Web-based support for women living with HIV/AIDS

Women SHINE: Addressing Syndemics and HIV Among Women Through Tech-Based Peer Engagement

NA · University of California, San Diego · NCT05509959

This study is testing a new online support program to see if it can help women living with HIV/AIDS who have faced violence stick to their medication and improve their health.

Quick facts

PhaseNA
Study typeInterventional
Enrollment360 (estimated)
Ages18 Years and up
SexFemale
SponsorUniversity of California, San Diego (other)
Locations1 site (La Jolla, California)
Trial IDNCT05509959 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of Women SHINE, a web-based intervention designed to provide trauma-informed peer navigation and social support for women living with HIV/AIDS who have experienced interpersonal violence. The study will enroll 360 women who are non-adherent to antiretroviral therapy (ART) and will randomly assign them to either the Women SHINE intervention or a control group. Participants in the intervention will receive personalized support through one-on-one sessions, group psychoeducation, and access to online resources over four months. The goal is to improve ART adherence and overall health outcomes for these women.

Who should consider this trial

Good fit: Ideal candidates are cisgender women aged 18 and older, diagnosed with HIV, who have experienced interpersonal violence and are currently prescribed ART but are non-adherent.

Not a fit: Patients who are not cisgender women, have a recent history of ART adherence, or do not have access to an internet browser may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve ART adherence and health outcomes for women living with HIV/AIDS who have faced trauma.

How similar studies have performed: Previous studies have shown that peer navigation and psychoeducation can improve health outcomes for women living with HIV, suggesting that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Cisgender female
* Diagnosis of HIV by a physician, healthcare provider, or community health worker
* Aged 18 years or older
* Speaking and reading English or Spanish
* Adulthood experiences of interpersonal violence
* Currently prescribed ART
* Self-report of \<90% past-month ART adherence
* Not currently participating in another adherence intervention
* Access to an internet browser

Exclusion Criteria:

* Unwillingness to participate in the intervention
* Transgender female
* No diagnosis of HIV by a physician, healthcare provider, or community health worker
* Aged less than 18 years
* Not speaking and reading English or Spanish
* Not currently prescribed ART
* Self-report of \>= 90% past-month ART adherence
* Currently participating in another adherence intervention
* No access to an internet browser
* Cognitive impairment limiting the ability to provide informed consent
* Experiencing only childhood experiences of interpersonal violence
* Inability to safely participate in the study based on secondary screener

Where this trial is running

La Jolla, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: HIV/AIDS, HIV Care Continuum, Psychoeducation

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.