Personalized approaches to prevent non-communicable diseases in Kazakhstan
Official title: Epigenetics and Prevention of Non-communicable Diseases in Kazakhstan: a Personalized Approach and Biological Age Prediction
Run by Asfendiyarov Kazakh National Medical University · NCT06953180 · Data updated 2026-11-12
This study is trying to see if analyzing DNA can help create personalized health plans to prevent diseases like heart problems and diabetes for people in Kazakhstan.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 69 Years |
| Sex | All |
| Enrollment | 6720 (estimated) |
| Sponsor | Asfendiyarov Kazakh National Medical University Academic / other |
| Locations | 1 site (Almaty, Kazakhstan) |
| Status | Recruiting |
| Started | March 3, 2025 |
| Main results expected | January 1, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | July 11, 2025 |
| Trial ID | NCT06953180 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 to 69 years residing in Kazakhstan who are willing to participate and provide informed consent.
✕Probably not a fit
Patients outside the age range of 18 to 69 years or those unable to provide informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on enhancing personalized and preventive care for non-communicable diseases (NCDs) in Kazakhstan by investigating epigenetic factors and utilizing machine learning to predict biological age and reproductive function. The study involves DNA analysis to develop tailored health improvement recommendations for participants. By examining the relationship between DNA methylation and various health conditions, the research aims to provide insights into effective prevention strategies for cardiovascular diseases, type 2 diabetes, chronic respiratory diseases, obesity, and chronic kidney diseases.
Why it matters
Potential benefit: If successful, this study could lead to more effective prevention strategies for non-communicable diseases, improving health outcomes for individuals in Kazakhstan.
How similar studies have gone: While the specific approach of combining epigenetics with machine learning in this context may be novel, similar studies have shown promise in understanding the role of genetics in disease prevention.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 to 69 years. * Residents of 17 regions of Kazakhstan. * Willingness to participate and provide informed consent. Exclusion Criteria: * Age less than 18 years old or over 69 years old. * Failure to provide informed consent or incomplete participation in data collection procedures.
Where it's running
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Asfendiyarov Kazakh National Medical University
Almaty, Kazakhstan, Kazakhstan Recruiting
Study contacts
- Study coordinator: Ildar Fakhradiyev, Ph.D
- Email: fakhradiyev.i@kaznmu.kz
- Phone: +7 (727) 338 7090
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.