Investigating uremic toxins and their effects in chronic kidney disease
The Association Between Uremic Toxins and Outcomes and Comorbidities in Patients With CKD
This study looks at how certain harmful substances in the body affect health in people with chronic kidney disease to help improve their care and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Trial ID | NCT03711617 on ClinicalTrials.gov |
What this trial studies
This observational cohort study aims to explore the causes and epidemiology of comorbidities in chronic kidney disease (CKD). It will identify risk factors linked to CKD mortality and examine the relationship between uremic toxins and various health aspects such as inflammation, oxidative stress, and nutritional status. By analyzing these factors, the study seeks to enhance understanding of CKD outcomes and improve patient management.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have been clinically diagnosed with chronic kidney disease.
Not a fit: Patients with acute kidney injury, recent kidney injury, malignancies, or those who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better prognostic tools and treatment strategies for patients with chronic kidney disease.
How similar studies have performed: Other studies have shown success in exploring the relationship between uremic toxins and chronic kidney disease outcomes, indicating that this approach is supported by existing research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age ≥18 years old; * clinically diagnosed with chronic kidney disease, according K/DOQI criteria. Exclusion Criteria: * acute kidney injury * history of kidney injury \<3 months * malignancy * pregnancy * incomplete clinical data
Where this trial is running
Shanghai, Shanghai Municipality
- Shanghai Ninth People's Hospital — Shanghai, Shanghai Municipality, China (Recruiting)
Study contacts
- Study coordinator: Feng Ding, PhD
- Email: dingfeng@sjtu.edu.cn
- Phone: 86-21-53315165
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.