Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Effect of an anti-inflammatory diet on knee osteoarthritis

Official title: Effect of Anti-inflammatory (ITIS) Diet in Knee Osteoarthritis

Run by University of California, San Diego · NCT05559463 · Data updated 2026-11-12

This study is testing whether following an anti-inflammatory diet can help people with knee osteoarthritis feel less pain and improve their joint health.

More Osteoarthritis, Knee trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorUniversity of California, San Diego
Academic / other
Locations1 site (La Jolla, California)
StatusRecruiting
StartedOctober 1, 2021
Main results expectedJanuary 1, 2027
Study endsOctober 1, 2027
Registry record updatedNovember 5, 2026
Trial IDNCT05559463 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals diagnosed with knee osteoarthritis who have not changed their treatment in the last three months.

Probably not a fit

Patients with food allergies or those who are pregnant may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the impact of an anti-inflammatory diet on clinical and biological outcomes in patients suffering from knee osteoarthritis. Researchers will analyze inflammation in the joints and identify specific molecules and bacteria that may predict pain levels in these patients. Blood, urine, and stool samples will be collected and compared before and after dietary changes to gather preliminary data on the effects of diet on inflammation and pain. The goal is to uncover insights that could lead to new therapeutic approaches for managing knee osteoarthritis.

Why it matters

Potential benefit: If successful, this study could provide a dietary approach to reduce pain and improve quality of life for patients with knee osteoarthritis.

How similar studies have gone: While this approach is exploratory, similar studies have shown promise in using dietary interventions to manage inflammatory conditions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients diagnosed of Knee Ostoeaarthritis
* without changes in treatment in the last 3 months

Exclusion Criteria:

* food allergies
* pregnancy

Where it's running

  • UCSD
    La Jolla, California, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.