Comparing home and in-center dialysis for patients with advanced kidney disease
Transitioning Patients with Advanced Chronic Kidney Disease to Home or In-center Dialysis: Understanding the Experience and Quality of Life for Patients and Their Caregivers
Ciusss de L'Est de l'Île de Montréal · NCT05989659
This study looks at how switching to dialysis at home or in a hospital affects the quality of life and health of adults with advanced kidney disease over a year.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 420 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Ciusss de L'Est de l'Île de Montréal (other) |
| Locations | 1 site (Montreal, Quebec) |
| Trial ID | NCT05989659 on ClinicalTrials.gov |
What this trial studies
This observational study follows adults with advanced chronic kidney disease who are transitioning to dialysis, either at home or in a hospital setting. It aims to assess changes in patients' quality of life and frailty status before and up to 12 months after starting dialysis. By utilizing a mixed-methods approach, the study will gather both quantitative and qualitative data to understand the experiences of patients and caregivers during this transition. The research will take place across 12 centers in Canada, engaging patients and caregivers actively throughout the process.
Who should consider this trial
Good fit: Ideal candidates are adults with advanced chronic kidney disease who have chosen their dialysis modality and have an estimated glomerular filtration rate of less than 12 mL/min/1.73m2.
Not a fit: Patients who are oriented toward conservative treatment or those with a planned kidney transplantation within 6 months may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights that improve the quality of life for patients with advanced kidney disease by informing better dialysis choices.
How similar studies have performed: While there have been studies on dialysis modalities, this specific mixed-methods approach focusing on quality of life and frailty in the transition phase is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Adults followed in advanced CKD clinic, 2. estimated glomerular filtration rate (eGFR) \<12 mL/min/1.73m2 103, 3. Have chosen their dialysis modality, 4. Understand English or French. Exclusion Criteria: 1. Orientation toward conservative treatment, 2. Planned kidney transplantation \< 6 months, 3. Unable to provide consent due to severe cognitive or psychiatric disease, 4. Previous treatment with dialysis \> 3 months, 5. Life expectancy \< 6 months
Where this trial is running
Montreal, Quebec
- Hôpital Maisonneuve-Rosemont — Montreal, Quebec, Canada (RECRUITING)
Study contacts
- Principal investigator: Annie-Claire Nadeau-Fredette, MD — CIUSSS de l'Est-de-l'Ile-de-Montréal
- Study coordinator: Karine Chaussé
- Email: karine.chausse.cemtl@ssss.gouv.qc.ca
- Phone: 514-252-3400
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Chronic Kidney Diseases, Chronic Kidney Disease, Quality of Life, Frailty, Home Dialysis, Peritoneal Dialysis, Home Hemodialysis, Hemodialysis