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Clinical trial Recruiting at 1 site Observational Ages 18 and up Men only

Focal therapy for localized prostate cancer treatment

Official title: A Prospective Registry and Longitudinal Study of Patients Undergoing Focal Therapy for Localized Prostate Cancer

Run by University of California, San Diego · NCT06270043 · Data updated 2026-11-12

This study looks at how well different focal therapy treatments work for men with localized prostate cancer who have chosen this option, by tracking their progress before and after the procedure.

Quick facts

Study typeObservational
Ages18 Years and up
SexMen only
Enrollment500 (estimated)
SponsorUniversity of California, San Diego
Academic / other
Drugs / interventionsradiation
Locations1 site (La Jolla, California)
StatusRecruiting
StartedFebruary 1, 2024
Main results expectedFebruary 1, 2034
Study endsFebruary 1, 2034
Registry record updatedFebruary 26, 2024
Trial IDNCT06270043 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are men with localized prostate cancer who have chosen focal therapy as their treatment option and have a PSA level of 20 or lower.

Probably not a fit

Patients who are not candidates for focal therapy or those who require alternative treatments like radical prostatectomy or radiation therapy may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect and analyze data on the outcomes of prostate cancer patients who have undergone focal therapy. Participants will have already elected or scheduled this treatment method and will be monitored through medical records and questionnaires before and after the procedure. The study seeks to improve patient care by understanding the effectiveness and safety of various focal therapy techniques, including high-intensity frequency ultrasound and cryoablation.

Why it matters

Potential benefit: If successful, this study could enhance treatment options and outcomes for patients with localized prostate cancer.

How similar studies have gone: Other studies have shown promising results with focal therapy approaches for localized prostate cancer, indicating potential for success in this observational study.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Subject has elected or already undergone focal therapy as their standard of care treatment method and declined alternative treatment (active surveillance, radical prostatectomy, and radiation therapy)
* PSA ≤ 20
* Ability to complete informed consent form

Exclusion Criteria:

* Contraindication to follow-up multi parametric MRI or prostate biopsy
* Unable to tolerate general or regional anesthesia

Where it's running

  • University of California, San Diego
    La Jolla, California, United States     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Prostate Cancer 1464University of California, San Diego 1977
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.