Comparing home and in-center dialysis for patients with advanced kidney disease
Official title: Transitioning Patients with Advanced Chronic Kidney Disease to Home or In-center Dialysis: Understanding the Experience and Quality of Life for Patients and Their Caregivers
Run by Ciusss de L'Est de l'Île de Montréal · NCT05989659 · Data updated 2026-11-12
This study looks at how switching to dialysis at home or in a hospital affects the quality of life and health of adults with advanced kidney disease over a year.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 420 (estimated) |
| Sponsor | Ciusss de L'Est de l'Île de Montréal Academic / other |
| Locations | 1 site (Montreal, Quebec) |
| Status | Recruiting |
| Started | January 1, 2023 |
| Main results expected | December 30, 2026 |
| Study ends | December 30, 2027 |
| Registry record updated | February 14, 2025 |
| Trial ID | NCT05989659 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with advanced chronic kidney disease who have chosen their dialysis modality and have an estimated glomerular filtration rate of less than 12 mL/min/1.73m2.
✕Probably not a fit
Patients who are oriented toward conservative treatment or those with a planned kidney transplantation within 6 months may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study follows adults with advanced chronic kidney disease who are transitioning to dialysis, either at home or in a hospital setting. It aims to assess changes in patients' quality of life and frailty status before and up to 12 months after starting dialysis. By utilizing a mixed-methods approach, the study will gather both quantitative and qualitative data to understand the experiences of patients and caregivers during this transition. The research will take place across 12 centers in Canada, engaging patients and caregivers actively throughout the process.
Why it matters
Potential benefit: If successful, this study could provide insights that improve the quality of life for patients with advanced kidney disease by informing better dialysis choices.
How similar studies have gone: While there have been studies on dialysis modalities, this specific mixed-methods approach focusing on quality of life and frailty in the transition phase is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Adults followed in advanced CKD clinic, 2. estimated glomerular filtration rate (eGFR) \<12 mL/min/1.73m2 103, 3. Have chosen their dialysis modality, 4. Understand English or French. Exclusion Criteria: 1. Orientation toward conservative treatment, 2. Planned kidney transplantation \< 6 months, 3. Unable to provide consent due to severe cognitive or psychiatric disease, 4. Previous treatment with dialysis \> 3 months, 5. Life expectancy \< 6 months
Where it's running
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Hôpital Maisonneuve-Rosemont
Montreal, Quebec, Canada Recruiting
Study contacts
- Principal investigator: Annie-Claire Nadeau-Fredette, MD — CIUSSS de l'Est-de-l'Ile-de-Montréal
- Study coordinator: Karine Chaussé
- Email: karine.chausse.cemtl@ssss.gouv.qc.ca
- Phone: 514-252-3400
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.