Using TRUMATCH Graft Cage for repairing long bone defects

Early Outcomes Utilizing the TRUMATCH Graft Cage for Segmental Long Bone Defects: A Case Series

Observational University of California, San Diego · NCT05668182

This study is testing a new device called the TRUMATCH Graft Cage to see if it helps adults with serious bone injuries in their arms or legs heal better and get back to their normal activities.

Quick facts

Study typeObservational
Enrollment5 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of California, San Diego Academic / other
Locations1 site (San Diego, California)
Trial IDNCT05668182 on ClinicalTrials.gov

What this trial studies

This observational study involves patients aged 18 and older with critical-sized segmental defects in the humerus, femur, or tibia who are treated at UCSD. Participants will receive the TRUMATCH Graft Cage to repair their long bone defects, and data will be collected on healing rates, complications, re-operation rates, time to return to normal activities, and pain levels over a three-year period. The goal is to evaluate the effectiveness of this novel approach in managing challenging long bone injuries.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with segmental defects in the humerus, femur, or tibia requiring surgical intervention.

Not a fit: Patients with severe systemic diseases or those deemed unsuitable for the study by their doctor will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve surgical outcomes and recovery for patients with long bone segmental defects.

How similar studies have performed: While this approach is novel, similar studies evaluating innovative surgical techniques for long bone defects have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Humerus, femur, or tibia segmental defects requiring surgery
* Evaluation and treatment at UCSD
* Ages 18 year and older
* Abiltiy to understand the content of the patient information/informed consent form

Exclusion Criteria:

* Any not medically managed severe systemic disease
* Their doctor has decided that it is in the patient's best interest to receive a different method of repair
* Their doctor has determined that the patient has a condition that would make them unsuitable for participation in the study
* Pregnancy or women planning to conceive within the subject participation period (1 year) note: pregnancy will be self-reported and no test will be performed to test for it
* Prisoner
* Participation in any other pharmacologic or medicinal product study within the previous month that could influence the results of this study.

Where this trial is running

San Diego, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Tibia FractureHumerus FractureFemoral FractureLong Bone Segmental Defect
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.