How radiation affects cervical cancer biology and treatment side effects

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects blood and tumor or vaginal biopsies from women with cervical cancer who are scheduled to receive brachytherapy as part of their standard chemo‑radiation care. Samples are taken before treatment, during therapy, and on the last day of radiation to measure tissue factor and other molecular changes over time. The investigators will use these specimens for translational laboratory analyses to identify pathways altered by radiation. Findings could point to molecular targets for future targeted radiotherapy or immunotherapy approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* Pathological diagnosis of cervical cancer
* Scheduled to receive brachytherapy for cervical cancer

Exclusion Criteria:

* Pregnancy or lactation
* Inability to provide a tissue sample

Where it's running

• University of California San Diego
  La Jolla, California, United States Recruiting

Study contacts

• Principal investigator: Jyoti Mayadev, MD — University of California, San Diego
• Study coordinator: Jyoti Mayadev, MD
• Email: CancerCTO@health.ucsd.edu
• Phone: 858-822-5354

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.