Sponsor or institution
Clinical trials and research at University of California, San Diego
As of November 12, 2026, Find a Trial lists 137 clinical trials run by University of California, San Diego that are recruiting, at sites in 8 countries (most in United States (134), Nigeria (2), Botswana (1)). 2 were first registered in the last 30 days. By phase: Phase 2 (19), Phase 4 (11), Phase 1 (9), Phase 3 (5). There are also 1,840 NIH-funded research projects at this institution, with $1.1 billion in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 137Clinical trials
- 1840NIH research projects
- 2New in 30 days
- 8Countries
Newest trials
All recruiting trials (137)
-
Cervical screening and care options for women living with HIV who test positive for high-risk HPV
This study tests different ways to screen and manage high-risk HPV in women with HIV to see what might work best for them.
-
NPT Feasibility in Knee Osteoarthritis
This study tests whether NRPT can be safely given to adults with knee osteoarthritis and whether it shows early signals of benefit.
-
Recovery-oriented suicide prevention for young people at clinical high risk for psychosis
This program tests a peer-supported, clinician-led suicide prevention group for young people at clinical high risk for psychosis to see if it helps reduce suicidal thoughts and support recovery.
-
Anti-inflammatory diet for people with lupus
This study tests whether an anti-inflammatory diet can affect symptoms and biological markers in people with systemic lupus erythematosus who are already taking Cellcept or Mycophenolate.
-
Biomarkers for opioid use and pain response after trauma and surgery
This study tests whether microRNA patterns can predict long-term opioid risk in adults after trauma or surgery.
-
Precision pain management plan using suzetrigine in high-risk surgical patients
In people at high risk for long-term opioid use after surgery, this trial tests whether taking suzetrigine around the time of surgery reduces overall opioid use in the first 14 days postoperatively.
-
Gamma brain-feedback to boost working memory in schizophrenia
This trial tests whether real-time gamma EEG neurofeedback helps people with schizophrenia or schizoaffective disorder improve working memory.
-
Changing the Script multimedia program to support family planning in Nigeria
This project will test whether the Changing the Script multimedia program helps women aged 15–44 and their partners in Kano, Kaduna, and Nasarawa make and act on family planning decisions.
-
Culturally Adapted Pain Management for Indigenous Peoples
A feasibility test will see if a culturally tailored pain-management program can be delivered to AI/AN adults with chronic pain at the Yakama Service Unit and pave the way for a larger trial.
-
Mindfulness‑augmented brain stimulation for treatment‑resistant depression
This trial will test whether combining fast brain stimulation (iTBS) with a digital mindfulness program helps people with treatment‑resistant depression reduce symptoms and improve thinking.
-
Nutritional approaches for college students with depression
This project will test whether a Mediterranean diet, with or without time-restricted eating, is practical and can be followed by college students with mild-to-moderate depression.
-
A Latina-focused program to address nutrition, cravings, and eating patterns to prevent type 2 diabetes
This program will try a culturally adapted 'Regulation of Cues' behavioral approach to help Latinas with prediabetes and obesity lose weight and lower their risk of developing type 2 diabetes.
-
Routine STI screening during pregnancy to improve birth outcomes
This study tests whether adding screening and treatment for chlamydia and gonorrhoea to standard antenatal care can reduce preterm birth and other problems for pregnant women in Botswana.
-
Long-term atrial fibrillation risk after an acute illness
A small implantable heart monitor will be used to see if adults who develop acute atrial fibrillation—especially after cardiac surgery—have more long-term recurrences than those with AF after non-cardiac surgery or medical illness.
-
Aligning daily activities with your circadian rhythm to boost student well-being
This project will try using the Owaves: MyBodyClock app for seven weeks to align daily activities with UCSD undergraduates' natural sleep‑wake preferences and see if it increases happiness, focus, and energy.
-
BPCARE: Community health worker support to improve blood pressure and medication use
This trial will test whether community health workers can help adult refugees with high blood pressure take their medicines and keep their blood pressure under control compared with enhanced usual care.
-
Meditation and interpersonal brain connections in people who use opioids
We will try meditation plus brief psychoeducation with adults who use opioids nearly every day to see if paired meditation increases physiological synchrony and empathic connection and relates to better opioid outcomes.
-
Mindfulness-Enhanced Ketamine Therapy for Opioid Use Disorder
This trial tests whether adding Mindfulness-Oriented Recovery Enhancement (MORE) to Ketamine-Assisted Psychotherapy helps people with opioid use disorder who are on MOUD reduce opioid use and cravings.
-
Shorter androgen deprivation in combination with radiation for high-risk prostate cancer
Doctors are testing whether 6 months of hormone therapy with radiation works as well as 18 months, for men with high-risk prostate cancer.
-
Kawasaki MATCH decision support for suspected Kawasaki disease
This study will test a machine-learning tool called Kawasaki MATCH to help providers decide if febrile children might have Kawasaki disease.
-
Vancomycin given into the joint, into bone, or by IV during total knee replacement
This trial will test whether a single dose of vancomycin injected into the knee joint before a primary total knee replacement protects against infection as well as vancomycin given into bone or by IV for adults treated at UC San Diego.
-
AI-guided selection for who might benefit from a second CDK4/6 inhibitor in advanced HR+ HER2- breast cancer.
This trial will test whether an AI model can pick people with HR+ HER2- advanced breast cancer who may do better if they try a different CDK4/6 inhibitor plus fulvestrant after progressing on their first CDK4/6 inhibitor.
-
How bilinguals control language when listening, speaking, and signing
This project will test whether bilingual adults who use two spoken languages (Mandarin and English) or a spoken and a signed language (ASL and English) can control which language they use when they understand and produce words and signs.
-
SB-4826 for adults with advanced solid tumors or non-Hodgkin lymphoma
This trial tests whether the oral drug SB-4826, given alone or with rituximab, is safe and can help adults with advanced solid tumors or non-Hodgkin lymphoma.
-
Retifanlimab plus ruxolitinib for advanced kidney and lung cancers
This trial will test whether taking ruxolitinib twice daily together with retifanlimab infusions every 4 weeks is safe and can help people with metastatic renal cell carcinoma or non-small cell lung cancer who progressed on prior PD-1/PD-L1 therapy.
-
Gamified mental health app to boost self-compassion in injured adolescent dancers
This project will try a gamified mental health app to increase self-compassion in adolescent dancers recovering from foot or ankle injuries.
-
At-home spaced transcranial direct current stimulation for treatment-resistant depression
This will test whether a two-week program of at-home spaced transcranial direct current stimulation (tDCS) can help people with treatment-resistant depression who have not improved on antidepressants.
-
CHAMPION: Combining HIV Prevention and Meth Treatment for HIV-Negative MSM
This pilot test will see if two mobile health tools can help HIV-negative men who have sex with men who use meth take PrEP more consistently.
-
Long-term effects of time-restricted eating on cardiometabolic health
This 54-week study will test if limiting daily eating to an 8–12 hour window helps adults with metabolic syndrome and pre-diabetes improve blood sugar, cholesterol, blood pressure, and body composition.
-
Imatinib plus fampridine before surgery for KIT exon 11 gastrointestinal stromal tumor
This trial tests whether adding fampridine to standard imatinib before surgery is safe and helps shrink KIT exon 11 mutant GIST tumors in adults.
-
Preparedness through community respiratory virus testing and engagement
This program will offer community members regular testing for respiratory viruses like COVID-19, flu, and RSV and invite some people to join longer-term monitoring and household transmission follow-up.
-
How radiation affects cervical cancer biology and treatment side effects
We will see if radiation therapy changes tissue factor and other molecular markers in women receiving radiation for cervical cancer by collecting blood and tumor samples before, during, and at the end of treatment.
-
iTEST: a blended mobile program to improve introspective accuracy (accurate self-judgment of abilities)
This trial tests whether iTEST — daily mobile cognitive training plus coaching that focuses on accurate self-judgment — helps adults with schizophrenia-spectrum or other psychotic disorders improve community functioning.
-
How male-level testosterone affects reproductive hormone cycles in people assigned female at birth
This study will test whether male-level testosterone given to transgender men starting hormone therapy changes the ovarian and pituitary hormones that control menstrual cycles compared with cisgender women.
-
Whole-food, plant-based diet for endometriosis pain and quality of life
This trial will test whether switching to a whole-food, plant-based diet for 12 weeks helps women with endometriosis have less pain and better quality of life.
-
OneMark implant to help locate breast cancer for surgery and follow-up
This test checks whether the OneMark implant helps surgeons and radiologists see breast cancers more clearly during surgery and during imaging follow-up in adults who have or may have breast cancer.
-
Brain scans and blood tests to spot neurotoxicity after CAR T-cell therapy
This project will try brain MRIs, cognitive tests, and blood biomarkers to see if we can identify which adults receiving CAR T-cell therapy will develop neurotoxicity (ICANS).
-
Video-guided exercise program to help recovery after mastectomy
This 16-week live small-group video exercise program will try to improve fitness, balance, and strength for adults who recently had a mastectomy.
-
Mechanism-guided treatment versus proton-pump inhibitor therapy for chronic throat symptoms
This trial will test whether a mechanism-guided approach combining personalized acid-suppression and voice therapy helps adults (18–89) with chronic throat symptoms more than usual proton pump inhibitor (PPI) treatment.
-
Image-guided tumor-focused radiotherapy for intermediate- and high-risk prostate cancer
This trial will test whether giving higher, tumor-targeted radiation while lowering dose to the rest of the prostate reduces urinary and bowel side effects for people with intermediate- or high-risk prostate cancer receiving curative radiotherapy (with or without systemic therapy).
-
Effect of acetazolamide on kidney function in people with Type 1 Diabetes
This study tests if a medication called acetazolamide can improve kidney function in people with Type 1 Diabetes.
-
Buffered versus unbuffered lidocaine paracervical block to reduce pain and measure clinician empathy during IUD placement.
This will see if buffered or unbuffered lidocaine injections, with or without topical numbing gel, reduce pain and change how much empathy patients feel from clinicians during IUD placement for people aged 18–50 getting an IUD.
-
New method for diagnosing obstructive sleep apnea using muscle activity measurements
This study is trying out a new, painless way to diagnose obstructive sleep apnea by measuring muscle activity in the mouth and throat to see if it can provide accurate results.
-
Maintenance treatment using rTMS for depression
This study is testing if a type of brain treatment called rTMS can help people with hard-to-treat depression stay feeling better after their initial treatment.
-
Time-restricted eating for people with type 2 diabetes and microalbuminuria
This study tests whether following an 8–10 hour daily eating window can improve kidney health in adults with type 2 diabetes and microalbuminuria.
-
Context-aware mobile program to boost social recovery in serious mental illness
This project will test a blended mobile and in-person therapy called mSITE to help adults with schizophrenia or schizoaffective disorder increase how often they interact with other people.
-
Optimizing LDL cholesterol levels using inclisiran for patients with drug interactions
This study is testing if inclisiran can help lower LDL cholesterol in patients with multiple health issues who can't take statins due to other medications.
-
Time-restricted eating plus a healthy diet for people with liver cancer
This trial will try an 8–10 hour time-restricted eating plan together with targeted healthy food changes for overweight adults with early-to-intermediate liver cancer who are having liver-directed therapy.
-
Tranexamic acid to reduce bleeding during second-trimester dilation and evacuation
We will test whether giving prophylactic tranexamic acid before a second-trimester dilation and evacuation reduces bleeding for people aged 18 and older at 18–24 weeks of pregnancy.
-
Psilocybin-assisted therapy to improve physician well-being and reduce burnout
This project will test whether psilocybin-assisted therapy can reduce burnout and improve well-being in physicians at UC San Diego.
-
PRECISE — a personalized suicide-prevention program using daily mood and behavior data
This project will test whether using frequent mood and behavior tracking plus tailored coaching and safety planning can help reduce suicidal thoughts in adults at high risk.
-
Cemiplimab plus gemcitabine for metastatic pancreatic cancer with SWI/SNF gene changes
This trial will test whether adding the immunotherapy cemiplimab to the chemotherapy gemcitabine helps people with metastatic pancreatic ductal adenocarcinoma who have SWI/SNF genetic alterations and have already received one prior chemotherapy regimen.
-
Continuous versus single adductor canal nerve block for outpatient total knee replacement
This test checks whether adding a 5-day continuous adductor canal nerve block to the usual single injection lowers pain and opioid use after outpatient total knee replacement.
-
Using TriCalm Hydrogel® to treat itching caused by immunotherapy
This study is testing if TriCalm Hydrogel® can help reduce itching for cancer patients receiving immunotherapy.
-
Comparing two laser systems for breaking up kidney stones
This study is testing whether a new type of laser for breaking up kidney stones works as well and as quickly as a current laser option during a minimally invasive procedure.
-
Evaluating elranatamab for treating relapsed or refractory multiple myeloma
This study is testing a new treatment called elranatamab to see if it can help people with relapsed or refractory multiple myeloma who have already tried other therapies.
-
Using advanced ultrasound to evaluate liver disease in children
This study is testing new ultrasound methods to see if they can help doctors better detect and monitor liver fat in children at risk for liver disease.
-
Improving mood and sleep in menopausal women using light and sleep adjustments
This study is testing if adjusting sleep schedules and using bright light can help improve mood and sleep for women going through menopause who are feeling depressed.
-
Meditative neurofeedback for treating depression
This study is testing whether a new 10-session meditation program using neurofeedback can help people with major depression feel better.
-
Effect of Dupilumab on Esophageal Muscle Function in Eosinophilic Esophagitis
This study is testing if Dupilumab can help improve the muscle function in the esophagus of people with Eosinophilic Esophagitis.
-
Food referrals to help families of children access healthy produce.
This program will see if clinic screening plus social-worker referrals help families of children with nutrition-related conditions who receive Medicaid or SNAP access affordable healthy food.
-
Comparing full and empty bladder protocols for pelvic radiation therapy
This study is testing whether having a full or empty bladder during pelvic radiation therapy helps deliver the right dose of radiation and reduces side effects for patients with certain cancers.
-
Combining Fostamatinib with Gemcitabine and Nab-paclitaxel for Pancreatic Cancer Treatment
This study is testing if adding a new drug called Fostamatinib to standard chemotherapy can help improve treatment outcomes for patients with operable pancreatic cancer.
-
Neoadjuvant Opdualag (nivolumab + relatlimab) versus nivolumab for resectable high-risk basal cell carcinoma
This trial tests whether adding relatlimab to nivolumab before surgery helps people with resectable high‑risk basal cell carcinoma shrink tumors and improve surgical outcomes.
-
Treatment for oligometastatic cancers using stereotactic ablative radiotherapy
This study is testing if adding a special type of radiation treatment to standard care can help people with a few cancer spread spots live longer and feel better.
-
Exploring how Guselkumab therapy affects liver and joint health in Psoriatic Arthritis patients with NAFLD
This study is testing how a treatment called Guselkumab can help people with Psoriatic Arthritis who also have liver problems, to see if it improves their joint and liver health.
-
Using virtual reality to assess and treat tobacco addiction
This study is testing if a medication called varenicline can help daily tobacco users in San Diego reduce their cravings by using virtual reality to expose them to smoking cues.
-
Evaluating advanced MRI techniques for detecting prostate cancer
This study is testing new MRI techniques to see if they can help doctors better detect significant prostate cancer in men without needing special contrast dyes.
-
Using advanced chest X-ray technology to screen for lung cancer
This study is testing a new type of chest X-ray to see if it can find lung cancer as well as or better than regular CT scans for people being screened for the disease.
-
Investigating brain activity related to decision making in eating disorders
This study is trying to see how the brains of women with anorexia and bulimia react when making decisions about food compared to women without eating disorders.
-
Time-restricted eating intervention for Alzheimer's disease
This study is testing if eating only during a 14-hour window at night can help people with Mild Cognitive Impairment or early Alzheimer's disease think better and sleep more soundly.
-
Ketogenic diet's effects on brain response in individuals recovered from anorexia nervosa
This study is testing if a special ketogenic diet can change how the brains of people who have recovered from anorexia nervosa work, compared to healthy individuals.
-
Using Coenzyme Q10 to help veterans with Gulf War illness
This study is testing if a special form of coenzyme Q10 can help veterans with Gulf War illness feel better and improve their quality of life.
-
Transplanting stem cells to treat Parkinson's disease
This study is testing whether transplanting special stem cells into the brains of people with Parkinson's disease can help improve their symptoms and overall health.
-
Preoperative intestinal training with antegrade ileostomy infusion
This trial will try infusing material from your ostomy bag back into your unused intestine before reversal surgery to see if it helps the bowel recover faster for people with a diverting loop ileostomy.
-
Targeted phage therapy for recurrent urinary infections in women with kidney transplants.
We will test whether targeted bacteriophage therapy can prevent recurrent E. coli urinary infections in adult women who have had a kidney transplant.
-
Effects of a high CBD cannabis extract on pain in Complex Regional Pain Syndrome
This study is testing whether a high CBD cannabis extract can help people with Complex Regional Pain Syndrome find relief from their pain.
-
Using genetics to improve asthma treatment
This study is testing how well two asthma treatments work for people with moderate to severe asthma by looking at their genetic information to see who might benefit the most.
-
Understanding maternal health after preeclampsia
This study is trying to find out how to help new moms who had preeclampsia stay healthy and avoid heart problems after giving birth.
-
Effects of Hypoxic Breathwork
This study is testing how a week of breathing exercises combined with music and positive messages can affect people's health, stress, and sleep.
-
Cognitive training for anxiety, depression, and PTSD
This study is testing a brain training program to see if it can help people with anxiety, depression, or PTSD think more clearly and feel better.
-
Focal therapy for localized prostate cancer treatment
This study looks at how well different focal therapy treatments work for men with localized prostate cancer who have chosen this option, by tracking their progress before and after the procedure.
-
Impact of neurochecks on cognitive outcomes in older patients with brain injury
This study is testing if changing how often older patients with brain injuries get neurological checks in the ICU can help them think better and reduce confusion.
-
Peer support program to improve health for women living with HIV
This study tests a program that combines therapy, exercise, and support from peers to help women living with HIV stick to their medications and improve their overall health.
-
Comparing different treatments for childhood obesity and food responsiveness
This study is testing different treatments for kids aged 7-12 who are overweight and tend to eat more than they need, to see which method helps them manage their eating and lose weight best.
-
Using a CD40 antibody with electroporation to treat advanced pancreatic cancer
This study is testing a new way to treat advanced pancreatic cancer by injecting a special antibody directly into tumors during surgery to see if it helps the immune system fight the cancer better.
-
Improving ADHD treatment through team-based school interventions
This study is testing a new team-based approach to improve a school program for children with ADHD to see if it helps them do better in school.
-
Integrating cervical cancer screening and treatment into HIV care in Nigeria
This study is testing whether adding cervical cancer screening and treatment to HIV care can help women in Nigeria get better health support and stay in treatment.
-
Determining the best time to stop CPAP for premature infants
This study is testing the best time to stop using CPAP for premature babies born very early to see if it helps them breathe better and stay healthy.
-
Impact of an anti-inflammatory diet on knee osteoarthritis
This study is testing if following an anti-inflammatory diet can help people with knee osteoarthritis feel better and improve their symptoms.
-
Peer navigation support for Hispanic parents of children with cancer
This study tests whether having trained peer supporters can help Hispanic parents of children with cancer get involved in clinical trials better than standard care.
-
Time Restricted Eating for Patients with Sleep Apnea
This study is testing if a new eating schedule can help people with sleep apnea improve their metabolism and overall health.
-
Therapeutic ketogenic diet for anorexia nervosa and bulimia nervosa
This 14-week program will try a therapeutic ketogenic diet to see if it helps adults with anorexia nervosa (both weight-recovered and mildly underweight) and a small pilot of people with bulimia nervosa reduce restrictive or binge‑purge behaviors and improve mood and body satisfaction.
-
Investigating the Mediterranean Diet's Effects on Inflammatory Bowel Disease
This study is trying to see if switching to a Mediterranean diet can help people with inflammatory bowel disease feel better and improve their health.
-
Monitoring pregnancy and infant outcomes after tralokinumab exposure
This study looks at how using the medication tralokinumab during pregnancy affects both the pregnancy and the baby's health compared to pregnant individuals with atopic dermatitis who didn't use the drug.
-
Improving early detection of prostate cancer using advanced MRI techniques
This study is testing a new MRI technique to see if it can help doctors find prostate cancer more accurately during biopsies.
-
Observing the natural history of patients with HPDL mutations
This study is trying to learn more about people with HPDL mutations and their related mitochondrial diseases by collecting health information and blood samples to see how these conditions change over time.
-
Using a wearable biopatch to predict readmissions after sepsis
This study is testing if a wearable patch can help predict which patients discharged after sepsis might need to go back to the hospital within 30 days.
-
Using Acetazolamide to Treat Obstructive Sleep Apnea
This study is testing if a medication called acetazolamide can help adults with moderate to severe obstructive sleep apnea breathe better at night and feel more rested during the day.
-
Comparing two surgical methods for ankle syndesmosis injuries
This study is testing which of two surgical methods for fixing ankle injuries works better in helping patients recover and feel less pain.
-
Using 3D Ultrasound to Help Treat Liver Cancer
This study tests if a special 3D ultrasound can help doctors better track how well treatment is working for patients with liver tumors.
-
Combining brain stimulation and cognitive training to treat depression after mild brain injuries
This study is testing if combining brain stimulation with special cognitive training can help people with depression after a mild brain injury feel better.
-
New method for fixing femoral fractures
This study is testing a new type of implant for fixing femur fractures in adults to see if it helps them heal better and have fewer complications.
-
Using TRUMATCH Graft Cage for repairing long bone defects
This study is testing a new device called the TRUMATCH Graft Cage to see if it helps adults with serious bone injuries in their arms or legs heal better and get back to their normal activities.
-
Testing Levetiracetam for treating neonatal seizures
This study is testing how much of the medication Levetiracetam is safe to give to newborns with seizures to see if it works better than the standard treatment.
-
Examining cognitive changes in brain tumor patients receiving radiation therapy
This study is trying to see how radiation therapy affects thinking and memory in people with brain tumors over time, so that doctors can improve treatment and help patients keep their cognitive skills.
-
Effect of an anti-inflammatory diet on knee osteoarthritis
This study is testing whether following an anti-inflammatory diet can help people with knee osteoarthritis feel less pain and improve their joint health.
-
Understanding the benefits of human milk on infant and child health
This study is trying to see how breast milk affects the health of babies and children by collecting milk samples and health information from breastfeeding mothers.
-
Effects of cannabis on the microbiome and inflammation in HIV
This study is testing how cannabis compounds THC and CBD affect gut health and inflammation in people living with HIV.
-
Web-based support for women living with HIV/AIDS
This study is testing a new online support program to see if it can help women living with HIV/AIDS who have faced violence stick to their medication and improve their health.
-
Telehealth support for young cancer patients to preserve fertility
This study tests a new telehealth program to see if it helps young cancer patients get better support and information about preserving their fertility.
-
Effects of Blood Pressure on Thinking and Brain Blood Flow in Parkinson's Disease
This study is testing how low blood pressure affects thinking and blood flow in the brains of people with Parkinson's disease who have trouble standing up.
-
Comparing two types of brain stimulation for reducing suicidal thoughts in patients with treatment-resistant depression
This study is testing two types of brain stimulation to see which one helps reduce suicidal thoughts in people with treatment-resistant depression.
-
Using weighted blankets to reduce pain after breast surgery
This study is testing if using weighted blankets can help reduce anxiety and pain after breast surgery for patients.
-
Effects of THC on glucose metabolism in Type 2 Diabetes
This study is testing whether THC can improve how the body processes sugar and supports heart health in people with Type 2 Diabetes.
-
Investigating the effects of sleep apnea and COPD on heart health
This study is testing how having both sleep apnea and COPD affects heart health and whether a specific breathing treatment works better than oxygen therapy for improving heart outcomes in these patients.
-
Fresh fruit and vegetable prescriptions for families with type 2 diabetes
This study is testing whether giving families with children who have type 2 diabetes vouchers for fresh fruits and vegetables can improve their health and nutrition.
-
Investigating brain function in anorexia and bulimia nervosa
This study is trying to see how the brains of women with anorexia and bulimia respond to rewards compared to healthy women, using brain scans while they do tasks and eat a meal.
-
Measuring vaginal narrowing after radiation treatment for cervical cancer
This study is trying to see how radiation treatment for cervical cancer affects vaginal narrowing in patients, to better understand their experiences and improve future treatments.
-
Evaluating MRI for Prostate Cancer Assessment
This study is testing a new type of MRI scan to see if it can better predict serious prostate cancer in men who already have the disease.
-
Investigating how cannabis helps relieve pain
This study is testing how vaporized cannabis helps relieve pain by looking at how it affects the brain while participants feel controlled heat.
-
Using erector spinae plane block catheters with intrathecal morphine for pain relief after liver surgery
This study is testing if using special catheters for pain relief along with morphine can help people recovering from liver surgery feel less pain and recover faster compared to standard pain management.
-
Impact of an anti-inflammatory diet on rheumatoid arthritis
This study tests if following an anti-inflammatory diet can help people with rheumatoid arthritis feel better and improve their health.
-
Monitoring levodopa levels in Parkinson's disease using a new sensor
This study is testing a new sensor that can measure levodopa levels in real time for people with Parkinson's disease to help improve their treatment and manage symptoms better.
-
Phentermine‑topiramate to help obese adults with active ulcerative colitis
This trial will test whether the weight‑loss medicine phentermine‑topiramate helps obese adults with active ulcerative colitis lose weight and improve their response to biologic treatment over 22 weeks.
-
Treatment for knee osteoarthritis using bone marrow aspirate concentrate
This study is testing whether a treatment using concentrated bone marrow can help people with moderate to severe knee osteoarthritis feel less pain and improve their joint health before they have knee replacement surgery.
-
Using Cannabidiol to Treat Early Psychosis
This study is testing if adding Cannabidiol (CBD) to the usual treatment can help young people and adults with early psychosis feel better and improve their symptoms.
-
Cognitive-sparing radiosurgery for brain metastases
This study is testing a new way to use targeted radiation for patients with brain tumors to see if it can help protect their thinking skills while treating the cancer.
-
Assessing heart damage in young cancer survivors
This study is trying to find out if heart damage can be detected early in young cancer survivors who received certain chemotherapy treatments, to help prevent future heart problems.
-
Observing characteristics and inflammatory markers in children with eosinophilic esophagitis
This study is looking at children with eosinophilic esophagitis to see how their symptoms and lab results relate to inflammation in their bodies.
-
Assessing cognitive function after carotid artery stenting
This study is testing how carotid artery stenting affects thinking and memory in people with narrowed carotid arteries by checking their cognitive skills and brain blood flow before and after the procedure.
-
Evaluating heart transplant dysfunction using MRI and sequencing
This study is testing if heart scans and genetic analysis can help find early signs of problems in heart transplant patients to improve their care.
-
Investigating food aversion in anorexia nervosa patients
This study is testing how people with anorexia nervosa react to food compared to healthy individuals to better understand their food aversions and improve treatment options.
-
Comparing lumbar and extraventricular drains to prevent complications after brain hemorrhage
This study is testing whether using a lumbar drain or an extraventricular drain helps prevent complications in patients who have had a brain hemorrhage.
-
Personalized cancer therapy assessment
This study is trying to see how personalized cancer treatments affect patients' responses and side effects by looking at their medical records and genetic information.
-
Monitoring pregnancy outcomes for women exposed to Stelara and Tremfya
This study is tracking pregnancies in women who have used Stelara or Tremfya to see how these medications might affect the health and development of their babies.
-
Diagnostic innovations for detecting glaucoma in eyes with and without myopia
This project tests imaging and vision tests to see if they can better detect glaucoma or its worsening in adults with or without myopia.
NIH-funded research (newest 40 of 1840)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
-
Improved MRI guidance for pediatric heart catheterization using autonomous multi-beat image synthesis
Aiming to make MRI-guided pediatric heart catheterizations safer and more reliable by using smart, multi-beat data fusion to produce clearer real-time MRI images.
-
Adapting a combination approach to reduce heavy drinking and boost HIV care and prevention among young men
A pilot project tests a proven program that helps young men cut down on heavy drinking and improves HIV treatment and prevention outcomes.
-
How specific anti-NMDAR1 antibodies in the blood may affect memory and brain protection
This research is exploring whether natural or abnormal anti-NMDAR1 antibodies in the blood influence memory, behavior, and brain protection in humans.
-
Screening and treatment of Chlamydia infection in pregnancy to help prevent preterm birth
This grant studies whether screening pregnant people for Chlamydia trachomatis and treating those who are positive can reduce the risk of preterm birth.
-
Pharmacometrics Core at UC San Diego
A pharmacometrics core is funded to support researchers in analyzing drug data to improve how medicines work for patients.
-
Milk Analytics Core for Precision Dairy Research
A core facility at UC San Diego will provide specialized milk analysis services to support research on dairy biology and human health.
-
Data science support for patient-focused research
A patient-facing grant aims to advance data science methods that could improve how medical data about illnesses is used to help people.
-
Clinical care and research collaboration hub (P50) at UC San Diego
A P50 grant from NIH supports a patient-facing research program at UC San Diego to advance clinical care through a coordinated, multi-project effort.
-
Integrated knowledge resource for the human pancreas and Type 1 diabetes
A large NIH grant aims to build a comprehensive, user-friendly knowledge base that combines many data about the human pancreas to help understand and treat Type 1 diabetes.
-
ABCD-USA Coordinating Center for Youth Brain Development Study
A nationwide effort to follow thousands of 9–10 year-olds over many years to learn how youth behaviors, brain development, and environment relate to health and substance use.
-
Cell Maps for AI: Building detailed human cell maps to guide AI in genomics
A project at UCSD is generating complex maps of human cell structure and function to help AI understand how genetic differences lead to health outcomes.
-
Understanding how neurons resist and recover from toxic chemicals
Researchers are studying how brain cells fight back against harmful chemicals to help people survive exposure.
-
IGV tool advances for cancer genomics to help researchers and clinicians
A NIH grant supports keeping the Integrative Genomics Viewer (IGV) up-to-date so cancer researchers and clinicians can visualize and interpret complex genomic data more effectively.
-
Cirrhosis Network study to understand mortality and therapies
A large, multi-center study in people with cirrhosis to find better ways to predict deaths and test the potential of statins to prevent complications like liver cancer and liver failure.
-
AI-powered collaborative data sharing for diabetes research (dkNET Coordinating Unit)
A national effort to build a privacy-preserving, federated AI platform that lets researchers train diabetes-focused AI models across many institutions without sharing patient data.
-
CRISPR-based gene editor to slow Alzheimer's by tweaking APP
A gene-editing approach using CRISPR to modify a specific part of the APP gene in brain cells aims to slow Alzheimer's disease and move toward human trials.
-
Personalized iTBS for Depression: Faster, Targeted Brain Stimulation
A personalized, time-efficient brain stimulation approach may help people with treatment-resistant depression achieve better relief using tailored iTBS settings.
-
Pesticide exposure and fertility health as people move from adolescence to adulthood
This long-term study follows people in Ecuador to see how pesticide exposure over the years relates to fertility and hormones as they become young adults.
-
Maintenance rTMS for depression: keeping relief after response
A study tests whether continuing targeted brain stimulation can help people with treatment-resistant depression stay well after an initial positive response.
-
Microbiome and Innate Immune Response in Alcohol-Related Liver Disease
Researchers are studying how gut bacteria and the body's first-line immune defenses contribute to liver damage from alcohol, with a focus on how a specific bacteria and its toxins affect disease severity.
-
ecDNA in Cancer: Targeting circular cancer DNA to slow tumor growth
A funded project at UCSD aims to understand and target extrachromosomal DNA that drives aggressive cancers, with the goal of slowing tumor growth and improving outcomes for patients.
-
Imaging and EHR data combine to predict ICU outcomes with clinician and patient input
Aims to build a computer model that uses chest X-ray images, doctor notes, and electronic health record data to predict outcomes for ICU patients, with input from clinicians, patients’ families, and ethics experts.
-
Open data commons for stroke research to speed better treatments
A national project to build an open, community-guided data platform so scientists share and reuse preclinical stroke research data to help translate lab findings into effective therapies.
-
How tissue stiffness affects oral cancer spread
A researcher at UC San Diego is studying how the stiffness of mouth tissue influences the behavior of oral cancer cells in people.
-
Accelerating cervical cancer screening for people living with HIV in low-resource settings
A US and Nigerian collaboration tests two practical ways to get more HIV patients screened and treated for cervical cancer, aiming to scale up in low-income and rural areas.
-
Optimizing antibiotic use in breastfeeding mothers and babies through microbiome and metabolomics
A large, patient-focused effort to understand how a mother’s antibiotic treatment affects her breastfed baby’s gut microbiome, immune responses, and vaccine readiness.
-
Bacterial biosensors to detect and help prevent GI cancers
A team is building living bacterial sensors that could detect colorectal and pancreatic tumors inside the gut and give a clear diagnostic signal.
-
Optimizing CBSST with Executive Function Training for Older Adults with Schizophrenia
A team at UC San Diego is testing a combined cognitive behavioral social skills program with executive function training to help older adults with schizophrenia stay functional and independent.
-
How cell receptors control blood-vessel inflammation
This work looks at how certain cell receptors keep signaling from inside cells and how that can cause inflammation in blood vessels for people with vascular conditions.
-
How genetic differences affect how pancreatic beta cells respond to environment
A study in people and lab models will explore how genetic variants influence how pancreatic beta cells change in response to environmental signals that affect insulin release.
-
Healthy Brain and Child Development study network
This grant supports a national effort to map how genes and early-life experiences shape brain development in thousands of children from birth to age 10.
-
Healthy Brain and Child Development: A National Effort to Map Child Neurodevelopment
A large nationwide project will follow thousands of mothers and babies from birth to age ten to understand how genes and the environment shape healthy brain development.
-
Genetics of secretion in yeast
Researchers are studying how yeast cells move and break down parts of their internal plumbing (ER) to recycle materials, which could reveal new biology about cellular housekeeping.
-
Microbiome and Metagenomics Center supports precision health research
A UCSD center helps process stool samples and generate high-quality microbiome data to support precision nutrition health research.
-
Mindfulness-enhanced brain stimulation for depression
This project tests whether combining a breath-focused attention training with targeted brain stimulation helps people with treatment-resistant depression think more clearly and feel better.
-
Ketogenic Diet for Weight-Recovered Anorexia Nervosa to Support Metabolism and Eating-Disorder Symptoms
A research project will test a ketogenic diet to see if it helps people who have recovered weight from anorexia nervosa by normalizing brain metabolism and reducing core eating-disorder thoughts and behaviors.
-
CAUSE: Linking DNA damage to unexplained cancer mutation patterns
A big, AI-powered project that looks at how DNA damage from everyday sources leads to cancer mutation patterns, with the goal of clearer causes and better prevention.
-
Genes linked to opioid use and addiction risk in a large, diverse group
Researchers look for genetic differences that help explain why some people try opioids, react differently, or develop opioid use disorder.
-
How pesticide spray seasons affect thinking and mood in teens and young adults
This project follows teens and young adults for two years to look for short-term changes in thinking skills and mood linked to nearby pesticide spray seasons.
-
How activated protein C helps protect the blood vessel lining
This project looks at how activated protein C helps the cells that line blood vessels stay healthy during conditions like sepsis.
Quick answers
How many clinical trials run by University of California, San Diego are recruiting right now?
137, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 8 countries. The most sites are in United States (134 trials), Nigeria (2 trials), Botswana (1 trial), New Zealand (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 19, Phase 4: 11, Phase 1: 9, Phase 3: 5. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.