Using Coenzyme Q10 to help veterans with Gulf War illness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of a high-quality preparation of coenzyme Q10 (ubiquinone) in improving symptoms, functionality, and quality of life for veterans suffering from Gulf War illness. Participants will receive either the active supplement or a placebo in a randomized manner. The study will include veterans who meet specific deployment and symptom criteria and will involve remote participation for assessments. Blood draws will be conducted at local facilities to monitor health outcomes throughout the study.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Meets both CDC and Kansas deployment and symptom inclusion criteria.
* Does not have a disqualifying condition.
* Able to travel to a local Quest facility for study blood draws.
* Adequate internet access to allow ZoomPro visit participation and remote survey completion.
* Health prior to the Gulf War rated as "very good" or "excellent" (to exclude persons who may have had other health conditions with different mechanisms as the cause of their symptoms).
* Willing to defer initiation of discretionary treatments or supplements during the expected course of study participation.

Exclusion Criteria:

* Participating in another clinical trial.
* Still-evolving adverse effects following another medication or health condition, such as covid or fluoroquinolone use.
* On Coumadin/ warfarin.
* Unable to participate for the required duration of the study.

Where it's running

• UC San Diego
  La Jolla, California, United States Recruiting

Study contacts

• Principal investigator: Beatrice A Golomb, MD, PhD — University of California, San Diego
• Study coordinator: Janis B Ritchie, BSN
• Email: jbritchie@ucsd.edu
• Phone: 858-558-4950

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Acupuncture for relieving symptoms of Gulf War Illness

  This trial will test whether regular acupuncture can help veterans with Gulf War Illness feel less fatigued, have less pain, and improve physical functioning.

  Recruiting at 3 sites University of Utah · Berkeley, California and 9 other locations · NCT06716411

• Cranial electrical stimulation with brain imaging for Gulf War illness headaches and pain

  This project will try a portable cranial electrical stimulation device (Alpha-Stim) to see if it reduces headaches and body pain in Gulf War veterans with Gulf War Illness.

  Recruiting Emory University · Atlanta, Georgia · NCT07151248

• Montelukast for cognitive and mood symptoms in Gulf War veterans

  This trial tests whether montelukast, an FDA-approved asthma medicine, can improve thinking, mood, and daily function in veterans with Gulf War Illness.

  Recruiting Phase 1 Baylor College of Medicine · Houston, Texas · NCT05992311

• Identifying blood biomarkers for Gulf War Illness

  This study is trying to find specific blood markers in veterans with Gulf War Illness to see how they relate to memory problems and other brain issues.

  Recruiting at 3 sites Roskamp Institute Inc. · Palo Alto, California and 2 other locations · NCT05736146

• Growth hormone therapy for veterans with Gulf War Illness and hormone deficiency

  This study is testing if growth hormone therapy can help veterans with Gulf War Illness and hormone deficiency feel better by reducing symptoms like fatigue and pain.

  Recruiting at 2 sites Phase 2 Baylor College of Medicine · Houston, Texas and 1 other locations · NCT05355272

• Testing N-Acetyl Cysteine for Gulf War Veterans with Chronic Symptoms

  This study is testing if N-Acetyl Cysteine can help Gulf War veterans with chronic symptoms like fatigue and pain by improving their body's ability to fight stress and boost energy levels.

  Recruiting at 4 sites Early Phase 1 Nova Southeastern University · Palo Alto, California and 6 other locations · NCT04987775

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.