Context-aware mobile program to boost social recovery in serious mental illness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial tests mSITE, a blended intervention combining brief in-person psychotherapy, context-triggered smartphone prompts, and remote telephone coaching to target social engagement in people with serious mental illness. Participants are randomized to receive mSITE or a therapist-and-device-matched Supportive Contact (SC) condition. Outcomes focus on changes in the frequency of real-world social interactions measured at baseline and at Weeks 8, 18, and 30, and the study also validates new digital techniques for measuring social behavior. The work is conducted at the University of California San Diego and uses smartphone-based context awareness to deliver just-in-time supports.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Voluntary informed consent to participate and capacity to consent; Age 18 to 65;
* Diagnosis of schizophrenia, schizoaffective, bipolar I disorder or major depression with history of psychosis based on a diagnostic interview and available medical record review;
* Minimum level of social avoidance defined by a score of ≥ 2 on the Scale for the Assessment of Negative Symptoms (SANS) asociality item;
* Be willing and able to speak English at ≥ 6th grade reading level (to read intervention workbook).

Exclusion Criteria:

* Prior cognitive-behavioral therapy in the past 2 years;
* Greater than moderate disorganization on the PANSS (P2- Disorganization item \>5);
* Alcohol or substance dependence in past 3 months based on the diagnostic interview;
* Level of care required interferes with outpatient therapy (e.g., hospitalized; severe medical illness);
* Unable to adequately see or manually manipulate a phone;
* Resident of an integrated housing facility that also provides treatment services.

Where it's running

• University of California - San Diego
  San Diego, California, United States Recruiting

Study contacts

• Principal investigator: Eric Granholm, PhD — University of California, San Diego
• Study coordinator: Jason Holden, PhD
• Email: jlholden@health.ucsd.edu
• Phone: 858-246-2517

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.