Pharmacy-led intervention to improve medication adherence after hospital discharge
Official title: Pharmacy-led Transitions of Care Intervention to Address System-Level Barriers and Improve Medication Adherence in Socioeconomically Disadvantaged Populations
Run by University of Tennessee · NCT06374277 · Data updated 2026-11-12
This study tests a pharmacy-led program to help low-income patients with multiple chronic conditions take their medications correctly after leaving the hospital.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 388 (estimated) |
| Sponsor | University of Tennessee Academic / other |
| Locations | 2 sites (Knoxville, Tennessee and 1 other locations) |
| Status | Recruiting |
| Started | April 6, 2024 |
| Main results expected | December 31, 2027 |
| Study ends | January 31, 2028 |
| Registry record updated | January 29, 2026 |
| Trial ID | NCT06374277 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are Medicaid or uninsured inpatients aged 21 and older with multiple chronic conditions and who are prescribed chronic disease medications.
✕Probably not a fit
Patients who may not benefit from this study include those who are Medicare and Medicaid dual eligible, have active psychosis or substance abuse issues, or whose primary admission reason is related to cancer or acute surgical procedures.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This intervention aims to address medication nonadherence among socioeconomically disadvantaged patients with multiple chronic conditions after they are discharged from the hospital. The Med AAAction intervention will focus on overcoming barriers related to financial constraints, transportation issues, and system-level challenges that hinder access to essential medications. By implementing a pharmacy-led approach, the study seeks to enhance medication management and adherence during the critical transition from hospital to home. The effectiveness of this intervention will be evaluated in terms of its impact on medication adherence and subsequent health outcomes.
Why it matters
Potential benefit: If successful, this intervention could significantly improve medication adherence and health outcomes for patients with chronic conditions, reducing readmissions and healthcare costs.
How similar studies have gone: Other studies have shown mixed results with similar approaches, indicating a need for innovative interventions like this one to effectively improve medication adherence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Medicaid or uninsured inpatients * 21 years or older * ≥2 of the complex chronic conditions during index admission or prescribed/using ≥2 chronic medications for these conditions * Patients receiving chronic disease medications from the hospital pharmacy. * Patients will be eligible if they have multiple complex chronic conditions including diabetes, hypertension, high cholesterol, coronary artery disease, congestive heart failure, chronic lung disease, chronic kidney disease, arrhythmia, stroke, psychiatric disorders including depression and anxiety, or who are prescribed or using anticoagulants. Exclusion Criteria: * Medicare and Medicaid dual eligible patients. * If the primary reason for the index admission is related to cancer, pregnancy, or a surgical procedure for an acute problem * If patients have diagnoses of active psychosis, substance abuse, or suicidal ideation during the index admission. * If the planned discharge location is not home. * If patients are part of an existing pharmacy discharge program.
Where it's running
-
University of Tennessee Health Science Center/Regional One Health
Memphis, Tennessee, United States Recruiting -
University of Tennessee Medical Center
Knoxville, Tennessee, United States Not yet recruiting
Study contacts
- Principal investigator: Satya Surbhi, PhD — Uthsc
- Study coordinator: Satya Surbhi, PhD
- Email: ssurbhi@uthsc.edu
- Phone: 646-438-0919
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.