Biobank for calciphylaxis research
Partners Calciphylaxis Biobank and Patient Registry
This study is collecting patient samples to learn more about calciphylaxis, a rare condition that causes painful skin sores, in hopes of finding better treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Massachusetts General Hospital Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Trial ID | NCT03032835 on ClinicalTrials.gov |
What this trial studies
The Partners Calciphylaxis Biobank aims to enhance understanding of calciphylaxis, a rare vascular calcification disorder, by collecting and storing patient samples. This observational study focuses on identifying the pathophysiology and risk factors associated with calciphylaxis, which currently lacks effective treatment options. By collaborating with the Partners Biobank, the study will utilize existing infrastructure to support patient consent and sample collection, thereby addressing significant gaps in calciphylaxis research.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older with skin lesions indicative of calciphylaxis.
Not a fit: Patients under 18 years of age or those who are prisoners will not benefit from this study.
Why it matters
Potential benefit: If successful, this biobank could lead to improved understanding and potential future treatments for patients suffering from calciphylaxis.
How similar studies have performed: While calciphylaxis is a rare condition with limited research, the collaborative biobank approach has shown promise in other rare disease studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Male or female ≥18 years old 2. Skin lesions consistent with calciphylaxis diagnosis as determined by the treating clinician 3. Informed of the investigational nature of the study and sign written Informed consent OR are eligible for surrogate consent process based on impaired decision making Exclusion Criteria: 1. Patients \<18 years of age 2. Prisoners
Where this trial is running
Boston, Massachusetts
- Massachusetts General Hospital — Boston, Massachusetts, United States (Recruiting)
Study contacts
- Principal investigator: Sagar U Nigwekar, MD, MMSc — Massachusetts General Hospital
- Study coordinator: Sagar U Nigwekar, MD, MMSc
- Email: snigwekar@mgh.harvard.edu
- Phone: 617-726-7872
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.