Screening and treatment of Chlamydia infection in pregnancy to help prevent preterm birth
Official title: Screening and treatment for Chlamydia trachomatis infection to prevent preterm birth
Funded at University of California, San Diego · NIH-11617691 · Data updated 2026-11-12
This grant studies whether screening pregnant people for Chlamydia trachomatis and treating those who are positive can reduce the risk of preterm birth.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | August 1, 2025 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $108,007 |
| NIH project number | 3R01HD116989-02S2 |
| Project ID | NIH-11617691 on NIH RePORTER |
Who could benefit from this research
✓Could help
Pregnant individuals in LMIC settings (and populations similar to those studied in Botswana) who are screened for CT during antenatal care.
✕Less likely to help
Pregnant individuals without CT infection or who do not access antenatal care may not directly benefit.
What this research studies
Chlamydia trachomatis infection during pregnancy is common and can contribute to preterm birth and other problems for the baby. The project builds on prior Botswana findings showing that screening asymptomatic pregnant people is feasible and may lower infection rates, aiming to determine the effect on birth outcomes through a larger trial. Researchers plan to implement screening and timely treatment in a real-world setting, using a rigorous design to measure impact on preterm birth and related outcomes. The study is focused on improving maternal and infant health in LMIC contexts and could inform future screening guidelines if successful.
Why it matters
Potential benefit: If successful, the approach could reduce preterm births and improve infant health by identifying and treating asymptomatic CT infections during pregnancy.
How similar studies have gone: Prior small studies showed screening is feasible and potentially reduces post-birth CT prevalence, but larger trials are needed to confirm birth outcome benefits.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Wynn, Adriane Michelle — University of California, San Diego
- Study coordinator: Wynn, Adriane Michelle
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.