evidence of kidney damage) AND diagnosed with * one or more of the following sub-optimally managed parameters pertaining to blood pressure control OR, glycemic control OR fluid status management. Exclusion criteria: * Pregnancy * End stage kidney disease * Enrolment in any structured outpatient-based or community-based CKD program for at least six months prior to or during the period of enrolment in the study. * Dementia and/or cognitive impairment
Where this trial is running
Singapore
- Wei Zhen Hong — Singapore, Singapore (RECRUITING)
Study contacts
- Study coordinator: Wei Zhen Hong, MBBS, MRCP, MMed
- Email: wei_zhen_hong@nuhs.edu.sg
- Phone: 97330789
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Chronic Kidney Diseases