Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Program to reduce unnecessary medications for patients with chronic kidney disease

Official title: Development and Evaluation of a Multidisciplinary Team Delivered Deprescribing Intervention for Patients With Chronic Kidney Disease in Qatar: A Randomized Controlled Trial

Run by Hamad Medical Corporation · NCT06324045 · Data updated 2026-11-12

This study is testing a program that helps people with chronic kidney disease in Qatar reduce unnecessary medications to see if it improves their health and quality of life.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment424 (estimated)
SponsorHamad Medical Corporation
Industry-sponsored
Locations1 site (Doha)
StatusRecruiting
StartedFebruary 19, 2024
Main results expectedDecember 2025
Study endsMarch 2026
Registry record updatedOctober 1, 2025
Trial IDNCT06324045 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this program are patients diagnosed with end-stage renal disease receiving hemodialysis or pre-dialysis patients followed at a low clearance clinic in Qatar.

Probably not a fit

Patients who are critically ill, have psychiatric conditions, or a limited life expectancy of less than six months may not benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This program aims to address the issue of polypharmacy among patients with chronic kidney disease (CKD) in Qatar by implementing a multidisciplinary deprescribing intervention. The approach involves systematically stopping or adjusting medications to improve clinical outcomes and reduce treatment burden. The study will evaluate the effectiveness of this intervention on patient health and quality of life, while also conducting a cost-benefit analysis to assess its economic viability for healthcare systems. By focusing on a collaborative approach, the program seeks to provide strong evidence for the benefits of deprescribing in CKD management.

Why it matters

Potential benefit: If successful, this program could significantly improve the quality of life and clinical outcomes for patients with chronic kidney disease by reducing medication burden.

How similar studies have gone: Previous deprescribing initiatives have shown promise in managing polypharmacy in chronic conditions, but this specific multidisciplinary approach is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Patients who are:

* diagnosed with ESRD receiving hemodialysis treatment or pre-dialysis patients who are followed up at a low clearance clinic.
* receiving treatment at one of the ambulatory kidney centers in Qatar for at least two months.
* able to communicate in Arabic and/or English.

Exclusion Criteria:

* Unstable or has a psychiatric condition.
* Presents with uncontrolled behaviors or exit-seeking behaviors (i.e., seeking to leave the premises out of confusion, frustration, or anger).
* Critically ill patients, pregnant women, children, mentally ill, dementia, and unconscious patients.
* Patients with limited life expectancy (less than 6 months).

Where it's running

  • Hamad Medical Corporation
    Doha, Qatar
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.