Understanding muscle loss in chronic kidney disease patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on the relationship between chronic kidney disease (CKD) and sarcopenia, a condition characterized by the loss of muscle mass and function. It aims to identify the prevalence and contributing factors of sarcopenia in CKD patients, particularly those with an estimated glomerular filtration rate (eGFR) below 60 ml/min/1.73m² or those on maintenance dialysis. By analyzing the impact of uremic toxins, inflammation, and other factors on muscle health, the study seeks to enhance understanding of this serious complication in CKD. No interventions will be administered, as the study is observational in nature.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1.aged ≥18 years and \<80 years 2.eGFR\<60ml/min/1.73m2 or had received maintenance dialysis for at least 3 months.

Exclusion Criteria:

* 1.Patients with neuromuscular diseases: such as muscular dystrophy, amyotrophic lateral sclerosis, spinal cord injury, stroke, and myasthenia gravis; 2.Patients with neurodegenerative diseases: such as Alzheimer's disease, Parkinson's disease and Huntington's disease; 3.patients with advanced malignant tumors; 4.Patients with acute infectious diseases in the past 3 months; 5. Patients with serious cardiovascular or cerebrovascular disease; 6.Moderate to severe edema; 7.Patients with rheumatoid arthritis, multiple sclerosis, or acute gout that limit joint mobility; 8.Pregnant ; 9.Patients identified to be unsuitable for enrollment by the study physician

Where it's running

• Nanfang Hospital, Southern Medical University
  Guangzhou, Guangdong, China Recruiting

Study contacts

• Study coordinator: Min Liang, MD
• Email: nfyylm@163.com
• Phone: +86-20-61686217

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.