Using advanced imaging to analyze kidney biopsies for better diagnosis of kidney conditions
Official title: Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical Coherence Tomography, a Comparison to Conventional Histopathological Findings for the Diagnosis of Either Acute Kidney Injury or Chronic Kidney Disease in Routine Practices
Run by Centre Hospitalier William Morey - Chalon sur Saône · NCT05728216 · Data updated 2026-11-12
This study is testing a new imaging technique to see if it can help doctors diagnose kidney problems more accurately and quickly in adults who need a biopsy.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Centre Hospitalier William Morey - Chalon sur Saône Academic / other |
| Locations | 1 site (Chalon-sur-Saône, Saône-et-Loire) |
| Status | Recruiting |
| Started | November 1, 2022 |
| Main results expected | October 31, 2028 |
| Study ends | November 30, 2028 |
| Registry record updated | March 18, 2026 |
| Trial ID | NCT05728216 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old with suspected acute kidney injury or chronic kidney disease requiring a biopsy.
✕Probably not a fit
Patients who are unable to undergo dynamic full-field optical coherence tomography during their kidney biopsy will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of dynamic full-field optical coherence tomography in analyzing kidney biopsies to diagnose acute kidney injury and chronic kidney disease. By comparing this advanced imaging technique with conventional histopathological methods, the study aims to enhance the accuracy and speed of kidney disease diagnosis. The research involves patients over 18 years old who require a biopsy due to suspected kidney issues, focusing on improving clinical practices in nephrology. The study is observational and does not involve any experimental treatments.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate and timely diagnoses of kidney diseases, improving patient management and outcomes.
How similar studies have gone: While the use of advanced imaging techniques in pathology is gaining traction, this specific application of dynamic full-field optical coherence tomography for kidney biopsies is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients \> 18 years of age with suspected acute kidney injury requiring biopsy in the nephrology department * patients \> 18 years of age with suspected chronic kidney disease requiring biopsy in the nephrology department Exclusion Criteria: * inability to perform dynamic full-field optical coherence tomography observation at the moment of kidney biopsy
Where it's running
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Centre Hospitalier William Morey - Chalon sur Saône
Chalon-sur-Saône, Saône-et-Loire, France Recruiting
Study contacts
- Principal investigator: Thomas Maldiney — Centre Hospitalier William Morey - Chalon sur Saône
- Study coordinator: Thomas Maldiney
- Email: thomas.maldiney@ch-chalon71.fr
- Phone: +33 3 85 91 01 11
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.