Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating uremic toxins and their effects in chronic kidney disease

Official title: The Association Between Uremic Toxins and Outcomes and Comorbidities in Patients With CKD

Run by Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · NCT03711617 · Data updated 2026-11-12

This study looks at how certain harmful substances in the body affect health in people with chronic kidney disease to help improve their care and outcomes.

More Chronic Kidney Diseases trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorShanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Academic / other
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedMay 1, 2018
Main results expectedDecember 31, 2024
Study endsDecember 31, 2024
Registry record updatedDecember 3, 2024
Trial IDNCT03711617 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who have been clinically diagnosed with chronic kidney disease.

Probably not a fit

Patients with acute kidney injury, recent kidney injury, malignancies, or those who are pregnant may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort study aims to explore the causes and epidemiology of comorbidities in chronic kidney disease (CKD). It will identify risk factors linked to CKD mortality and examine the relationship between uremic toxins and various health aspects such as inflammation, oxidative stress, and nutritional status. By analyzing these factors, the study seeks to enhance understanding of CKD outcomes and improve patient management.

Why it matters

Potential benefit: If successful, this study could lead to better prognostic tools and treatment strategies for patients with chronic kidney disease.

How similar studies have gone: Other studies have shown success in exploring the relationship between uremic toxins and chronic kidney disease outcomes, indicating that this approach is supported by existing research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age ≥18 years old;
* clinically diagnosed with chronic kidney disease, according K/DOQI criteria.

Exclusion Criteria:

* acute kidney injury
* history of kidney injury \<3 months
* malignancy
* pregnancy
* incomplete clinical data

Where it's running

  • Shanghai Ninth People's Hospital
    Shanghai, Shanghai Municipality, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.