A Latina-focused program to address nutrition, cravings, and eating patterns to prevent type 2 diabetes
Official title: Reducing Obesity and Risk for Type 2 Diabetes in Latinas Using a Novel Behavioral Strategy Addressing Appetitive Traits
Run by University of California, San Diego · NCT07478263 · Data updated 2026-11-12
This program will try a culturally adapted 'Regulation of Cues' behavioral approach to help Latinas with prediabetes and obesity lose weight and lower their risk of developing type 2 diabetes.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 55 Years |
| Sex | Women only |
| Enrollment | 30 (estimated) |
| Sponsor | University of California, San Diego Academic / other |
| Locations | 1 site (La Jolla, California) |
| Status | Recruiting |
| Started | March 31, 2026 |
| Main results expected | June 30, 2027 |
| Study ends | June 30, 2027 |
| Registry record updated | March 17, 2026 |
| Trial ID | NCT07478263 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are Hispanic/Latina women ages 18–55 with BMI 30–45 kg/m2 and an HbA1c of 5.7–6.4% who can read English or Spanish and have physician approval.
✕Probably not a fit
People with diagnosed type 2 diabetes, current pregnancy or lactation, serious cardiac or psychiatric conditions, active substance use disorder, bulimia, recent psychiatric hospitalization, or those already in weight-loss programs are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial adapts the Regulation of Cues (ROC) program for adult Hispanic/Latina women with prediabetes and BMI 30–45 to teach skills for recognizing hunger and fullness cues, managing cravings, and changing eating patterns. Participants receive the ROC behavioral intervention in Spanish or English and are monitored for changes in weight and blood sugar (HbA1c) to see whether the program reduces progression to type 2 diabetes. Key exclusions include current type 2 diabetes, pregnancy or lactation, serious medical or psychiatric conditions, and current enrollment in other weight-loss programs. The study is conducted at the UCSD Center for Healthy Eating and Activity Research (CHEAR) in La Jolla.
Why it matters
Potential benefit: If successful, this could help Latinas with prediabetes lose weight and reduce their chances of developing type 2 diabetes.
How similar studies have gone: Prior research on cue-based programs like Regulation of Cues has shown promising results for reducing overeating and supporting weight loss, but applying ROC specifically to prevent diabetes in Latinas is relatively new.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women who self-identify as Hispanic/Latina, aged 18-55 * BMI 30-45 kg/m2 * Documented diagnosis of prediabetes also confirmed by HBA1c level of 5.7-6.4% * Spanish or English proficiency at a 5th grade level * Physician approval to participate Exclusion Criteria: * Current diagnosis of T2D * Current Pregnancy or lactation or planning to get pregnant within the study duration * Recent history of heart disease, symptoms of angina, stroke, orthopedic problems that would limit activity during the following 6 months, or any other serious medical condition that would make physical activity unsafe * Currently enrolled in weight-loss program or taking medications for weight loss or prediabetes * Current moderate or severe alcohol or substance use disorder, acute suicidal ideation, psychosis, compensatory behaviors, or a diagnosis of bulimia * Hospitalization due to a psychiatric disorder in the past year. * Planning to move from the San Diego area within the next 6 months
Where it's running
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UCSD Center for Healthy Eating and Activity Research (CHEAR
La Jolla, California, United States Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.