NIH-funded research R01 grant

Open data commons for stroke research to speed better treatments

Official title: CRCNS: Open Data Commons for Stroke Research - Promoting FAIR Data Through Community-Driven Design

Funded at University of California, San Diego · NIH-11538878 · Data updated 2026-11-12

A national project to build an open, community-guided data platform so scientists share and reuse preclinical stroke research data to help translate lab findings into effective therapies.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startSeptember 8, 2026
Project endAugust 31, 2031
Funding year2026
Award (this year)$173,786
NIH project number1R01NS153771-01
Project IDNIH-11538878 on NIH RePORTER

Who could benefit from this research

Could help

Patients with stroke or stroke-related conditions could benefit indirectly as new therapies advance from preclinical to clinical testing.

Less likely to help

This grant is focused on data infrastructure; individual patients may not directly participate.

What this research studies

This project creates ODC-Stroke, a cloud-based, federated data platform that makes preclinical stroke data more Findable, Accessible, Interoperable, and Reusable. It will help researchers publish and share datasets with standardized terms, linking data with DOIs and ORCID to improve attribution. International working groups will develop common data elements to harmonize variables across studies and enable large-scale analyses that could accelerate progress toward better therapies for stroke.

Why it matters

Potential benefit: If successful, clinicians and researchers could access richer, harmonized data to identify promising treatment avenues faster and more reliably.

How similar studies have gone: Previous Open Data Commons platforms (OI SCI/TBI) have shown value in data sharing and harmonization, supporting this approach for stroke.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Grethe, Jeffrey S. — University of California, San Diego
  • Study coordinator: Grethe, Jeffrey S.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.