Telehealth support for young cancer patients to preserve fertility
Official title: Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients: a Stepped Wedge Cluster Randomized Controlled Trial
Run by University of California, San Diego · NCT05443737 · Data updated 2026-11-12
This study tests a new telehealth program to see if it helps young cancer patients get better support and information about preserving their fertility.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 0 Years to 50 Years |
| Sex | All |
| Enrollment | 2800 (estimated) |
| Sponsor | University of California, San Diego Academic / other |
| Locations | 4 sites (Duarte, California and 3 other locations) |
| Status | Recruiting |
| Started | January 1, 2022 |
| Main results expected | August 31, 2027 |
| Study ends | August 31, 2027 |
| Registry record updated | December 3, 2025 |
| Trial ID | NCT05443737 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include newly diagnosed cancer patients or those experiencing a cancer relapse, aged 0 to 42 years for females and 0 to 50 years for males.
✕Probably not a fit
Patients with non-melanoma skin cancer or metastatic/Stage IV non-thyroid solid tumors may not benefit from this study due to the nature of their treatment and prognosis.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates a multi-component telehealth intervention designed to enhance engagement in oncofertility care among adolescent and young adult cancer patients. The intervention aims to provide tailored support and resources to help these patients make informed decisions regarding fertility preservation. By observing the implementation of this intervention, the study seeks to determine its effectiveness in improving patient outcomes in oncofertility care. The researchers hypothesize that increased engagement will lead to better alignment with patients' fertility goals.
Why it matters
Potential benefit: If successful, this intervention could significantly improve fertility preservation options and outcomes for young cancer survivors.
How similar studies have gone: Other studies have shown promise in using telehealth interventions for similar patient populations, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Newly diagnosed cancer or cancer relapse * Primary language English or Spanish * Receiving oncology care at participating clinical sites * Ages 0 to 42 years if female * Ages 0 to 50 years if male Exclusion Criteria: * Non-melanoma skin cancer, because primary treatment is excision with no infertility risk * Metastatic/Stage IV non-thyroid solid tumors, because of poor prognosis
Where it's running
-
City of Hope
Duarte, California, United States Recruiting -
University of California San Diego
La Jolla, California, United States Recruiting -
Rady Children's Hospital San Diego
San Diego, California, United States Recruiting -
Cancer Resource Center of the Desert
El Centro, California, United States Active not recruiting
Study contacts
- Principal investigator: H. Irene Su, MD, MSCE — University of California, San Diego
- Study coordinator: H. Irene Su, MD, MSCE
- Email: hisu@health.ucsd.edu
- Phone: 858-822-5986
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Follicular Flushing During Abdominal Egg Retrieval in Women with Low Egg Reserve
This study tests whether rinsing the egg sacs during abdominal egg collection yields more eggs and more mature eggs for freezing in women with low ovarian reserve.
-
GnRH agonist versus dual hCG/GnRH trigger for ovulation induction in fertility preservation
We will test whether using a GnRH agonist alone or a dual trigger (GnRH agonist plus hCG) gives better egg retrieval numbers and safety for people with cancer doing egg freezing before gonadotoxic treatment.
-
Combining ovarian tissue freezing with egg (oocyte) freezing versus egg freezing alone
This research will test whether combining ovarian tissue freezing with egg freezing helps adult women with cancer preserve more fertility than egg freezing alone.
-
Long-term follow-up of fertility preservation in women after cancer remission
This project will see how fertility preservation options work long-term for women in remission from cancer or hematological disease, including how often preserved material is used and the psychological effects.
-
When to start hormones after stopping combined birth control for planned egg freezing
This trial tests whether taking a two-month break from combined hormonal birth control versus starting ovarian stimulation immediately affects outcomes for ovary-bearing people aged 18–40 who are planning to freeze their eggs.
-
Fertility-preserving hysteroscopic treatment outcomes for endometrial cancer and atypical hyperplasia
This project tests whether removing lesions by hysteroscopy combined with hormonal therapy helps women with endometrial cancer or atypical hyperplasia preserve fertility and achieve good pregnancy and cancer-control outcomes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.