Using advanced chest X-ray technology to screen for lung cancer
Official title: Chest X-ray Tomosynthesis for Detection of Lung Cancer and Lung Disease
Run by University of California, San Diego · NCT06577883 · Data updated 2026-11-12
This study is testing a new type of chest X-ray to see if it can find lung cancer as well as or better than regular CT scans for people being screened for the disease.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 30 Years to 85 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | University of California, San Diego Academic / other |
| Locations | 1 site (San Diego, California) |
| Status | Recruiting |
| Started | November 2, 2023 |
| Main results expected | December 31, 2026 |
| Study ends | June 30, 2027 |
| Registry record updated | August 29, 2024 |
| Trial ID | NCT06577883 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals undergoing lung cancer screening, evaluation of suspicious lung nodules, or those with newly diagnosed lung cancer.
✕Probably not a fit
Patients with a prior history of lung cancer treatment may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational clinical trial aims to evaluate the effectiveness of chest tomosynthesis as a potential alternative to computed tomography (CT) for lung cancer detection. Participants will undergo both chest tomosynthesis and routine CT scans to compare their diagnostic accuracy. The study also focuses on developing artificial intelligence tools to enhance the detection of lung cancer in tomosynthesis images. Researchers will assess the sensitivity and specificity of this new imaging technique in a population undergoing lung cancer screening or evaluation of suspicious lung nodules.
Why it matters
Potential benefit: If successful, this study could provide a less invasive and more accessible method for early lung cancer detection.
How similar studies have gone: Other studies have shown promise in using advanced imaging techniques for lung cancer detection, but this specific approach with chest tomosynthesis is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * undergoing lung cancer screening * undergoing evaluation of suspicious pulmonary nodule * newly diagnosed lung cancer Exclusion Criteria: * prior history of lung cancer treatment
Where it's running
-
University of California San Diego
San Diego, California, United States Recruiting
Study contacts
- Principal investigator: Albert Hsiao, MD PhD — UC San Diego, Department of Radiology
- Study coordinator: Alexander Cypro, MD
- Email: aidaresearch2023@gmail.com
- Phone: 858-2462196
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
ePRO in advanced lung cancer: emotional distress, brain metastasis, and symptom burden
This study tests how patients with advanced lung cancer—some with brain metastases—report emotional distress and symptoms over time using electronic questionnaires.
-
Urine VOC Test to Detect Lung Cancer in Never Smokers
A urine test that looks for volatile compounds is tested to see if it can help detect lung cancer in adults who have never smoked.
-
SI-B036 safety test in advanced and metastatic solid tumors
This early-phase study checks whether SI-B036 is safe and tolerable in adults with advanced or metastatic solid cancers who have had prior therapy.
-
Guaraná Supplement for Cancer-Related Fatigue in People Undergoing Treatment
This study tests whether taking guaraná capsules helps reduce cancer-related fatigue and improve quality of life in adults with breast, lung, colorectal, or gastric cancer who are actively receiving treatment.
-
ENPP1/cGAS and FAP in Solid Tumors in Vietnamese Patients
This Vietnam-based study will test ENPP1, cGAS, and FAP expression in archived tumor samples from Vietnamese adults with solid cancers using immunohistochemistry.
-
Olive oil before lung cancer surgery to see if it lowers chylothorax
This study tests whether drinking 40 mL of extra-virgin olive oil a few hours before lung cancer surgery can reduce chylothorax after tumor removal.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.