Comparing two laser systems for breaking up kidney stones

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research evaluates the effectiveness of two laser systems, the Thulium Fiber Laser (TFL) and the Thulio Pulsed Thulium:YAG (p-Tm:YAG), in treating kidney stones through ureteroscopy. The study aims to determine if the p-Tm:YAG laser is as effective as TFL in terms of dusting ablation efficiency and speed. Participants will undergo a minimally invasive procedure where the lasers will be used to break up kidney stones, with outcomes measured in a controlled environment. This is the first large-scale study directly comparing these two laser technologies for kidney stone treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Solitary renal stone 7 to 20 mm in size or in the case of multiple stones the conglomerate diameter (additive maximal diameter of all stones on axial imaging of computed tomography) of 7-20 mm is required
* Must be a suitable operative candidate for flexible ureteroscopy per American Urological Association guidelines
* Must be able to give consent
* Bilateral ureteroscopy will be permitted but only the first side (per surgeon discretion) will be included in the study
* Surgeons participating in the study must be urological attending surgeons or fellows with subspecialty training in Endourology

Exclusion Criteria:

* Concomitant stones in the ureter
* Prior ipsilateral upper urinary tract reconstructive procedures or history of ipsilateral ureteral stricture
* Prior radiotherapy to the abdomen or pelvis
* Neurogenic bladder or spinal cord injury
* Pregnancy
* Untreated UTI

Where it's running

• University of California, San Diego
  San Diego, California, United States Recruiting

Study contacts

• Study coordinator: Jade McDermott, BS
• Email: j3mcdermott@health.ucsd.edu
• Phone: 858-777-9721

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.