Personalized approaches to prevent non-communicable diseases in Kazakhstan
Epigenetics and Prevention of Non-communicable Diseases in Kazakhstan: a Personalized Approach and Biological Age Prediction
This study is trying to see if analyzing DNA can help create personalized health plans to prevent diseases like heart problems and diabetes for people in Kazakhstan.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 6720 (estimated) |
| Ages | 18 Years to 69 Years |
| Sex | All |
| Sponsor | Asfendiyarov Kazakh National Medical University Academic / other |
| Locations | 1 site (Almaty, Kazakhstan) |
| Trial ID | NCT06953180 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on enhancing personalized and preventive care for non-communicable diseases (NCDs) in Kazakhstan by investigating epigenetic factors and utilizing machine learning to predict biological age and reproductive function. The study involves DNA analysis to develop tailored health improvement recommendations for participants. By examining the relationship between DNA methylation and various health conditions, the research aims to provide insights into effective prevention strategies for cardiovascular diseases, type 2 diabetes, chronic respiratory diseases, obesity, and chronic kidney diseases.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 69 years residing in Kazakhstan who are willing to participate and provide informed consent.
Not a fit: Patients outside the age range of 18 to 69 years or those unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective prevention strategies for non-communicable diseases, improving health outcomes for individuals in Kazakhstan.
How similar studies have performed: While the specific approach of combining epigenetics with machine learning in this context may be novel, similar studies have shown promise in understanding the role of genetics in disease prevention.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 to 69 years. * Residents of 17 regions of Kazakhstan. * Willingness to participate and provide informed consent. Exclusion Criteria: * Age less than 18 years old or over 69 years old. * Failure to provide informed consent or incomplete participation in data collection procedures.
Where this trial is running
Almaty, Kazakhstan
- Asfendiyarov Kazakh National Medical University — Almaty, Kazakhstan, Kazakhstan (Recruiting)
Study contacts
- Study coordinator: Ildar Fakhradiyev, Ph.D
- Email: fakhradiyev.i@kaznmu.kz
- Phone: +7 (727) 338 7090
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.