Focal therapy for localized prostate cancer treatment
A Prospective Registry and Longitudinal Study of Patients Undergoing Focal Therapy for Localized Prostate Cancer
This study looks at how well different focal therapy treatments work for men with localized prostate cancer who have chosen this option, by tracking their progress before and after the procedure.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | Male |
| Sponsor | University of California, San Diego Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (La Jolla, California) |
| Trial ID | NCT06270043 on ClinicalTrials.gov |
What this trial studies
This observational study aims to collect and analyze data on the outcomes of prostate cancer patients who have undergone focal therapy. Participants will have already elected or scheduled this treatment method and will be monitored through medical records and questionnaires before and after the procedure. The study seeks to improve patient care by understanding the effectiveness and safety of various focal therapy techniques, including high-intensity frequency ultrasound and cryoablation.
Who should consider this trial
Good fit: Ideal candidates are men with localized prostate cancer who have chosen focal therapy as their treatment option and have a PSA level of 20 or lower.
Not a fit: Patients who are not candidates for focal therapy or those who require alternative treatments like radical prostatectomy or radiation therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance treatment options and outcomes for patients with localized prostate cancer.
How similar studies have performed: Other studies have shown promising results with focal therapy approaches for localized prostate cancer, indicating potential for success in this observational study.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subject has elected or already undergone focal therapy as their standard of care treatment method and declined alternative treatment (active surveillance, radical prostatectomy, and radiation therapy) * PSA ≤ 20 * Ability to complete informed consent form Exclusion Criteria: * Contraindication to follow-up multi parametric MRI or prostate biopsy * Unable to tolerate general or regional anesthesia
Where this trial is running
La Jolla, California
- University of California, San Diego — La Jolla, California, United States (Recruiting)
Study contacts
- Study coordinator: Juan Javier-DesLoges, MD
- Email: jjavierdesloges@health.ucsd.edu
- Phone: 858-657-8786
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.