Comparing lumbar and extraventricular drains to prevent complications after brain hemorrhage

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare the effectiveness of two drainage methods, lumbar drain (LD) and extraventricular drain (EVD), in preventing vasospasm in patients who have experienced subarachnoid hemorrhage. Patients admitted to UCSD Hillcrest or Thornton Hospital will be randomly assigned to receive either LD or EVD as part of their treatment. The study will observe outcomes such as the incidence of clinical vasospasm, the amount of subarachnoid blood, length of ICU stay, and the need for permanent ventriculoperitoneal shunt. This prospective randomized controlled trial seeks to establish clearer guidelines for the optimal drainage method in these patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* patients received at the UCSD Medical Center with grade II, III, IV subarachnoid hemorrhage or patients with aneurysmal SAH with radiographic evidence.

Exclusion Criteria:

* patients under the age of 18, excluding minors from this study

Where it's running

• UCSD Medical Center
  San Diego, California, United States Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Smartphone-based EEG to detect hidden awareness in ICU patients with brain injuries

  Researchers will test a smartphone-enabled EEG to see if it can reveal Cognitive Motor Dissociation in ICU patients who can’t show commands at bedside.

  Recruiting Columbia University · Miami, Florida and 8 other locations · NCT07917728

• French validation of the SAHOT outcome tool after subarachnoid hemorrhage

  This study tests whether a French version of the SAHOT questionnaire reliably measures outcomes in adults after subarachnoid hemorrhage.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris · NCT07894666

• Prognostic model for neurocritical patients using multimodal brain monitoring

  This study tests a model that uses EEG, TCD, and NIRS data to predict 90-day outcomes (awake, coma, or death) in adults with acute brain injuries in intensive care.

  Recruiting Xiangya Hospital of Central South University · Changsha, Hunan · NCT07115459

• Investigating the effects of stellate ganglion block on retinal blood flow

  This study is testing if a special nerve block used for pain relief can improve blood flow in the eyes of patients with severe brain injuries.

  Recruiting University of Texas Southwestern Medical Center · Dallas, Texas · NCT06797752

• Evaluating outcomes in neurosurgery using standardized measures

  This study is trying to see how different factors affect the results of brain surgeries by collecting information from patients before and after their operations.

  Recruiting at 11 sites Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Bergamo, BG and 26 other locations · NCT06724029

• Assessing ventilatory parameters in patients with acute neurological injuries

  This study is trying to see how different breathing machine settings affect the brain health of adults with serious neurological injuries like strokes or brain trauma.

  Recruiting Ramos Mejía Hospital · Ciudad Autonoma de Buenos Aires, Buenos Aires · NCT06192342

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.