Clinical trial Recruiting at 1 site Observational Ages 1 Year to 65

Observing characteristics and inflammatory markers in children with eosinophilic esophagitis

Official title: Characteristics and Inflammatory Markers in Children With Eosinophilic Esophagitis (EoE)

Run by University of California, San Diego · NCT03980886 · Data updated 2026-11-12

This study is looking at children with eosinophilic esophagitis to see how their symptoms and lab results relate to inflammation in their bodies.

Quick facts

Study typeObservational
Ages1 Year to 65 Years
SexAll
Enrollment1500 (estimated)
SponsorUniversity of California, San Diego
Academic / other
Locations1 site (San Diego, California)
StatusRecruiting
StartedFebruary 11, 2019
Main results expectedDecember 17, 2028
Study endsDecember 17, 2028
Registry record updatedJuly 7, 2026
Trial IDNCT03980886 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are children diagnosed with eosinophilic esophagitis who experience symptoms like dysphagia, vomiting, or abdominal pain.

Probably not a fit

Patients without a diagnosis of eosinophilic esophagitis or those not exhibiting relevant symptoms may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on children diagnosed with eosinophilic esophagitis (EoE) at Rady Children's Hospital. Participants will have their medical information, including symptoms, endoscopy results, and lab findings, collected and entered into a database during routine visits. Blood and biopsy samples will be taken for analysis of inflammatory markers and to create a repository for future studies on disease progression and therapeutic responses. The study aims to enhance understanding of EoE's natural history and the relationship between clinical symptoms and molecular changes.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of eosinophilic esophagitis in children.

How similar studies have gone: Other studies have shown success in understanding eosinophilic esophagitis through similar observational approaches, but this specific study adds a novel focus on inflammatory markers.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Have a known EoE diagnosis
* Complain of dysphagia, vomiting, or abdominal pain, especially if recalcitrant to acid blocking therapy (but does not have to be recalcitrant to acid blocking medications)
* Present with food impaction
* Present with esophageal stricture
* Have characteristic endoscopic findings of EoE of pallor, linear furrows, lichenification, white plaques, or concentric rings

Exclusion Criteria:

* None

Where it's running

  • Rady Children's Hospital San Diego
    San Diego, California, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.