Clinical trial Recruiting at 1 site Interventional Ages 18 to 45

Effects of Hypoxic Breathwork

Official title: Impacts of Rhythmic and Hypoxic Breathwork on EEG, Mood, Sleep, and Physiology

Run by University of California, San Diego · NCT06317259 · Data updated 2026-11-12

This study is testing how a week of breathing exercises combined with music and positive messages can affect people's health, stress, and sleep.

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexAll
Enrollment75 (estimated)
SponsorUniversity of California, San Diego
Academic / other
Locations1 site (La Jolla, California)
StatusRecruiting
StartedJune 17, 2024
Main results expectedOctober 2027
Study endsJanuary 2028
Registry record updatedAugust 4, 2026
Trial IDNCT06317259 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy adults aged 18-45 who can commit to the breathwork regimen.

Probably not a fit

Patients with a history of regular breathwork practice or those on psychoactive medications may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project investigates the physiological and biochemical changes that occur during a week-long practice of hypoxic breathwork combined with music and affirmative messaging. Participants will engage in daily sessions of slow-paced breathing and breath-holding, with high-density EEG recordings taken at the beginning and end of the week to assess brain activity. Additionally, various biological samples and questionnaires will be collected to evaluate the impact of breathwork on overall health, stress levels, and sleep quality. The study aims to explore how breathwork can influence bodily functions and mental well-being.

Why it matters

Potential benefit: If successful, this approach could enhance stress management and improve sleep quality for participants.

How similar studies have gone: While breathwork has been explored in various contexts, this specific combination of hypoxic techniques and EEG analysis is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Persons, aged 18-45
* Availability for the duration of the study
* In good general health as revealed by self-report
* Stated willingness and capability to adhere to the breathwork regimen
* Agreement to adhere to Lifestyle Considerations (see section 5.3) throughout study duration
* Provision of signed and dated informed consent form

Exclusion Criteria:

1. Current or past regular breathwork practice
2. Current use of psychoactive medications (e.g., anti-depressants or anxiolytics)
3. Pregnancy
4. Bedtime past 11:30pm or regularly getting less than 6 hours of sleep per night.
5. Feverish illness within 10 days
6. Regular smoker or tobacco user ( \> 1 cigarette, gum or pouch per month)
7. Presence of blood pressure above 140 systolic and/or 90 diastolic, seizure disorder, asthma, or serious cardiac fibrillation disorders.

Where it's running

  • UC San Diego
    La Jolla, California, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.