Investigating uremic toxins and their effects in chronic kidney disease
Official title: The Association Between Uremic Toxins and Outcomes and Comorbidities in Patients With CKD
Run by Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · NCT03711617 · Data updated 2026-11-12
This study looks at how certain harmful substances in the body affect health in people with chronic kidney disease to help improve their care and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | May 1, 2018 |
| Main results expected | December 31, 2024 |
| Study ends | December 31, 2024 |
| Registry record updated | December 3, 2024 |
| Trial ID | NCT03711617 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have been clinically diagnosed with chronic kidney disease.
✕Probably not a fit
Patients with acute kidney injury, recent kidney injury, malignancies, or those who are pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cohort study aims to explore the causes and epidemiology of comorbidities in chronic kidney disease (CKD). It will identify risk factors linked to CKD mortality and examine the relationship between uremic toxins and various health aspects such as inflammation, oxidative stress, and nutritional status. By analyzing these factors, the study seeks to enhance understanding of CKD outcomes and improve patient management.
Why it matters
Potential benefit: If successful, this study could lead to better prognostic tools and treatment strategies for patients with chronic kidney disease.
How similar studies have gone: Other studies have shown success in exploring the relationship between uremic toxins and chronic kidney disease outcomes, indicating that this approach is supported by existing research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * age ≥18 years old; * clinically diagnosed with chronic kidney disease, according K/DOQI criteria. Exclusion Criteria: * acute kidney injury * history of kidney injury \<3 months * malignancy * pregnancy * incomplete clinical data
Where it's running
-
Shanghai Ninth People's Hospital
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Study coordinator: Feng Ding, PhD
- Email: dingfeng@sjtu.edu.cn
- Phone: 86-21-53315165
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Screening for chronic kidney disease
We will see how common chronic kidney disease is among adults followed at a tertiary care center and how many cases were previously undiagnosed.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.