Investigating the Mediterranean Diet's Effects on Inflammatory Bowel Disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study explores how dietary changes, specifically adopting a Mediterranean diet, can influence the severity of inflammatory bowel disease (IBD). Researchers will collect blood and stool samples from participants before and after implementing the diet to analyze changes in inflammation markers and gut microbiome composition. By comparing these samples, the study aims to determine the diet's impact on disease state and overall health in individuals with IBD.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years old or older
* Meet classification criteria for inflammatory bowel disease including those with mild to moderate Crohn's Disease as defined by a Crohn's disease activity index between 150-450, with fecal calprotectin\>250, within 1 month of enrollment.

Exclusion Criteria:

* Unable to provide informed consent
* History of or current drug abuse
* Pregnancy
* Start or change in dose of standard-of-care treatment within 12 weeks of the screening
* Known allergy to any component of the proposed diet
* Subjects with significant other medical or psychiatric comorbidities and /or medication use which in
* physician's clinical judgment might difficult the interpretation of the results
* Patients that are not on a stable dose of medications, for instance, steroids, in between samples collection
* Patients on antibiotics
* Patients with C difficile infection within 4 weeks of enrollment

Where it's running

• University of California, San Diego
  San Diego, California, United States Recruiting

Study contacts

• Study coordinator: Monica Guma, M.D., PhD
• Email: mguma@health.ucsd.edu
• Phone: 8588226523

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.