Condition
Blood Pressure clinical trials and research
As of November 12, 2026, Find a Trial lists 78 Blood Pressure clinical trials that are recruiting, at sites in 23 countries (most in United States (41), China (8), United Kingdom (4)). By phase: Early Phase 1 (3), Phase 4 (2), Phase 1/2 (2), Phase 3 (1). The most active sponsors are Columbia University (4), GE Healthcare (4), Guangdong Provincial People's Hospital (3). There are also 246 NIH-funded research projects on Blood Pressure, with $131.6 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 78Clinical trials
- 246NIH research projects
- 23Countries
Newest Blood Pressure clinical trials
All recruiting trials (78)
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Overnight Temperature Regulation to Test Gut Health, Inflammation, and Circadian Rhythms
This study tests whether two weeks of using the Eight Sleep Pod at night can improve gut bacteria balance, lower inflammation, and strengthen daily temperature and blood pressure rhythms in postmenopausal women and age-matched men with poor sleep.
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Automated Non-Invasive Blood Pressure: Tracking Blood Pressure Changes Using SpO2 Data
This study tests an algorithm that estimates blood pressure changes using data from an SpO2 sensor in patients in the OR, PACU, or ICU who already have invasive BP measured as part of standard care.
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AI-guided prediction of blood pressure changes in spinal cord injury using perfusion index during a cool-temperature test
This study tests whether perfusion index can reliably predict changes in systolic blood pressure in people with spinal cord injury during a controlled cool temperature challenge.
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NIBP Accuracy Validation in Adults
This study tests how accurately a non-invasive blood pressure device measures blood pressure in adults by comparing it with arterial line readings.
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Micronutrient Enhancement for Development and Health in Adolescent Girls
This study tests whether daily micronutrient supplements (MMS or MMS+), compared with weekly iron-folic acid, can improve school performance and growth in 10- to 18-year-old girls in rural Bangladesh.
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New Non-Invasive Blood Pressure (NIBP) Enhancement for Neonates and Children
This study tests a new NIBP device enhancement in neonates and kids to see if it can measure blood pressure more accurately.
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NeoMayor: a smartphone-guided lifestyle program to improve heart health in older adults in Chile
A smartphone app helps older adults at cardiovascular risk in Chile try better physical activity, diet, sleep, and well-being to see if their heart health improves.
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Non-invasive blood pressure accuracy study for adults
This study tests whether non-invasive blood pressure readings match invasive aortic pressure measurements in adults who need arterial line monitoring.
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Dyadic Multidimensional Sleep Health Promotion for Couples
A couples-focused program tests whether a multidimensional sleep health approach can improve sleep quality and blood pressure in both partners.
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Breathing retraining for pregnant women with POTS
This trial will test whether diaphragmatic breathing exercises help pregnant women with POTS reduce dizziness, rapid heart rate, and other orthostatic symptoms.
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How shorter sleep changes blood pressure responses
We will test whether shorter nightly sleep changes blood pressure responses in healthy 18–45-year-olds who are either normal weight or have obesity.
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Home-based inspiratory muscle training to lower dementia risk in older adults
This study will test whether an 8-week, daily home inspiratory breathing program can lower blood pressure and improve thinking, mood, and sleep in adults aged 60–80 who have risk factors for dementia.
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Think Tank nutritional drink to help thinking after stress in middle-aged women.
This trial will test whether taking the 'Think Tank' nutritional drink helps thinking and mood after a physical and psychological stressor in healthy women aged 40–60 who drink caffeine daily.
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Potato-rich diet for cardiometabolic health in adults with type 2 diabetes risk
This study tests whether a potato-rich healthy eating pattern can improve cardiometabolic health in adults aged 50–70 who are at risk for type 2 diabetes but not yet diagnosed.
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Produce-prescription program to support healthy eating for families in rural North Carolina
This program will try giving families in specified rural North Carolina counties regular boxes of fresh produce plus nutrition education to see if parents and their 8–14-year-old children eat more fruits and vegetables and improve health measures.
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Continuous finger-cuff versus intermittent arm-cuff blood pressure monitoring during outpatient surgery
This test tries continuous VitaWave finger‑cuff blood pressure monitoring against standard arm cuff readings in adults having elective noncardiac outpatient surgery.
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Equol and vascular function in women with CKD
This study tests whether taking equol for 12 weeks improves vascular function in postmenopausal women with chronic kidney disease.
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Remote ischaemic conditioning to improve brain blood-flow regulation in older adults
This project will test whether different doses of remote ischaemic conditioning (brief blood-pressure-cuff interruptions of limb blood flow) can improve dynamic cerebral autoregulation in people aged 65–85.
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Diet, zinc, inflammation, and body composition in multi-ethnic reproductive-age women in Jakarta
This project will see if usual dietary patterns and hair zinc levels are linked to body composition, inflammation (TNF-α), and blood pressure in women aged 19–49 who live in Jakarta.
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How COVID-19 affected fitness, sleep, diet, and blood pressure
This project will see if past COVID-19 or long COVID is linked to changes in fitness, physical activity, blood pressure, sleep, and mental stress in adults aged 18 to 75.
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Stenting blocked aorto-iliac arteries to lower blood pressure
This pilot will try stenting chronic aorto-iliac occlusions in adults to see if opening these blockages lowers central blood pressure and related heart stress markers.
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Enjoying affordable, tasty meals together
This pilot will test whether providing meal kits plus tailored nutrition education helps lower-income adults aged 40 and older with obesity and cardiometabolic risk improve food security, diet quality, stress, quality of life, and heart-related risk factors compared with general nutrition materials.
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Remote app monitoring for people with chronic heart failure
It will test whether using a smartphone telemonitoring app for people with chronic heart failure to report blood pressure and body weight helps support care and detect problems earlier.
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Effects of income instability on mental and physical health
This study is testing how changes in income affect the mental and physical health of women in northern Ghana who live in smaller households.
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Cocooned Moms: App-based maternal mental health and care coordination for pregnant Black women
This project will test whether free access to the culturally tailored InovCares mobile app can lower stress, depressive symptoms, improve sleep, and reduce blood pressure in pregnant Black women.
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Daily intake of short-chain fatty acids and its effects on metabolic health
This study is testing whether drinking a daily beverage with short-chain fatty acids can help people at risk for metabolic syndrome improve their heart and metabolic health over 12 weeks.
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Lentil protein hydrolysate for blood pressure control, vascular health, and exercise performance
This will test whether a daily lentil protein supplement helps control blood pressure and improve blood vessel function and exercise performance in healthy adults.
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Exploring the health benefits of sauna bathing
This study tests if using a sauna followed by cold water immersion can help people aged 18 to 70 manage their blood pressure and improve heart health.
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Using ketone supplements to manage salt intake effects in older adults
This study is testing if ketone supplements can help older adults manage the harmful effects of a high-salt diet on their heart health and blood pressure.
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Mapping blood pressure and brain blood flow during anesthesia
This study tests how blood pressure affects blood flow to the brain during anesthesia to help keep patients safe during surgery.
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Resistance training load and blood pressure in postmenopausal women
This trial will test whether low-load (50% 1‑RM) or high-load (80% 1‑RM) resistance exercise, performed with the same high effort, better lowers post-exercise and ambulatory blood pressure in postmenopausal women aged 50–70.
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Diabetes Complications in People with Cystic Fibrosis-Related Diabetes (SPeCTRuM)
This project will see how common diabetes-related complications (like eye, nerve, and blood vessel problems) are in adolescents and adults living with cystic fibrosis-related diabetes.
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Stress-management program to reduce heart disease risk in women with HIV
This program will test whether the SMART stress-management intervention can lower blood pressure and other heart-disease risks for women living with HIV in the Southern US.
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Exploring the link between blood pressure and cognitive decline after stroke
This study looks at how blood pressure levels might affect thinking and memory problems in people who have had a stroke.
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ViTrack continuous non-invasive wrist blood pressure monitoring for surgical patients
This test sees if the ViTrack wrist device can continuously track blood pressure in adults having noncardiac surgery who need an arterial line.
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Dexmedetomidine's effects on blood pressure during intubation in hypertensive patients
This study tests if giving dexmedetomidine can help lower blood pressure and anxiety in older patients with high blood pressure during intubation for surgery.
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Use smartphone fingertip video to screen and monitor high blood pressure
This project will test whether a smartphone fingertip video method can reliably screen and track high blood pressure in adults who are either presumed healthy or referred for suspected hypertension.
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Sleep2BWell: adding sleep health to diet and activity for better blood pressure
This program will try adding a sleep-health module to a community diet-and-exercise program to see if it helps adults with elevated blood pressure in underserved New York City neighborhoods.
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Effects of Lipids on Health in Night Shift Workers
This study is testing how certain fats in the body affect heart health and blood sugar in people who work night shifts, while also trying a new eating schedule to see if it helps.
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Effects of California grapes on gut and heart health in overweight adults
This study is testing whether eating freeze-dried grape powder can improve gut and heart health in overweight adults aged 45-70.
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Validating the CART BP ring cuffless blood pressure monitor
This study will test whether the CART BP ring gives blood pressure readings that match the standard cuff method in adults with suspected high or low blood pressure.
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Assessing personalized blood pressure targets using advanced monitoring
This study is testing a new way to set personalized blood pressure goals for high-risk patients during heart surgery to see if it can improve their recovery.
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A multidimensional sleep health program to improve blood pressure and cardiometabolic risk
This program tests whether a multi-part sleep health intervention can lower blood pressure and improve blood sugar, body measures, and lifestyle in adults aged 30–65 with elevated systolic blood pressure and poor sleep.
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Focused ultrasound treatment for high blood pressure
This study is testing a new ultrasound treatment that aims to lower blood pressure by targeting fat around the kidneys in people with high blood pressure.
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Effects of Cognitive Behavioral Therapy and Trazodone on Sleep and Blood Pressure in Insomnia
This study is testing whether Cognitive Behavioral Therapy and trazodone can improve sleep quality and blood pressure in people with insomnia who either sleep less or have normal sleep duration.
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Improving blood pressure control through community partnerships and remote monitoring
This study is testing if adding support from community health workers to a remote blood pressure management program can help people control their blood pressure better than just using the program alone.
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Study on hydration and potassium effects on blood pressure in young Black adults
This study tests how drinking enough water and taking potassium can affect blood pressure in young Black adults aged 18-30.
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Examining blood pressure treatment in ICU patients with brain hemorrhage
This study tests how changing blood pressure affects blood flow in the brains of ICU patients who have had a brain hemorrhage.
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TelTex4BP: A mobile program to help adults with hypertension in Nepal
A mobile text and phone-based program (TelTex4BP) helps adults with high blood pressure in Nepal take their medicines and adopt healthier habits to lower blood pressure.
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Reducing air pollution exposure to lower blood pressure in NYC public housing residents
This study is testing if using portable air cleaners can help lower blood pressure for adults with high blood pressure living in public housing in New York City by reducing air pollution indoors.
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Evaluating a new method for continuous blood pressure monitoring during surgery
This study tests a new device for continuously monitoring blood pressure during surgery to see if it works better and is safer than the traditional method.
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Transcutaneous spinal stimulation to improve blood pressure after a recent spinal cord injury
We will try a noninvasive spinal stimulation to see if it raises and steadies blood pressure in people 7–30 days after a thoracic spinal cord injury who have low blood pressure or dizziness when sitting up.
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Transcutaneous spinal stimulation to stabilize blood pressure after spinal cord injury
This will test whether noninvasive transcutaneous spinal cord stimulation can raise and stabilize blood pressure in people with chronic high-level spinal cord injuries who experience orthostatic hypotension.
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Epidural spinal cord stimulation for managing blood pressure and low back pain
This study is testing if epidural spinal cord stimulation can help people with chronic low back pain and high blood pressure feel better by lowering their blood pressure and relieving their pain.
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Reducing blood pressure in mid-life adults who binge drink
This study is testing whether an 8-week exercise program can help mid-life adults who binge drink lower their blood pressure and improve their overall health.
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Breaking up long periods of sitting to improve heart and metabolic health
This study is testing how often and how long people should take breaks from sitting to see if it can help improve their heart and metabolic health.
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Using Transcutaneous Spinal Cord Stimulation to stabilize blood pressure after spinal cord injury
This study is testing whether a new method using Transcutaneous Spinal Cord Stimulation can help stabilize blood pressure in people with recent spinal cord injuries during their rehab.
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Reducing blood pressure to prevent cognitive decline in older adults
This study is testing if better blood pressure management can help older adults with high blood pressure avoid memory problems and dementia.
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Comparing morning and bedtime dosing of blood pressure medication
This study is testing whether taking blood pressure medication in the morning or at bedtime works better to lower blood pressure in people with high blood pressure who haven't been treated before.
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Contactless measurement of vital signs using a camera-based system
This study is testing a new camera system that measures vital signs like blood pressure and heart rate without touching the patient to see if it works well for everyone and helps reduce infection risk.
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Inspiratory muscle training to lower blood pressure in postmenopausal women
This study is testing if a special breathing exercise can lower blood pressure more effectively than regular walking in postmenopausal women with high blood pressure.
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Reducing inflammation in obese patients with hypertension
This study is testing if a medication called clonidine can lower inflammation in obese people with high blood pressure compared to a control group.
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High-resistance inspiratory muscle training for managing blood pressure in chronic kidney disease
This study is testing if a special breathing exercise can help lower blood pressure in older adults with chronic kidney disease who struggle to control their hypertension.
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Managing blood pressure during major surgery
This study tests whether a tighter blood pressure management method during major surgery can help patients keep their blood pressure stable compared to regular management.
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Understanding how glucose and fat affect blood vessel health
This study is testing how sugar and fat in the body affect blood vessel health and blood pressure in healthy adults.
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Examining blood pressure patterns in people at risk for heart disease
This study looks at daily blood pressure patterns in people at risk for heart disease, especially those with kidney issues, to see how these patterns might help identify who could benefit from specific treatments.
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Impact of early menopause on blood pressure regulation in women
This study is trying to see how early menopause affects blood pressure control in women aged 35 to 70 by comparing those who went through menopause early with those who haven’t.
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Investigating the link between blood pressure levels and hospital complications
This study looks at how blood pressure levels in hospitalized patients might be linked to complications and deaths while they are in the hospital.
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Monitoring blood pressure at home for elderly patients
This study looks at how checking blood pressure at home can help older adults in China manage their health and avoid serious heart problems.
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Comparing non-invasive blood pressure monitoring with invasive methods after cardiac surgery
This study is testing a new non-invasive blood pressure monitor to see if it gives accurate readings compared to traditional invasive methods right after heart surgery.
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Observational study of a new wrist blood pressure monitor
This study is testing a new wrist blood pressure monitor to see if it works as well as traditional upper arm monitors for people managing high blood pressure.
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Research on health inequality and genetic disparity in cardiovascular diseases
This study is trying to understand how health differences and genetics affect heart diseases in people from various ethnic backgrounds in the UK to help improve treatments for everyone.
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Registry on controlling blood pressure in ten thousand patients
This study is testing how well 24-hour blood pressure monitoring can help people with high blood pressure manage their condition and improve their heart health.
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Examining how COX blockade affects blood pressure and vein size
This study is testing if a pain medication affects blood pressure and vein size in people during a specific blood flow test.
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Investigating how leg vein distension affects blood pressure
This study is testing how swelling in the leg veins affects blood pressure, especially when standing up, to help understand how the body keeps blood pressure steady during changes in position.
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Using lung recruitment maneuvers to predict fluid needs in children under anesthesia
This study is testing if special breathing techniques can help doctors figure out if kids under anesthesia need extra fluids during surgery.
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Lowering Blood Pressure in Adults With Type 2 Diabetes
This study is testing if lowering blood pressure to below 120 mm Hg with a combination of medications can help adults with type 2 diabetes avoid serious heart and brain problems.
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How changes in brain blood flow affect breathing during sleep
This project will test whether temporarily lowering blood flow to the brain changes how healthy adults' breathing responds to low oxygen and high carbon dioxide during normal sleep and short periods of low oxygen.
NIH-funded research (newest 40 of 246)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Actions to Decrease Disparities in Blood Pressure Control for Blacks
Aiming to help Black patients manage high blood pressure by using nurses, community health workers, and home monitoring in real-world clinics.
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Cognitive behavioral therapy and trazodone for insomnia phenotypes with high blood pressure
A clinical study tests how CBT-I and the sleep drug trazodone work for adults with insomnia and high blood pressure, focusing on a specific sleep duration pattern.
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Music-powered tools to boost blood pressure and stroke prevention for Nigerian youth and their older caregivers
This project uses popular music to help Nigerian youths and their older family members start and stick to blood pressure and stroke prevention habits.
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Non-invasive, continuous blood pressure monitoring for prenatal maternal health
A wearable device from PyrAmes uses comfortable, non-invasive sensors and smart software to constantly monitor a pregnant person’s blood pressure and heart health so doctors can protect both mom and baby.
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Smartphone app helps pregnant women in Ghana monitor blood pressure at home
A smartphone app is being customized for pregnant women in Ghana to support home blood pressure monitoring and improve safety during pregnancy.
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Nap duration during night shifts and blood pressure health
A Phase II study will test how long night shift naps should be to restore normal blood pressure patterns and maintain safe performance, while considering caffeine use, for night workers.
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Remote blood pressure monitoring with pharmacist-led telehealth for people living with HIV
A plan to remotely track blood pressure and support HIV patients with pharmacist-led telehealth and reminders to bring BP under control.
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How eating times affect blood pressure in obesity
This project asks how when you eat affects blood pressure in obesity, aiming to find simple timing strategies to help people manage blood pressure.
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PFAS in drinking water and blood pressure in adults and kids
This project looks at how chemical PFAS in drinking water may be linked to high blood pressure in both adults and children.
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Smart wrist wearable for continuous cuffless blood pressure and vital signs across diverse skin tones
A wearable wrist device will continuously monitor blood pressure, heart rate, and breathing in adults of diverse skin tones and body types, using non-invasive sensors and smart algorithms.
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ASPIRE: Making self-measured blood pressure work for primary care patients
A practical plan to help adults manage high blood pressure by using home blood pressure readings in regular clinic care.
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Resistance Exercise Training for Blood Pressure and Blood Vessel Health in Middle-Aged Women
A large study will test whether 16 weeks of supervised resistance exercise can lower blood pressure and improve blood vessel health in women aged 40–64 with high blood pressure.
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Non-Invasive AI-Enhanced Neonatal Blood Pressure Monitoring in NICUs
A new AI-powered system uses the baby’s existing sensors to continuously track blood pressure in the NICU without invasive procedures, helping clinicians spot problems early.
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Renal telocytes and Piezo1: how kidney sensors control blood pressure
Researchers will study a kidney cell type and a pressure sensor protein to understand how the body keeps blood pressure in check.
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Molecular clues to daily blood pressure changes and heart disease
Researchers are exploring how dynamic blood pressure changes throughout daily life relate to heart disease, with new protein measurements to identify potential targets for better control.
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Remote blood pressure monitoring with pharmacist-led telehealth after ED discharge
A new program helps adults with high blood pressure receive BP monitoring and medication support after leaving the emergency department, with pharmacists guiding telehealth visits and automated reminders.
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Environmental factors driving disparities in hypertensive pregnancy disorders and blood pressure over time
This project studies how everyday environmental factors like air pollution and temperature affect blood pressure changes and HDP disparities in pregnant people.
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Music-powered tools to expand blood pressure and stroke prevention for youth and older caregivers
A study in Nigeria will use popular music and community projects to help young people and their older family members adopt proven blood pressure and stroke prevention practices.
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Barber and Pharmacist Team Up to Lower Blood Pressure
A community-based program where barbershops partner with pharmacists to help Black men lower their blood pressure in Los Angeles.
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Insomnia subtypes and sleep meds: CBT-I and trazodone for adults with high blood pressure
We’re testing whether a sleep therapy (CBT-I) and the antidepressant trazodone help adults with insomnia and high blood pressure, especially those with the short-sleep-insomnia subtype.
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Music-based programs to lower blood pressure and prevent stroke
Using locally created music campaigns to help Nigerian youth and their older caregivers lower blood pressure and reduce stroke risk.
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Cognitive-Behavioral Therapy and Trazodone for Sleep and Blood Pressure in Insomnia Subtypes
This program tests how CBT-I and trazodone help sleep and blood pressure in adults with insomnia, focusing on those with short sleep duration versus normal sleep duration.
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Sleep therapy versus trazodone for short-sleep insomnia and high blood pressure
This project compares a talk-based sleep program (CBT-I) and the medication trazodone to help adults with insomnia who also have elevated blood pressure, especially those who sleep less at night.
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Daily diary study on how anticipated and vicarious stress affect blood pressure
A daily diary study with adults to understand how expecting stressful events and hearing about others’ stress influence blood pressure at home.
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Actions to Decrease Disparities in Blood Pressure Control for Blacks
A program to help Black patients better control high blood pressure by using nurse support, home monitoring, and community health workers integrated into everyday primary care.
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ENaC channels and salt-sensitive blood pressure in immune cells
This grant studies how a salt-sensing channel called ENaC in immune cells like dendritic cells and monocytes may influence blood pressure in people who are salt-sensitive.
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Enhanced Diagnosis and Management of Preeclampsia with a High-Accuracy Wearable Blood Pressure Monitor
A new wearable blood pressure monitor called neoBP™ aims to give very accurate, real-time BP data to help manage preeclampsia in pregnant people.
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AirClean NYC: Reducing indoor air pollution to lower blood pressure in public housing residents
This study tests whether using personal air cleaners at home can lower blood pressure among adults living in New York City public housing who have hypertension or are being treated for it.
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What makes high-fat diets raise blood pressure differently in women and men
A research project explores why eating lots of saturated fat may raise blood pressure more in women than men by studying immune cell changes and fat tissue.
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Cuffless blood pressure monitoring using fast wearable optical sensing
A new wearable device using high-speed optical sensing aims to measure blood pressure without a cuff, making BP tracking easier and more comfortable for adults.
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Antihypertensive self-titration to improve blood pressure control
A patient-friendly plan to allow adults with high blood pressure to safely adjust their blood pressure medications at home using a provided algorithm.
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How daily worries and others' stress affect blood pressure
This project will measure whether everyday worries and hearing about stressful events that happen to others raise home blood pressure in adults.
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Electronic health record tools to optimize blood pressure for pregnancy-capable adults in primary care
A technology-based plan helps women with high blood pressure who could become pregnant manage their BP safely in primary care.
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Chrono-exercise for better blood pressure and blood vessel health
Aging adults with high blood pressure may be able to improve their nighttime blood pressure and vascular health by scheduling exercise at specific times.
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DASH grocery deliveries to lower blood pressure for Black adults in urban food deserts
This project provides DASH-style groceries to Black adults living in urban food deserts to help lower their blood pressure.
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Salt and immune system link to high blood pressure and lupus
A patient-friendly study examines how salt affects immune cells to contribute to high blood pressure and lupus, with potential ways to reduce damage.
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How swings in blood pressure affect brain blood vessels and support cells
This project aims to learn how repeated rises and falls in blood pressure can harm brain blood flow and increase the risk of thinking problems in people at risk for vascular cognitive decline.
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Cuffless wireless ultrasound tattoo to monitor blood pressure
A wearable, skin-like ultrasound device will wirelessly measure and track blood pressure continuously in kids and patients, using a tiny chip and smart data signals.
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Blood pressure gene risk score used to guide treatment in adults with hypertension
A study tests whether sharing a person’s blood pressure genetic risk score helps clinicians tailor treatment and improve blood pressure control in adults with high blood pressure.
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Should we treat high blood pressure in the hospital to improve outcomes for adults during admission?
This project tests whether the way hospitals handle suddenly high blood pressure in patients admitted for any reason affects their recovery and risk of complications.
Related topics
Quick answers
How many Blood Pressure clinical trials are recruiting right now?
78, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 23 countries. The most sites are in United States (41 trials), China (8 trials), United Kingdom (4 trials), Canada (4 trials), Finland (4 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Early Phase 1: 3, Phase 4: 2, Phase 1/2: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.