Examining cognitive changes in brain tumor patients receiving radiation therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to prospectively analyze primary brain tumor patients undergoing fractionated radiation therapy. It will utilize quantitative neuroimaging and neurocognitive testing to assess changes in brain function and structure over time. The goal is to correlate radiation exposure with cognitive outcomes, ultimately informing strategies to minimize cognitive decline associated with treatment. By identifying sensitive brain regions affected by radiation, the study seeks to enhance future radiation techniques for better patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients 18 years or older
2. Karnofsky performance status (KPS) ≥70
3. Life expectancy of ≥1 year
4. Primary brain tumor patients who will receive fractionated partial brain RT
5. Able to complete neurocognitive assessments

Exclusion Criteria:

1. Inability to undergo MRI with contrast
2. Prior brain RT

Where it's running

• Moores Cancer Center
  San Diego, California, United States Recruiting

Study contacts

• Study coordinator: Sheila Medina
• Email: s4medina@health.ucsd.edu
• Phone: 858-822-6575

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.