Physical function and strength in children with chronic kidney failure
Official title: Comparison of Muscle Strength, Physical Activity, Sleep Quality and Quality of Life Between Children With Chronic Kidney Failure and Healthy Children
Run by Izmir Democracy University · NCT06981585 · Data updated 2026-11-12
Researchers will test whether children aged 8–18 with chronic kidney failure have weaker grip and cough strength, lower physical activity, poorer sleep, and reduced quality of life compared with healthy peers.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 8 Years to 18 Years |
| Sex | All |
| Enrollment | 25 (estimated) |
| Sponsor | Izmir Democracy University Academic / other |
| Locations | 1 site (Izmir) |
| Status | Recruiting |
| Started | August 1, 2025 |
| Main results expected | March 1, 2027 |
| Study ends | March 1, 2027 |
| Registry record updated | November 5, 2026 |
| Trial ID | NCT06981585 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children and adolescents aged 8–18 with clinically stable chronic kidney failure who can cooperate with physical testing and questionnaires are ideal candidates.
✕Probably not a fit
Children with recent kidney transplants, active orthopedic, neurological, cardiovascular, or psychological problems, a history of smoking, or inability to cooperate with measurements are unlikely to benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study compares children and adolescents aged 8–18 with clinically stable chronic kidney disease to age-matched healthy controls on grip strength, cough strength, physical activity, sleep quality, and quality of life. Participants will undergo standardized physical measurements, cough and grip testing, and complete validated questionnaires and activity/sleep assessments. People with recent orthopedic, neurological, cardiovascular, or psychological problems, smokers, or those with a prior kidney transplant are excluded to reduce confounding. The aim is to quantify impairments to inform clinical management and possible rehabilitation strategies for pediatric CKD patients.
Why it matters
Potential benefit: If successful, the findings could identify specific physical and quality-of-life impairments to guide targeted monitoring, rehabilitative interventions, and support for children with chronic kidney disease.
How similar studies have gone: Adult studies have shown muscle weakness and reduced activity in chronic kidney disease, but comparable pediatric data are limited, so this approach is partially supported but not well established in children.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: for Children and Adolescents with Chronic Kidney Failure * Being between the ages of 8-18 * Being clinically stable for at least the last 3 weeks * Having the necessary cooperation for the measurements * Being willing to participate in the study Inclusion Criteria for Healthy Children and Adolescents: * Being between the ages of 8-18, * Having the necessary cooperation for the measurements, * Being willing to participate in the research Exclusion Criteria: for Children and Adolescents with Chronic Kidney Failure * Having any orthopedic, neurological, cardiovascular or psychological problems that may prevent measurements from being taken in the last 6 months * Being a smoker or having quit * Having had a kidney transplant. Exclusion Criteria for Healthy Children and Adolescents: * Having a history of any orthopedic, neurological, cardiovascular or psychological problems that may prevent measurements from being taken in the last 6 months * Having any chronic disease * Being a smoker or having quit smoking
Where it's running
-
İzmir Demokrasi Üniversitesi
Izmir, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Hüseyin Kıran — İzmir Demokrasi Üniversitesi
- Study coordinator: Gülşah Barğı
- Email: gulsahbargi35@gmail.com
- Phone: +90 232 299 0739
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.