How pesticide spray seasons affect thinking and mood in teens and young adults

Cyclical Alterations In Neurocognitive Performance And Mood Over Two Years In Relation To Pesticide Spray Seasons Among Adolescent And Young Adult Participants Of The Espina Study.

NIH-funded research University of California, San Diego · NIH-11504813

This project follows teens and young adults for two years to look for short-term changes in thinking skills and mood linked to nearby pesticide spray seasons.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11504813 on NIH RePORTER

What this research studies

You would join a group of adolescents and young adults who are seen repeatedly over two years to measure thinking skills and mood around times when pesticides are sprayed nearby. The team combines short-term testing of attention, memory, and mood questionnaires with timing of local spray seasons and exposure measures. They build on earlier follow-ups of the ESPINA participants (about 550 people) and focus on patterns that come and go with the spraying cycles. Visits occur at set times so researchers can compare how you feel and perform before, during, and after spray periods.

Who could benefit from this research

Good fit: Ideal candidates are adolescents and young adults (roughly ages 18–23) who live in or near agricultural areas with seasonal pesticide spraying and can attend repeated study visits.

Not a fit: People who do not live near agricultural pesticide spraying or who are outside the study age range may not receive direct benefit from this work.

Why it matters

Potential benefit: If successful, this work could identify spray-season exposure patterns that harm teen brain function or mood so public health steps can better protect young people.

How similar studies have performed: Previous research has linked organophosphate exposure to cognitive changes, but tracking short-term, cyclical changes in mood and performance around spray seasons is a relatively new approach.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.