Using Coenzyme Q10 to help veterans with Gulf War illness
Coenzyme Q10 for Gulf War Illness: A Replication Study
This study is testing if a special form of coenzyme Q10 can help veterans with Gulf War illness feel better and improve their quality of life.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 192 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | University of California, San Diego Academic / other |
| Locations | 1 site (La Jolla, California) |
| Trial ID | NCT06515184 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of a high-quality preparation of coenzyme Q10 (ubiquinone) in improving symptoms, functionality, and quality of life for veterans suffering from Gulf War illness. Participants will receive either the active supplement or a placebo in a randomized manner. The study will include veterans who meet specific deployment and symptom criteria and will involve remote participation for assessments. Blood draws will be conducted at local facilities to monitor health outcomes throughout the study.
Who should consider this trial
Good fit: Ideal candidates are veterans who meet CDC and Kansas criteria for Gulf War illness and have rated their health prior to deployment as 'very good' or 'excellent'.
Not a fit: Patients currently participating in another clinical trial or those with ongoing adverse effects from previous medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a new treatment option to alleviate symptoms and improve the quality of life for veterans with Gulf War illness.
How similar studies have performed: Previous studies have indicated potential benefits of coenzyme Q10 in various conditions, but this specific application for Gulf War illness is being explored in this replication study.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Meets both CDC and Kansas deployment and symptom inclusion criteria. * Does not have a disqualifying condition. * Able to travel to a local Quest facility for study blood draws. * Adequate internet access to allow ZoomPro visit participation and remote survey completion. * Health prior to the Gulf War rated as "very good" or "excellent" (to exclude persons who may have had other health conditions with different mechanisms as the cause of their symptoms). * Willing to defer initiation of discretionary treatments or supplements during the expected course of study participation. Exclusion Criteria: * Participating in another clinical trial. * Still-evolving adverse effects following another medication or health condition, such as covid or fluoroquinolone use. * On Coumadin/ warfarin. * Unable to participate for the required duration of the study.
Where this trial is running
La Jolla, California
- UC San Diego — La Jolla, California, United States (Recruiting)
Study contacts
- Principal investigator: Beatrice A Golomb, MD, PhD — University of California, San Diego
- Study coordinator: Janis B Ritchie, BSN
- Email: jbritchie@ucsd.edu
- Phone: 858-558-4950
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.